(Q37590348)

21 August 2017

1 reference

title

DNA vaccine manufacture: scale and quality (English)

1 reference

21 August 2017

1 reference

Ying Cai

1

1 reference

21 August 2017

Stephen Rodriguez

series ordinal

2

1 reference

21 August 2017

Henry Hebel

series ordinal

3

1 reference

21 August 2017

publication date

1 September 2009

1 reference

Expert Review of Vaccines

21 August 2017

published in

1 reference

21 August 2017

volume

8

1 reference

21 August 2017

issue

9

1 reference

21 August 2017

page(s)

1277-1291

1 reference

Direct gene transfer into mouse muscle in vivo

21 August 2017

cites work

1 reference

A West Nile Virus DNA Vaccine Induces Neutralizing Antibody in Healthy Adults during a Phase 1 Clinical Trial

21 January 2018

1 reference

Development of a xenogeneic DNA vaccine program for canine malignant melanoma at the Animal Medical Center.

21 January 2018

1 reference

Growth hormone-releasing hormone plasmid treatment by electroporation decreases offspring mortality over three pregnancies

21 January 2018

1 reference

Plasmid DNA manufacturing technology

21 January 2018

1 reference

Development of process flow sheets for the purification of supercoiled plasmids for gene therapy applications

21 January 2018

1 reference

Vaccination with polymerase chain reaction-generated linear expression cassettes protects mice against lethal influenza A challenge

21 January 2018

1 reference

Evaluation of tumor-specific promoter activities in melanoma.

21 January 2018

1 reference

DNA vaccines: developing new strategies to enhance immune responses

21 January 2018

1 reference

Optimization of a DNA vaccine against SARS.

21 January 2018

1 reference

Effect of plasmid backbone modification by different human CpG motifs on the immunogenicity of DNA vaccine vectors

21 January 2018

1 reference

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.

21 January 2018

1 reference

pCOR: a new design of plasmid vectors for nonviral gene therapy

21 January 2018

1 reference

Plasmid DNA vaccine vector design: impact on efficacy, safety and upstream production

21 January 2018

1 reference

Engineering of bacterial strains and vectors for the production of plasmid DNA.

21 January 2018

1 reference

Host strain influences on supercoiled plasmid DNA production in Escherichia coli: Implications for efficient design of large-scale processes

21 January 2018

1 reference

Modified Escherichia coli B (BL21), a superior producer of plasmid DNA compared with Escherichia coli K (DH5alpha).

21 January 2018

1 reference

Escherichia coli strains that allow antibiotic-free plasmid selection and maintenance by repressor titration

21 January 2018

1 reference

Separate-component-stabilization system for protein and DNA production without the use of antibiotics

21 January 2018

1 reference

Inducible Escherichia coli fermentation for increased plasmid DNA production.

21 January 2018

1 reference

Growth medium selection and its economic impact on plasmid DNA production

21 January 2018

1 reference

Effects of growth medium selection on plasmid DNA production and initial processing steps

21 January 2018

1 reference

Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes.

21 January 2018

1 reference

Impact of engineering flow conditions on plasmid DNA yield and purity in chemical cell lysis operations.

21 January 2018

1 reference

Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device.

21 January 2018

1 reference

Design of expanded bed supports for the recovery of plasmid DNA by anion exchange adsorption

21 January 2018

1 reference

Precipitation of RNA impurities with high salt in a plasmid DNA purification process: use of experimental design to determine reaction conditions.

21 January 2018

1 reference

Removal of RNA impurities by tangential flow filtration in an RNase-free plasmid DNA purification process

21 January 2018

1 reference

Cancer Gene Therapy Using Plasmid DNA: Purification of DNA for Human Clinical Trials

21 January 2018

1 reference

Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies

21 January 2018

1 reference

Supercoiled plasmid DNA: selective purification by thiophilic/aromatic adsorption

21 January 2018

1 reference

Production of plasmid DNA for human gene therapy using modified alkaline cell lysis and expanded bed anion exchange chromatography

21 January 2018

1 reference

Separation of genomic DNA from plasmid DNA by selective renaturation with immobilized metal affinity capture

21 January 2018

1 reference

DNA purification by triple-helix affinity precipitation

21 January 2018

1 reference

Selective purification of supercoiled plasmid DNA from clarified cell lysates with a single histidine-agarose chromatography step.

21 January 2018

1 reference

Affinity purification of plasmid DNA directly from crude bacterial cell lysates.

21 January 2018

1 reference

Scalable recovery of plasmid DNA based on aqueous two-phase separation.

21 January 2018

1 reference

Electroporation of synthetic DNA antigens offers protection in nonhuman primates challenged with highly pathogenic avian influenza virus

21 January 2018

1 reference

Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens

21 January 2018

1 reference

Cellular immunity induced by a novel HPV18 DNA vaccine encoding an E6/E7 fusion consensus protein in mice and rhesus macaques

21 January 2018

1 reference

GMP production of pDERMATT for vaccination against melanoma in a phase I clinical trial

21 January 2018

1 reference

Large-scale plasmid DNA processing: evidence that cell harvesting and storage methods affect yield of supercoiled plasmid DNA.

21 January 2018

1 reference

Large-scale capture and partial purification of plasmid DNA using anion-exchange membrane capsules

21 January 2018

1 reference

Purification of plasmid DNA using tangential flow filtration and tandem anion-exchange membrane chromatography.

21 January 2018

1 reference

Compaction agent protection of nucleic acids during mechanical lysis.

21 January 2018

1 reference

Ultra scale-down to define and improve the relationship between flocculation and disc-stack centrifugation

21 January 2018

1 reference

Purification of plasmid DNA by an integrated operation comprising tangential flow filtration and nitrocellulose adsorption

21 January 2018

1 reference

Chromatography-free recovery of biopharmaceuticals through aqueous two-phase processing.

21 January 2018

1 reference

Purification of plasmid DNA vectors by aqueous two-phase extraction and hydrophobic interaction chromatography

21 January 2018

1 reference

Alternatives for the intermediate recovery of plasmid DNA: performance, economic viability and environmental impact.

21 January 2018

1 reference

Thiophilic interaction chromatography for supercoiled plasmid DNA purification

21 January 2018

1 reference

Application of monoliths for plasmid DNA purification development and transfer to production

21 January 2018

1 reference

Large-volume methacrylate monolith for plasmid purification. Process engineering approach to synthesis and application

21 January 2018

1 reference

Enhancing methacrylate-monolith-based downstream processes to champion plasmid DNA production.

21 January 2018

1 reference

Fractional precipitation of plasmid DNA from lysate by CTAB.

21 January 2018

1 reference

Sequential CaCl2, polyethylene glycol precipitation for RNase-free plasmid DNA isolation.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERV.09.84

1 reference

21 August 2017

1 reference