(Q37609369)

English

A monoclonal antibody against alphaVbeta3 integrin inhibits development of atherosclerotic lesions in diabetic pigs

scientific article published on February 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

A monoclonal antibody against alphaVbeta3 integrin inhibits development of atherosclerotic lesions in diabetic pigs (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

atherosclerosis

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

monoclonal antibody

1 reference

based on heuristic

inferred from title

author name string

Laura A Maile

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Walker H Busby

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Timothy C Nichols

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Dwight A Bellinger

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Elizabeth P Merricks

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Michael Rowland

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Umadevi Veluvolu

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

David R Clemmons

8

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

language of work or name

0 references

publication date

1 February 2010

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Science Translational Medicine

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

18

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

18ra11

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Expression of integrins in human proliferative diabetic retinopathy membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

High glucose promotes retinal endothelial cell migration through activation of Src, PI3K/Akt1/eNOS, and ERKs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Cell type-specific post-transcriptional regulation of production of the potent antiangiogenic and proatherogenic protein thrombospondin-1 by high glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

The importance of treating multiple cardiometabolic risk factors in patients with Type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Screening for coronary artery disease in patients with diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Cross-talk between IGF-I and estradiol in the brain: focus on neuroprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Conformation and concerted dynamics of the integrin-binding site and the C-terminal region of echistatin revealed by homonuclear NMR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

The ?5?1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Hypoxia and high glucose cause exaggerated mesangial cell growth and collagen synthesis: role of osteopontin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Blocking ligand occupancy of the alphaVbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

23 August 2017

Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

14 September 2017

Insulin-like growth factor-1 receptor activation inhibits oxidized LDL-induced cytochrome C release and apoptosis via the phosphatidylinositol 3 kinase/Akt signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

14 September 2017

An allosteric Ca2+ binding site on the beta3-integrins that regulates the dissociation rate for RGD ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

28 September 2017

Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for embrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth factor I receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

25 June 2018

Stabile D-peptide analog of insulin-like growth factor-1 inhibits smooth muscle cell proliferation after carotid ballooning injury in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

25 June 2018

Development of coronary atherosclerosis in swine with severe hypercholesterolemia. Lack of influence of von Willebrand factor or acute intimal injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

25 June 2018

Effects of hypophysectomy on vascular insulin-like growth factor-I gene expression after balloon denudation in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

25 June 2018

Regulation of vascular smooth muscle cell integrin expression by transforming growth factor β1 and by platelet‐derived growth factor‐BB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

25 June 2018

Protease-resistant insulin-like growth factor (IGF)-binding protein-4 inhibits IGF-I actions and neointimal expansion in a porcine model of neointimal hyperplasia.

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Insulin-like growth factor-I protects granule neurons from apoptosis and improves ataxia in weaver mice

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Hyperglycemia-induced alteration of vascular smooth muscle phenotype

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I.

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Reduction in atherosclerotic lesion size in pigs by alphaVbeta3 inhibitors is associated with inhibition of insulin-like growth factor-I-mediated signaling

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Insulin-like growth factor-I signaling in smooth muscle cells is regulated by ligand binding to the 177CYDMKTTC184 sequence of the beta3-subunit of alphaVbeta3.

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

The heparin binding domain of vitronectin is the region that is required to enhance insulin-like growth factor-I signaling

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Beta3-integrin mediates smooth muscle cell accumulation in neointima after carotid ligation in mice

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Multi-year follow-up of abciximab therapy in three randomized, placebo-controlled trials of percutaneous coronary revascularization

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Kidney involvement in a nongenetic rat model of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Hypoxia stimulates osteopontin expression and proliferation of cultured vascular smooth muscle cells: potentiation by high glucose

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Glucose-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase-dependent upregulation of the platelet-derived growth factor-beta receptor potentiates vascular smooth muscle cell chemotaxis.

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Comparison of random and oriented immobilisation of antibody fragments on mixed self-assembled monolayers.

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Diabetes-induced accelerated atherosclerosis in swine

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000476

21 January 2018

Targeted overexpression of IGF-I in smooth muscle cells of transgenic mice enhances neointimal formation through increased proliferation and cell migration after intraarterial injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3938114

1 September 2018

Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of insulin-like growth factor I and inhibition of coronary smooth muscle cell growth by somatostatin analogues in human coronary smooth muscle cells. A potential treatment for restenosis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor (IGF)-binding proteins inhibit the smooth muscle cell migration responses to IGF-I and IGF-II

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

α v β 3 Integrin Expression in Normal and Atherosclerotic Artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta3 integrins are upregulated after vascular injury and modulate thrombospondin- and thrombin-induced proliferation of cultured smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective alpha v beta 3 integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: evidence for the functional importance of integrin alpha v beta 3 and osteopontin expression during n

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II activation of insulin-like growth factor 1 receptor transcription is mediated by a tyrosine kinase-dependent redox-sensitive mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombospondin and osteopontin bind to insulin-like growth factor (IGF)-binding protein-5 leading to an alteration in IGF-I-stimulated cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abciximab Inhibits the Migration and Invasion Potential of Human Coronary Artery Smooth Muscle Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1126/SCITRANSLMED.3000476

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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