(Q37585413)

English

ADX71441, a novel, potent and selective positive allosteric modulator of the GABA(B) receptor, shows efficacy in rodent models of overactive bladder

scientific article published on February 2014

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

ADX71441, a novel, potent and selective positive allosteric modulator of the GABA(B) receptor, shows efficacy in rodent models of overactive bladder (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

author name string

M Kalinichev

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

S Palea

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

H Haddouk

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

I Royer-Urios

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

V Guilloteau

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

P Lluel

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

M Schneider

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

M Saporito

8

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

S Poli

9

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

language of work or name

0 references

publication date

1 February 2014

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

171

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

995-1006

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

The Concise Guide to PHARMACOLOGY 2013/14: overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Animal research: reporting in vivo experiments: the ARRIVE guidelines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

The forefront for novel therapeutic agents based on the pathophysiology of lower urinary tract dysfunction: bladder selectivity based on in vivo drug-receptor binding characteristics of antimuscarinic agents for treatment of overactive bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Allosteric modulators of GABA(B) receptors: mechanism of action and therapeutic perspective.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

GABA receptor activation in the lumbosacral spinal cord decreases detrusor overactivity in spinal cord injured rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Pharmacologic management of overactive bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Management of overactive bladder and urge urinary incontinence in the elderly patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Pathophysiology of overactive bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Animal models in urological disease and sexual dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Management of overactive bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

23 August 2017

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

6 September 2017

A Double-blind Crossover Trial of Baclofen-a New Treatment for the Unstable Bladder Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

28 September 2017

A Double-Blind Trial with the Antispasticity Drug Lioresal® in 15 Paraplegics with Upper Neuron Lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

28 September 2017

GABA and its receptors in the spinal cord

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

28 September 2017

Reduction of excessive alcohol drinking by a novel GABAB receptor positive allosteric modulator ADX71441 in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

25 June 2018

Modulation of detrusor contraction strength and micturition characteristics by intrathecal baclofen in anesthetized rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

25 June 2018

GABAB receptor mediated inhibition of field stimulation-induced contractions of rabbit bladder muscle in-vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

25 June 2018

Rapid evaluation of the efficacy of pharmacologic agents and their analogs in enhancing bladder capacity and reducing the voiding frequency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

25 June 2018

A method for producing overactive bladder in the rat and investigation of the effects of GABAergic receptor agonists and glutamatergic receptor antagonists on the cystometrogram

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

1 September 2018

Effects of gamma-aminobutyrate B receptor modulation on normal micturition and oxyhemoglobin induced detrusor overactivity in female rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

1 September 2018

The effect of alpha 2 agonists and antagonists on the lower urinary tract of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

1 September 2018

GABAA and GABAB receptors in detrusor strips from guinea-pig bladder dome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

1 September 2018

Regional differences in the motor response to capsaicin in the guinea-pig urinary bladder: relative role of pre- and postjunctional factors related to neuropeptide-containing sensory nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3925038

1 September 2018

Effects of GABA-receptor stimulation and blockade on micturition in normal rats and rats with bladder outflow obstruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/24224799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor localization in the mammalian dorsal horn and primary afferent neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24224799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunctional voiding confirmed by transdermal perineal electromyography, and its effective treatment with baclofen in women with lower urinary tract symptoms: a randomized double-blind placebo-controlled crossover trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/24224799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory Role of Gamma‐amino‐butyric Acid in the Rabbit Urinary Bladder

1 reference

https://pubmed.ncbi.nlm.nih.gov/24224799

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/BPH.12517

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37585413&oldid=2112087249"