(Q37578493)

21 August 2017

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title

Prucalopride: a new drug for the treatment of chronic constipation (English)

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21 August 2017

Jan Tack

1

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21 August 2017

1 August 2009

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Expert Review of Gastroenterology & Hepatology

21 August 2017

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21 August 2017

3

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21 August 2017

4

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21 August 2017

337-343

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An epidemiological survey of constipation in canada: definitions, rates, demographics, and predictors of health care seeking

21 August 2017

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Functional bowel disorders

21 January 2018

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21 January 2018

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Treatment of chronic constipation: current pharmacologic approaches and future directions

21 January 2018

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Functional gastrointestinal disorders as a public health problem

21 January 2018

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A randomised controlled trial assessing the efficacy and safety of repeated tegaserod therapy in women with irritable bowel syndrome with constipation

21 January 2018

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Tegaserod for the treatment of chronic constipation: a randomized, double-blind, placebo-controlled multinational study

21 January 2018

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Mosapride citrate, a novel 5-HT4 agonist and partial 5-HT3 antagonist, ameliorates constipation in parkinsonian patients.

21 January 2018

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5-HT4 receptor agonists: similar but not the same

21 January 2018

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The gastrointestinal prokinetic benzamide derivatives are agonists at the non-classical 5-HT receptor (5-HT4) positively coupled to adenylate cyclase in neurons

21 January 2018

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Peristalsis evoked by 5-HT and renzapride: evidence for putative 5-HT4 receptor activation

21 January 2018

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The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound

21 January 2018

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Presynaptic modulation of cholinergic and non-cholinergic fast synaptic transmission in the myenteric plexus of guinea pig ileum

21 January 2018

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Pharmacological characterization of 5-HT4 receptors mediating relaxation of canine isolated rectum circular smooth muscle

21 January 2018

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An improved in vitro bioassay for the study of 5-HT(4) receptors in the human isolated large intestinal circular muscle

21 January 2018

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5-HT4 receptors located on cholinergic nerves in human colon circular muscle

21 January 2018

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5-HT(4) receptors on cholinergic nerves involved in contractility of canine and human large intestine longitudinal muscle

21 January 2018

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5-HT(4) receptors mediating enhancement of contractility in canine stomach; an in vitro and in vivo study

21 January 2018

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Differential effects of 5-hydroxytryptamine4 receptor agonists at gastric versus cardiac receptors: an operational framework to explain and quantify organ-specific behavior

21 January 2018

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Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach

21 January 2018

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Effect of different prokinetic agents and a novel enterokinetic agent on postoperative ileus in rats

21 January 2018

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Effects of the enterokinetic prucalopride (R093877) on colonic motility in fasted dogs

21 January 2018

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Effect of a novel prokinetic drug, R093877, on gastrointestinal transit in healthy volunteers

21 January 2018

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Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans

21 January 2018

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Effect of prucalopride, a new enterokinetic agent, on gastrointestinal transit and anorectal function in healthy volunteers

21 January 2018

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The effects of the specific 5HT(4) receptor agonist, prucalopride, on colonic motility in healthy volunteers

21 January 2018

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Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder

21 January 2018

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Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation

21 January 2018

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The action of the novel gastrointestinal prokinetic prucalopride on the HERG K+ channel and the common T897 polymorph

21 January 2018

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A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.

21 January 2018

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Electrophysiological effects of prucalopride, a novel enterokinetic agent, on isolated atrial myocytes from patients treated with beta-adrenoceptor antagonists

21 January 2018

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Selective desensitization of the 5-HT4 receptor-mediated response in pig atrium but not in stomach

21 January 2018

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Treatment of GI dysmotility in scleroderma with the new enterokinetic agent prucalopride

21 January 2018

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Prucalopride is effective in patients with severe chronic constipation in whom laxatives fail to provide adequate relief. Results of a double-blind, placebo-controlled clinical trial

21 January 2018

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Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives

21 January 2018

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A placebo-controlled trial of prucalopride for severe chronic constipation

21 January 2018

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Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation--a 12-week, randomized, double-blind, placebo-controlled study

21 January 2018

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Psychometric validation of a constipation symptom assessment questionnaire

21 January 2018

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Development and validation of the Patient Assessment of Constipation Quality of Life questionnaire

21 January 2018

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Efficacy and tolerability of prucalopride in patients with constipation due to spinal cord injury

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/EGH.09.38

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21 August 2017

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PubMed ID

19673621