(Q37510865)

20 August 2017

1 reference

title

Epoxyeicosatrienoic acids: formation, metabolism and potential role in tissue physiology and pathophysiology (English)

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20 August 2017

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Rüdiger Kaspera

1

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20 August 2017

Rheem A Totah

series ordinal

2

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20 August 2017

language of work or name

English

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publication date

1 July 2009

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Expert Opinion on Drug Metabolism & Toxicology

20 August 2017

published in

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20 August 2017

volume

5

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20 August 2017

issue

7

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20 August 2017

page(s)

757-771

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Regulated formation of eicosanoids

20 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Arachidonic acid epoxygenase. Stereochemical analysis of the endogenous epoxyeicosatrienoic acids of human kidney cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Action of epoxyeicosatrienoic acids on cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Gene structure and upstream regulatory regions of human CYP2C9 and CYP2C18

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Identification of 5,6-trans-epoxyeicosatrienoic acid in the phospholipids of red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Arachidonic acid epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Fatty acid-binding proteins inhibit hydration of epoxyeicosatrienoic acids by soluble epoxide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Prostaglandins and leukotrienes: advances in eicosanoid biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Mitochondrial P450-dependent arachidonic acid metabolism by TCDD-induced hepatic CYP1A5; conversion of EETs to DHETs by mitochondrial soluble epoxide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Novel glutathione conjugates formed from epoxyeicosatrienoic acids (EETs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Epoxygenase pathways of arachidonic acid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Epoxyeicosatrienoic acids and/or their metabolites promote hypoxic response of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Clinical relevance of the small intestine as an organ of drug elimination: drug-fruit juice interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Variability of CYP2J2 expression in human fetal tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Localization of rat cytochrome P450 in various tissues and comparison of arachidonic acid metabolism by rat P450 with that by human P450 orthologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Biosynthesis of epoxyeicosatrienoic acids varies between polymorphic CYP2C enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Cytochrome P450 2C is an EDHF synthase in coronary arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

P-450 metabolites of arachidonic acid in the control of cardiovascular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Hydrogen peroxide inhibits cytochrome p450 epoxygenases: interaction between two endothelium-derived hyperpolarizing factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

CYP2C9 allele variants in Chinese hypertension patients and healthy controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Interaction between P450 eicosanoids and nitric oxide in the control of arterial tone in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Epoxyeicosatrienoic acid prevents postischemic electrocardiogram abnormalities in an isolated heart model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Epoxyeicosatrienoic acids function as selective, endogenous antagonists of native thromboxane receptors: identification of a novel mechanism of vasodilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Erythrocyte-derived epoxyeicosatrienoic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Direct eicosanoid profiling of the hypoxic lung by comprehensive analysis via capillary liquid chromatography with dual online photodiode-array and tandem mass-spectrometric detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Role of EETs in regulation of endothelial permeability in rat lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Soluble epoxide hydrolase: regulation by estrogen and role in the inflammatory response to cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Role of endogenous CYP450 metabolites of arachidonic acid in maintaining the glomerular protein permeability barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Expression and purification of orphan cytochrome P450 4X1 and oxidation of anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Physiologic and pathophysiologic roles of lipid mediators in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Epoxyeicosatrienoic acid activates BK channels in the cortical collecting duct

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Epoxyeicosatrienoic acids affect electrolyte transport in renal tubular epithelial cells: dependence on cyclooxygenase and cell polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Measurement of eicosanoids in cancer tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Epoxyeicosatrienoic acids are part of the VEGF-activated signaling cascade leading to angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Cytochrome P450 2C9-induced angiogenesis is dependent on EphB4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Impact of genetic polymorphisms in CYP2C8 and rosiglitazone intake on the urinary excretion of dihydroxyeicosatrienoic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Distribution and expression of soluble epoxide hydrolase in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

P450 subfamily CYP2J and their role in the bioactivation of arachidonic acid in extrahepatic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425250902932923

10.1517/17425250902932923

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

1 reference