(Q37617353)

21 August 2017

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title

Factors that retard remyelination in multiple sclerosis with a focus on TIP30: a novel therapeutic target (English)

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21 August 2017

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3

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21 August 2017

Jin Nakahara

1

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21 August 2017

Sadakazu Aiso

series ordinal

2

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21 August 2017

language of work or name

English

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publication date

1 December 2009

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Expert Opinion on Therapeutic Targets

21 August 2017

published in

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21 August 2017

volume

13

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21 August 2017

issue

12

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21 August 2017

page(s)

1375-1386

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What the fly's glia tell the fly's brain

21 August 2017

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21 January 2018

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White matter integrity in the vicinity of Broca's area predicts grammar learning success

21 January 2018

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Extensive piano practicing has regionally specific effects on white matter development.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease?

21 January 2018

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Recent clinical trials and future therapies

21 January 2018

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Extensive remyelination of the CNS leads to functional recovery

21 January 2018

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The oligodendrocyte precursor cell in health and disease

21 January 2018

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PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination

21 January 2018

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Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system

21 January 2018

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Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS.

21 January 2018

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Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

21 January 2018

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Remyelination in the CNS: from biology to therapy

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

Remyelination is extensive in a subset of multiple sclerosis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Remyelination capacity of the MS brain decreases with disease chronicity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

Multiple sclerosis: an immune or neurodegenerative disorder?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

Axonal protection in multiple sclerosis--a particular need during remyelination?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

Why does remyelination fail in multiple sclerosis?

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903307491

Negative regulation of central nervous system myelination by polysialylated-neural cell adhesion molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Re-expression of PSA-NCAM by demyelinated axons: an inhibitor of remyelination in multiple sclerosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

LINGO-1 negatively regulates myelination by oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Initial events of myelination involve Fyn tyrosine kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Signaling from integrins to Fyn to Rho family GTPases regulates morphologic differentiation of oligodendrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Inflammation stimulates remyelination in areas of chronic demyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Endogenous remyelination is induced by transplant rejection in a viral model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Remyelination can be extensive in multiple sclerosis despite a long disease course

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Steroids for multiple sclerosis and optic neuritis: a meta-analysis of randomized controlled clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Truncated Tau with the Fyn-binding domain and without the microtubule-binding domain hinders the myelinating capacity of an oligodendrocyte cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Tyrosine phosphorylation of p190 RhoGAP by Fyn regulates oligodendrocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Process elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Focal adhesion kinase regulates laminin-induced oligodendroglial process outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Cdk5 phosphorylation of WAVE2 regulates oligodendrocyte precursor cell migration through nonreceptor tyrosine kinase Fyn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Signaling via immunoglobulin Fc receptors induces oligodendrocyte precursor cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Inhibition of Src-like kinases reveals Akt-dependent and -independent pathways in insulin-like growth factor I-mediated oligodendrocyte progenitor survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Muscarinic acetylcholine receptors mediate oligodendrocyte progenitor survival through Src-like tyrosine kinases and PI3K/Akt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Nucleocytoplasmic transport: taking an inventory

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TIP30 mutant derived from hepatocellular carcinoma specimens promotes growth of HepG2 cells through up-regulation of N-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Deletion of Tip30 leads to rapid immortalization of murine mammary epithelial cells and ductal hyperplasia in the mammary gland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TIP30/CC3 expression in breast carcinoma: relation to metastasis, clinicopathologic parameters, and P53 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Decreased TIP30 expression promotes tumor metastasis in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TIP30 is associated with progression and metastasis of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TIP30 interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates c-myc transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Thirty-kilodalton Tat-interacting protein suppresses tumor metastasis by inhibition of osteopontin transcription in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TIP30 regulates apoptosis-related genes in its apoptotic signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Tip30-induced apoptosis requires translocation of Bax and involves mitochondrial release of cytochrome c and Smac/DIABLO in hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Metastasis suppressor CC3 inhibits angiogenic properties of tumor cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

TIP30, a cofactor for HIV-1 Tat-activated transcription, is homologous to short-chain dehydrogenases/reductases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Three-dimensional model of human TIP30, a coactivator for HIV-1 Tat-activated transcription, and CC3, a protein associated with metastasis suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Crystal structure of CC3 (TIP30): implications for its role as a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Inhibition of nuclear import by the proapoptotic protein CC3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Analysis of heat-shock related gene expression in head-and-neck cancer using cDNA arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

The transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Differentially expressed CC3/TIP30 and rab11 along in vivo and in vitro intestinal epithelial cell crypt-villus axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Activation of a prometastatic gene expression program in hypoxic neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Methylation of Tip30 promoter is associated with poor prognosis in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Nuclear pore complex proteins in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Magnetization transfer ratio evolution with demyelination and remyelination in multiple sclerosis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903307491

10.1517/14728220903307491

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference