(Q37573606)

21 August 2017

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title

Cathepsin D: a protease involved in breast cancer metastasis (English)

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21 August 2017

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Rochefort H

1

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21 August 2017

Capony F

series ordinal

2

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21 August 2017

Garcia M

series ordinal

3

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21 August 2017

publication date

1 December 1990

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Cancer and Metastasis Reviews

21 August 2017

published in

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21 August 2017

volume

9

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21 August 2017

issue

4

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21 August 2017

page(s)

321-331

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Mechanism for selective secretion of a lysosomal protease by transformed mouse fibroblasts.

21 August 2017

cites work

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12 December 2020

Cathepsin D: an independent prognostic factor for metastasis of breast cancer

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12 December 2020

Tamoxifen treatment increases the concentration of 52K-cathepsin D and its precursor in breast cancer tissue

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12 December 2020

Immunoenzymatic assay of Mr 52,000 cathepsin D in 182 breast cancer cytosols: low correlation with other prognostic parameters

1 reference

12 December 2020

Cathepsin D assay in primary breast cancer and lymph nodes: Relationship with c-myc, c-erb-B-2 and int-2 oncogene amplification and node invasiveness

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12 December 2020

Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells

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12 December 2020

[Pro-cathepsin D can activate in vitro pro-cathepsin B secreted by ovarian cancers]

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12 December 2020

Cloning and sequence analysis of cDNA for human cathepsin D

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12 December 2020

Estrogens and growth factors induce the mRNA of the 52K-pro-cathepsin-D secreted by breast cancer cells

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12 December 2020

Overexpression and hormonal regulation of pro-cathepsin D in mammary and endometrial cancer.

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12 December 2020

The 52-kDa estrogen-induced protein secreted by MCF7 cells is a lysosomal acidic protease

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12 December 2020

Purification and first characterization of the secreted and cellular 52-kDa proteins regulated by estrogens in human-breast cancer cells

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12 December 2020

8th San Antonio Breast Cancer Symposium--Plenary lecture. Autocrine and paracrine growth regulation of human breast cancer

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12 December 2020

A two-site immunoenzymometric assay of 52-kDa pro-cathepsin D, and its use in human breast diseases

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12 December 2020

Distribution of the Mr 52,000 estrogen-regulated protein in benign breast diseases and other tissues by immunohistochemistry

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12 December 2020

In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells

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12 December 2020

Phosphorylation, glycosylation, and proteolytic activity of the 52-kD estrogen-induced protein secreted by MCF7 cells

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12 December 2020

Lysosomal enzymes and their receptors

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12 December 2020

The major excreted protein of transformed fibroblasts is an activable acid-protease

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12 December 2020

Release of estrogen-induced glycoprotein with a molecular weight of 52,000 by breast cancer cells in primary culture

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12 December 2020

Oestrogen regulates cathepsin D mRNA levels in oestrogen responsive human breast cancer cells

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12 December 2020

Cathepsin D. Purification of isoenzymes from human and chicken liver

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12 December 2020

Autocrine growth stimulation of the MCF 7 breast cancer cells by the estrogen-regulated 52 K protein.

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12 December 2020

Regulation of cathepsin-D and pS2 gene expression by growth factors in MCF7 human breast cancer cells

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12 December 2020

Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study

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12 December 2020

[Cathepsin D: an independent prognostic factor in cancer of the breast]

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12 December 2020

Characterization of monoclonal antibodies to the estrogen-regulated Mr 52,000 glycoprotein and their use in MCF7 cells

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12 December 2020

Association between high concentrations of Mr 52,000 cathepsin D and poor prognosis in primary human breast cancer

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12 December 2020

Identification of latent procathepsins B and L in microsomal lumen: characterization of enzymatic activation and proteolytic processing in vitro

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12 December 2020

Cancer invasion and metastases

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12 December 2020

Modulation of the transport of a lysosomal enzyme by PDGF.

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12 December 2020

Mechanism of action of high-affinity antiestrogens. An overview

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12 December 2020

Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency.

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12 December 2020

Estrogen-induced lysosomal proteases secreted by breast cancer cells: a role in carcinogenesis?

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12 December 2020

Insulin-like growth factor II receptor as a multifunctional binding protein

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12 December 2020

Estradiol increases the secretion by MCF7 cells of several lysosomal pro-enzymes

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12 December 2020

A secreted glycoprotein induced by estrogen in human breast cancer cell lines

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12 December 2020

Cathepsin D in breast cancer cells can digest extracellular matrix in large acidic vesicles

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12 December 2020

Biosynthesis of lysosomal endopeptidases

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12 December 2020

Estradiol Down-Regulates the Mannose-6-Phosphate/Insulin-Like Growth Factor-II Receptor Gene and Induces Cathepsin-D in Breast Cancer Cells: A Receptor Saturation Mechanism to Increase the Secretion of Lysosomal Proenzymes

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12 December 2020

Effects of antiestrogens on the estrogen-regulated pS2 RNA and the 52- and 160-kilodalton proteins in MCF7 cells and two tamoxifen-resistant sublines

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12 December 2020

Lysosomal cathepsin B: correlation with metastatic potential

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12 December 2020

Cloning and Sequencing of the 52K Cathepsin D Complementary Deoxyribonucleic Acid of MCF7 Breast Cancer Cells and Mapping on Chromosome 11

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12 December 2020

Cathepsin D and prognosis in breast cancer

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12 December 2020

Identifiers

DOI

10.1007/BF00049522

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21 August 2017

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