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A role for Raptor phosphorylation in the mechanical activation of mTOR signaling.
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scholarly article
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Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
title
A role for Raptor phosphorylation in the mechanical activation of mTOR signaling
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
main subject
phosphorylation
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author
Brittany L Jacobs
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Craig A. Goodman
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Troy A Hornberger
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author name string
John W Frey
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
publication date
13 November 2013
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
number of pages
10
1 reference
based on heuristic
inferred from page(s)
published in
Cellular Signalling
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
volume
26
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
page(s)
313-322
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3917221/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
mTOR kinase structure, mechanism and regulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.
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PubMed Central
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23 August 2017
Mechanical stimulation induces mTOR signaling via an ERK-independent mechanism: implications for a direct activation of mTOR by phosphatidic acid
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
Osmotic stress regulates mammalian target of rapamycin (mTOR) complex 1 via c-Jun N-terminal Kinase (JNK)-mediated Raptor protein phosphorylation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
Phosphorylation of Raptor by p38beta participates in arsenite-induced mammalian target of rapamycin complex 1 (mTORC1) activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
mTOR: from growth signal integration to cancer, diabetes and ageing
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PubMed Central
reference URL
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23 August 2017
A phosphatidylinositol 3-kinase/protein kinase B-independent activation of mammalian target of rapamycin signaling is sufficient to induce skeletal muscle hypertrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
The nuts and bolts of AGC protein kinases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
AMPK phosphorylation of raptor mediates a metabolic checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
The selectivity of protein kinase inhibitors: a further update
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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23 August 2017
Mechanotransduction and the regulation of protein synthesis in skeletal muscle.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
Raptor and mTOR: Subunits of a Nutrient-Sensitive Complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
retrieved
23 August 2017
Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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6 September 2017
Strength training as a countermeasure to aging muscle and chronic disease.
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PubMed Central
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6 September 2017
Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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6 September 2017
ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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14 September 2017
Structure of the human mTOR complex I and its implications for rapamycin inhibition.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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14 September 2017
Mechanism of work-induced hypertrophy of skeletal muscle
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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14 September 2017
Relative muscle mass is inversely associated with insulin resistance and prediabetes. Findings from the third National Health and Nutrition Examination Survey.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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1 September 2018
The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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1 September 2018
Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3917221
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1 September 2018
Regulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24239769
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24239769
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24239769
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELLSIG.2013.11.009
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PMC publication ID
3917221
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed publication ID
24239769
1 reference
stated in
Europe PubMed Central
PMC publication ID
3917221
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24239769%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
ResearchGate publication ID
258635093
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