(Q37612636)

21 August 2017

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title

IL-5- and eosinophil-mediated inflammation: from discovery to therapy (English)

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21 August 2017

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Taku Kouro

1

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21 August 2017

Kiyoshi Takatsu

series ordinal

2

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21 August 2017

publication date

9 October 2009

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21 August 2017

published in

International Immunology

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21 August 2017

volume

21

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21 August 2017

issue

12

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21 August 2017

page(s)

1303-1309

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Interleukin 5 messenger RNA expression by eosinophils in the intestinal mucosa of patients with coeliac disease

21 August 2017

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21 January 2018

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Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation.

21 January 2018

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CD4(-)c-kit(-)CD3epsilon(-)IL-2Ralpha(+) Peyer's patch cells are a novel cell subset which secrete IL-5 in response to IL-2: implications for their role in IgA production

21 January 2018

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Molecular cloning and expression of the human interleukin 5 receptor

21 January 2018

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A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor alpha chain and its function in IL-5-mediated growth signal transduction

21 January 2018

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Critical proline residues of the cytoplasmic domain of the IL-5 receptor alpha chain and its function in IL-5-mediated activation of JAK kinase and STAT5.

21 January 2018

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Functional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cells

21 January 2018

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Interleukin 5 in the link between the innate and acquired immune response

21 January 2018

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21 January 2018

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The lineage decisions of helper T cells

21 January 2018

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Immunologic basis of antigen-induced airway hyperresponsiveness

21 January 2018

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21 January 2018

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A role for eosinophils in airway remodelling in asthma

21 January 2018

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Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin

21 January 2018

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Thymic stromal lymphopoietin: master switch for allergic inflammation

21 January 2018

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Role of cytokines in allergic airway inflammation

21 January 2018

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Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors

21 January 2018

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21 January 2018

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Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production

21 January 2018

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Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains

21 January 2018

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21 January 2018

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21 January 2018

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Lyn, Jak2, and Raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only Raf-1 kinase is essential for eosinophil activation and degranulation

21 January 2018

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IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases

21 January 2018

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Src homology 2 protein tyrosine phosphatase (SHPTP2)/Src homology 2 phosphatase 2 (SHP2) tyrosine phosphatase is a positive regulator of the interleukin 5 receptor signal transduction pathways leading to the prolongation of eosinophil survival

21 January 2018

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Essential role of Stat5 for IL-5-dependent IgH switch recombination in mouse B cells

21 January 2018

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Transduction of a dominant-negative H-Ras into human eosinophils attenuates extracellular signal-regulated kinase activation and interleukin-5-mediated cell viability

21 January 2018

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JAK kinases control IL-5 receptor ubiquitination, degradation, and internalization.

21 January 2018

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Spred-1 negatively regulates allergen-induced airway eosinophilia and hyperresponsiveness

21 January 2018

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IL-5 and granulocyte-macrophage colony-stimulating factor activate STAT3 and STAT5 and promote Pim-1 and cyclin D3 protein expression in human eosinophils

21 January 2018

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Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo

21 January 2018

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Identification of eosinophil lineage-committed progenitors in the murine bone marrow

21 January 2018

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Multi-colony stimulating activity of interleukin 5 (IL-5) on hematopoietic progenitors from transgenic mice that express IL-5 receptor alpha subunit constitutively

21 January 2018

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Expression of IL-5Ralpha on B-1 cell progenitors in mouse fetal liver and involvement of Bruton's tyrosine kinase in their development

21 January 2018

1 reference

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Regulation of interleukin-5-induced beta2-integrin adhesion of human eosinophils by phosphoinositide 3-kinase

21 January 2018

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A role for Bid in eosinophil apoptosis and in allergic airway reaction.

21 January 2018

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Asthma: mechanisms of disease persistence and progression

21 January 2018

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Allergen-induced airway hyperresponsiveness

21 January 2018

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Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma

21 January 2018

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Effect of anti-IL-5 and IL-5 on airway hyperreactivity and eosinophils in guinea pigs

21 January 2018

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Antibody against interleukin-5 prevents antigen-induced eosinophil infiltration and bronchial hyperreactivity in the guinea pig airways

21 January 2018

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Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

21 January 2018

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Allergen-induced airway inflammation and bronchial responsiveness in interleukin-5 receptor alpha chain-deficient mice

21 January 2018

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Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

21 January 2018

1 reference

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Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study.

21 January 2018

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Mepolizumab and exacerbations of refractory eosinophilic asthma

21 January 2018

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Mepolizumab for prednisone-dependent asthma with sputum eosinophilia

21 January 2018

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A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma.

21 January 2018

1 reference

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Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice

21 January 2018

1 reference

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Treatment of patients with the hypereosinophilic syndrome with mepolizumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXP102

Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXP102

21 January 2018

Identifiers

DOI

10.1093/INTIMM/DXP102

1 reference

21 August 2017

1 reference