(Q37585335)

English

Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis.

scholarly article

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15477603%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15477603%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

crystal structure

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

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4 January 2020

5

1 reference

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4 January 2020

author name string

Hiroshi Nii

2

1 reference

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4 January 2020

Toru Nakatsu

3

1 reference

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4 January 2020

Akira Kimura

4

1 reference

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4 January 2020

Jun Hiratake

6

1 reference

Europe PubMed Central

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4 January 2020

Jun'ichi Oda

7

1 reference

Europe PubMed Central

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4 January 2020

language of work or name

0 references

publication date

11 October 2004

1 reference

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4 January 2020

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

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4 January 2020

101

1 reference

Europe PubMed Central

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4 January 2020

15052-15057

1 reference

Europe PubMed Central

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4 January 2020

42

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15477603%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

MAD phasing: treatment of dispersive differences as isomorphous replacement information

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Strategies for reversing drug resistance

1 reference

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23 August 2017

Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Maximum-likelihood density modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Regulation of glutathione synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Enzymes of vancomycin resistance: the structure of D-alanine-D-lactate ligase of naturally resistant Leuconostoc mesenteroides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Multi-faceted regulation of gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Biologic and pharmacologic regulation of mammalian glutathione synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

The molecular basis of a case of gamma-glutamylcysteine synthetase deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

How do kinases transfer phosphoryl groups?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

A pseudo-michaelis quaternary complex in the reverse reaction of a ligase: structure of Escherichia coli B glutathione synthetase complexed with ADP, glutathione, and sulfate at 2.0 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Vancomycin resistance: structure of D-alanine:D-alanine ligase at 2.3 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

WHAT IF: a molecular modeling and drug design program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

23 August 2017

Substrate binding determinants of Trypanosoma brucei gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

6 September 2017

Plasmodium falciparum-infected red blood cells depend on a functional glutathione de novo synthesis attributable to an enhanced loss of glutathione

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

6 September 2017

Retroviral transfer of MRP1 and gamma-glutamyl cysteine synthetase modulates cell sensitivity to L-buthionine-S,R-sulphoximine (BSO): new rationale for the use of BSO in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

25 June 2018

Recognition of a cysteine substrate by E. coli gamma-glutamylcysteine synthetase probed by sulfoximine-based transition-state analogue inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

1 September 2018

Escherichia coli B gamma-glutamylcysteine synthetase: modification, purification, crystallization and preliminary crystallographic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

1 September 2018

Escherichia coli gamma-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

1 September 2018

Structure prediction and active site analysis of the metal binding determinants in gamma -glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523444

1 September 2018

MOLREP: an Automated Program for Molecular Replacement

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403277101

21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403277101

21 January 2018

Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15477603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic evidence for a dual cation role for muscle pyruvate kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15477603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione

1 reference

https://pubmed.ncbi.nlm.nih.gov/15477603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione: an overview of biosynthesis and modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15477603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CORRELATION OF STRUCTURE AND FUNCTION IN ENZYME ACTION

1 reference

https://pubmed.ncbi.nlm.nih.gov/15477603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-S,R-buthionine sulfoximine: historical development and clinical issues

1 reference

https://pubmed.ncbi.nlm.nih.gov/15477603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design, synthesis and evaluation of transition-state analogue inhibitors of Escherichia coli gamma-glutamylcysteine synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15477603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0403277101

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15477603%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

2004PNAS..10115052H

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15477603%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15477603%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

ResearchGate publication ID

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