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The adenosinergic immunomodulatory drugs
scientific article published on 17 June 2009
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scholarly article
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Europe PubMed Central
PMCID
2756083
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20 August 2017
review article
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Europe PubMed Central
title
The adenosinergic immunomodulatory drugs
(English)
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Europe PubMed Central
PMCID
2756083
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20 August 2017
author name string
Akio Ohta
series ordinal
1
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Europe PubMed Central
PMCID
2756083
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20 August 2017
Michail Sitkovsky
series ordinal
2
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PMCID
2756083
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20 August 2017
publication date
17 June 2009
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Europe PubMed Central
PMCID
2756083
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20 August 2017
published in
Current Opinion in Pharmacology
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PMCID
2756083
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20 August 2017
volume
9
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Europe PubMed Central
PMCID
2756083
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20 August 2017
issue
4
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Europe PubMed Central
PMCID
2756083
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20 August 2017
page(s)
501-506
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PMCID
2756083
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20 August 2017
cites work
Immune therapy for cancer
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PubMed Central
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retrieved
23 August 2017
Hypoxia-adenosinergic immunosuppression: tumor protection by T regulatory cells and cancerous tissue hypoxia
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PubMed Central
reference URL
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retrieved
23 August 2017
A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Rapid tolerization of virus-activated tumor-specific CD8+ T cells in prostate tumors of TRAMP mice
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
A2B adenosine receptor gene deletion attenuates murine colitis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Adenosine receptors in regulation of dendritic cell differentiation and function
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PubMed Central
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23 August 2017
Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine
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PubMed Central
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23 August 2017
Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Creating immune privilege: active local suppression that benefits friends, but protects foes.
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PubMed Central
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23 August 2017
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Hypoxia in cancer: significance and impact on clinical outcome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition
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PubMed Central
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23 August 2017
Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Immune resistance orchestrated by the tumor microenvironment
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
A2A adenosine receptor protects tumors from antitumor T cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
The A2B adenosine receptor protects against inflammation and excessive vascular adhesion
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Adoptive immunotherapy for cancer: building on success
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Adenosine A2a receptors induce heterologous desensitization of chemokine receptors
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease
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PubMed Central
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23 August 2017
Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen
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PubMed Central
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23 August 2017
Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors.
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PubMed Central
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23 August 2017
Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: inhibition of chemokine induction
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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23 August 2017
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
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PubMed Central
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23 August 2017
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
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23 August 2017
Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6
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PubMed Central
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Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor
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PubMed Central
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23 August 2017
A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756083
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Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies
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PubMed Central
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Wound healing is accelerated by agonists of adenosine A2 (G alpha s-linked) receptors
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PubMed Central
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Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion
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PubMed Central
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23 August 2017
Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor
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PubMed Central
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Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism
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HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak
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PubMed Central
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The antiinflammatory effects of methotrexate are mediated by adenosine
1 reference
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reference URL
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retrieved
12 December 2020
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Identifiers
DOI
10.1016/J.COPH.2009.05.005
1 reference
stated in
Europe PubMed Central
PMCID
2756083
retrieved
20 August 2017
PMCID
2756083
1 reference
stated in
Europe PubMed Central
PMCID
2756083
retrieved
20 August 2017
PubMed ID
19539527
1 reference
stated in
Europe PubMed Central
PMCID
2756083
retrieved
20 August 2017
ResearchGate publication ID
26304334
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