(Q37596042)

English

Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats

scientific article published on 30 March 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Age-Related Decline in Brain and Hepatic Clearance of Amyloid-Beta is Rectified by the Cholinesterase Inhibitors Donepezil and Rivastigmine in Rats (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

author name string

Loqman A Mohamed

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Hisham Qosa

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Amal Kaddoumi

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

publication date

30 March 2015

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

ACS Chemical Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

725-736

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.

1 reference

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Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies

1 reference

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Neurovascular dysfunction and faulty amyloid β-peptide clearance in Alzheimer disease

1 reference

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Neurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's disease

1 reference

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Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease

1 reference

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23 August 2017

Withania somnifera reverses Alzheimer's disease pathology by enhancing low-density lipoprotein receptor-related protein in liver

1 reference

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Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products

1 reference

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Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons

1 reference

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Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-β is an early biomarker for mild cognitive impairment preceding Alzheimer's disease

1 reference

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Decreased clearance of CNS beta-amyloid in Alzheimer's disease

1 reference

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Galantamine-induced amyloid-{beta} clearance mediated via stimulation of microglial nicotinic acetylcholine receptors

1 reference

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Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of alpha7 nicotinic receptors and internalization of NMDA receptors

1 reference

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Alzheimer's disease: strategies for disease modification

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A hundred years of Alzheimer's disease research

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23 August 2017

Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family

1 reference

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23 August 2017

The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease.

1 reference

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23 August 2017

Neurovascular mechanisms of Alzheimer's neurodegeneration

1 reference

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23 August 2017

Alzheimer's disease and the amyloid cascade hypothesis: ten years on.

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23 August 2017

Alzheimer's disease: genes, proteins, and therapy

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23 August 2017

Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein.

1 reference

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23 August 2017

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

1 reference

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Acetylcholine in mind: a neurotransmitter correlate of consciousness?

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23 August 2017

The glutamatergic system and neurodegeneration in dementia: preventive strategies in Alzheimer's disease

1 reference

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23 August 2017

A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group

1 reference

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23 August 2017

The Alzheimer family of diseases: many etiologies, one pathogenesis?

1 reference

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The molecular pathology of Alzheimer's disease

1 reference

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Chapter 4 Preparation of Isolated Rat Liver Cells

1 reference

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Donepezil inhibits the amyloid-beta oligomer-induced microglial activation in vitro and in vivo

1 reference

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Neurotoxicity of amyloid β-protein: synaptic and network dysfunction

1 reference

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LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

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14 September 2017

Predictors of long-term treatment effect of rivastigmine in Alzheimer's disease: a role for beta-amyloid plasma levels?

1 reference

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P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

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Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease

1 reference

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Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.

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Amyloid efflux transporter expression at the blood-brain barrier declines in normal aging.

1 reference

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Plasma Abeta levels as predictors of response to rivastigmine treatment in Alzheimer's disease.

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MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier

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Cholinesterase inhibitors reduce cortical Abeta in dementia with Lewy bodies.

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Donepezil induces a cholinergic sprouting in basocortical degeneration.

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Functional characterization of the brain-to-blood efflux clearance of human amyloid-beta peptide (1-40) across the rat blood-brain barrier.

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Memantine prevents quinolinic acid-induced hippocampal damage

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Major involvement of low-density lipoprotein receptor-related protein 1 in the clearance of plasma free amyloid beta-peptide by the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/25782004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain efflux index as a novel method of analyzing efflux transport at the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/25782004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/ACSCHEMNEURO.5B00040

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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