(Q37562075)

English

Intrathecal AAV serotype 9-mediated delivery of shRNA against TRPV1 attenuates thermal hyperalgesia in a mouse model of peripheral nerve injury

scientific article published on 28 October 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Intrathecal AAV serotype 9-mediated delivery of shRNA against TRPV1 attenuates thermal hyperalgesia in a mouse model of peripheral nerve injury (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

author name string

Takashi Hirai

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Mitsuhiro Enomoto

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Hidetoshi Kaburagi

3

1 reference

Europe PubMed Central

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21 August 2017

Shinichi Sotome

4

1 reference

Europe PubMed Central

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21 August 2017

Kie Yoshida-Tanaka

5

1 reference

Europe PubMed Central

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21 August 2017

Madoka Ukegawa

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Hiroya Kuwahara

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Mariko Yamamoto

8

1 reference

Europe PubMed Central

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21 August 2017

Mio Tajiri

9

1 reference

Europe PubMed Central

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21 August 2017

Haruka Miyata

10

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Yukihiko Hirai

11

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Makoto Tominaga

12

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Kenichi Shinomiya

13

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Hidehiro Mizusawa

14

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Atsushi Okawa

15

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Takanori Yokota

16

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

publication date

28 October 2013

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Europe PubMed Central

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21 August 2017

Molecular Therapy

1 reference

Europe PubMed Central

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21 August 2017

22

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

409-419

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Safe, long-term hepatic expression of anti-HCV shRNA in a nonhuman primate model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Enhancing the Clinical Potential of AAV Vectors by Capsid Engineering to Evade Pre-Existing Immunity

1 reference

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23 August 2017

TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Experimental models of peripheral neuropathic pain based on traumatic nerve injuries - an anatomical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial

1 reference

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23 August 2017

Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

TRP channels: targets for the relief of pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Contribution of natural products to the discovery of the transient receptor potential (TRP) channels family and their functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Thermosensation and pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

TRP ion channels in the nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

TRP channels as cellular sensors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Lessons from peppers and peppermint: the molecular logic of thermosensation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

ThermoTRP channels and beyond: mechanisms of temperature sensation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Clinical protocol. Gene therapy of Canavan disease: AAV-2 vector for neurosurgical delivery of aspartoacylase gene (ASPA) to the human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Distinct potassium channels on pain-sensing neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Spared nerve injury: an animal model of persistent peripheral neuropathic pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

Antihyperalgesic effects of infection with a preproenkephalin-encoding herpes virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

23 August 2017

TRPM3 is a nociceptor channel involved in the detection of noxious heat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

6 September 2017

Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

14 September 2017

siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

14 September 2017

Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

14 September 2017

TRPV1 in GABAergic interneurons mediates neuropathic mechanical allodynia and disinhibition of the nociceptive circuitry in the spinal cord

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

1 September 2018

Intrathecal shRNA-AAV9 inhibits target protein expression in the spinal cord and dorsal root ganglia of adult mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

1 September 2018

Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors

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1 September 2018

Silencing of mammalian genes by tetracycline-inducible shRNA expression

1 reference

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1 September 2018

Efficient regulation of viral replication by siRNA in a non-human primate surrogate model for hepatitis C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

1 September 2018

Activation of TRPA1 channel facilitates excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

1 September 2018

Vanilloid receptor-1 (TRPV1)-dependent activation of inhibitory neurotransmission in spinal substantia gelatinosa neurons of mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

1 September 2018

Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916042

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Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain

1 reference

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Peripheral inflammation induces up-regulation of TRPV2 expression in rat DRG.

1 reference

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1 September 2018

Heat hyperalgesia after incision requires TRPV1 and is distinct from pure inflammatory pain

1 reference

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Vanilloid receptor VR1-positive primary afferents are glutamatergic and contact spinal neurons that co-express neurokinin receptor NK1 and glutamate receptors

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24322332

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https://pubmed.ncbi.nlm.nih.gov/24322332

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Identifiers

10.1038/MT.2013.247

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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