(Q37535101)

English

Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity

scientific article published on 23 May 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Design, synthesis and biological assessment of novel N-substituted 3-(phthalimidin-2-yl)-2,6-dioxopiperidines and 3-substituted 2,6-dioxopiperidines for TNF-α inhibitory activity (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

0 references

author name string

Weiming Luo

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Qian-sheng Yu

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Isidro Salcedo

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Harold W Holloway

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Debomoy K Lahiri

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Arnold Brossi

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

David Tweedie

7

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Nigel H Greig

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

language of work or name

0 references

publication date

23 May 2011

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Bioorganic & Medicinal Chemistry

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

19

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

3965-3972

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

1 reference

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Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases

1 reference

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Thalidomide and analogues: potential for immunomodulation of inflammatory and neoplastic dermatologic disorders

1 reference

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Effect of thalidomide on nitric oxide production in lipopolysaccharide-activated RAW 264.7 cells.

1 reference

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A review of methods to monitor the modulation of mRNA stability: a novel approach to drug discovery and therapeutic intervention

1 reference

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Posttranscriptional regulation of TNF mRNA: a paradigm of signal-dependent mRNA utilization and its relevance to pathology

1 reference

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Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-alpha mRNA.

1 reference

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Peripheral chemo-cytokine profiles in Alzheimer's and Parkinson's diseases

1 reference

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Current status of thalidomide and CC-5013 in the treatment of metastatic prostate cancer.

1 reference

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Interventions for erythema nodosum leprosum

1 reference

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23 August 2017

A cellular model of inflammation for identifying TNF-alpha synthesis inhibitors

1 reference

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Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's disease

1 reference

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23 August 2017

Targeting mRNA stability arrests inflammatory bone loss

1 reference

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23 August 2017

Lenalidomide in the treatment of multiple myeloma: a review

1 reference

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23 August 2017

Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

23 August 2017

The role of thalidomide in the management of erythema nodosum leprosum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

23 August 2017

The role of cytokine mRNA stability in the pathogenesis of autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

23 August 2017

Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

23 August 2017

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

23 August 2017

Mechanisms of TNFα regulation in uveitis: focus on RNA-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

6 September 2017

Design, synthesis and antitumor evaluation of novel thalidomide dithiocarbamate and dithioate analogs against Ehrlich ascites carcinoma-induced solid tumor in Swiss albino mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

14 September 2017

Use of a murine cell line for identification of human nitric oxide synthase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

14 September 2017

Thiothalidomides: Novel Isosteric Analogues of Thalidomide with Enhanced TNF-α Inhibitory Activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

14 September 2017

CC-10004 but not thalidomide or lenalidomide inhibits lamina propria mononuclear cell TNF-α and MMP-3 production in patients with inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

25 June 2018

Minimal penetration of lipopolysaccharide across the murine blood-brain barrier

1 reference

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25 June 2018

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

25 June 2018

Complex regulation of tumor necrosis factor mRNA turnover in lipopolysaccharide-activated macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5187979

25 June 2018

Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.

1 reference

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1 September 2018

Prominent adverse effects of thalidomide in primary Sjögren's syndrome

1 reference

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1 September 2018

Thalidomide metabolites and analogues. 3. Synthesis and antiangiogenic activity of the teratogenic and TNFalpha-modulatory thalidomide analogue 2-(2,6-dioxopiperidine-3-yl)phthalimidine

1 reference

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1 reference

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Determination of dithiocarbamate fungicide residues in food by a spectrophotometric method using a vertical disulfide reaction system.

1 reference

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Design, synthesis and biological evaluation of new thalidomide analogues as TNF-α and IL-6 production inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21658960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/21658960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BMC.2011.05.029

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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