(Q37623805)

English

Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome

scientific article published on October 16, 1995

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21 October 2019

Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome (English)

1 reference

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21 October 2019

apoptotic process

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M. Peled-Kamar

1

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27 May 2024

J. Lotem

2

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27 May 2024

E. Okon

3

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27 May 2024

L. Sachs

4

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27 May 2024

Y. Groner

5

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27 May 2024

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1 October 1995

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21 October 2019

16 October 1995

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7588627

27 May 2024

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https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1995.tb00181.x

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27 May 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7588627/?tool=EBI

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27 May 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7588627/pdf/?tool=EBI

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27 May 2024

https://europepmc.org/articles/PMC394602

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Europe PubMed Central

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27 May 2024

https://europepmc.org/articles/PMC394602?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7588627

27 May 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fj.1460-2075.1995.tb00181.x

1 reference

10.1002/J.1460-2075.1995.TB00181.X

https://api.crossref.org/works/10.1002/J.1460-2075.1995.TB00181.X

27 May 2024

http://onlinelibrary.wiley.com/wol1/doi/10.1002/j.1460-2075.1995.tb00181.x/fullpdf

1 reference

10.1002/J.1460-2075.1995.TB00181.X

https://api.crossref.org/works/10.1002/J.1460-2075.1995.TB00181.X

27 May 2024

The EMBO Journal

1 reference

Europe PubMed Central

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21 October 2019

14

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Europe PubMed Central

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21 October 2019

20

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7588627%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

4985-4993

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7588627%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Signal transduction pathways to apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Autocrine production of extracellular catalase prevents apoptosis of the human CEM T-cell line in serum-free medium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Oxidants, antioxidants, and the degenerative diseases of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

In vivo induction of apoptosis (programmed cell death) in mouse thymus by administration of lipopolysaccharide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Down syndrome phenotypes: the consequences of chromosomal imbalance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Overexpression of liver-type phosphofructokinase (PFKL) in transgenic-PFKL mice: implication for gene dosage in trisomy 21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Transgenic copper/zinc superoxide dismutase modulates susceptibility to type I diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Stem cell deficiencies and thymic abnormalities in fetal mouse trisomy 16.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Endotoxaemia: an early predictor of septicaemia in febrile patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Diminished serotonin uptake in platelets of transgenic mice with increased Cu/Zn-superoxide dismutase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Transgenic mice with expression of elevated levels of copper-zinc superoxide dismutase in the lungs are resistant to pulmonary oxygen toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Apoptosis: Mechanisms and Roles in Pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Reactive oxygen species and the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Dysregulation of gene expression in mouse trisomy 16, an animal model of Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

23 August 2017

Down's syndrome and the molecular biology of chromosome 21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

6 September 2017

The molecular control of blood cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

14 September 2017

The adventures of a biologist: prenatal diagnosis, hematopoiesis, leukemia, carcinogenesis, and tumor suppression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

14 September 2017

A radical hypothesis for neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

14 September 2017

Clinical aspects of Down's syndrome from infancy to adult life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

14 September 2017

Reduced Number of Peripheral Blood Granulocytic Progenitor Cells in Patients with Down's Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

14 September 2017

Thymic deficiency in Down's syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

14 September 2017

Human chromosome 21: genome mapping and exploration, circa 1993.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

28 September 2017

Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

28 September 2017

Control of programmed cell death in normal and leukemic cells: new implications for therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

28 September 2017

The double-edged role of nitric oxide in brain function and superoxide-mediated injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

28 September 2017

Transfection with human copper-zinc superoxide dismutase induces bidirectional alterations in other antioxidant enzymes, proteins, growth factor response, and paraquat resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

28 September 2017

The Bcl-2 oncoprotein functions as a pro-oxidant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

28 September 2017

Architecture and anatomy of the chromosomal locus in human chromosome 21 encoding the Cu/Zn superoxide dismutase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

28 September 2017

Glutathione peroxidase compensates for the hypersensitivity of Cu,Zn-superoxide dismutase overproducers to oxidant stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Sepsis-induced apoptosis of the thymocytes in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Inhibition of activation-induced death in T cell hybridomas by thiol antioxidants: oxidative stress as a mediator of apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Parinaric acid as a sensitive fluorescent probe for the determination of lipid peroxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Overproduction of human Cu/Zn-superoxide dismutase in transfected cells: extenuation of paraquat-mediated cytotoxicity and enhancement of lipid peroxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Prevention of gram-negative shock and death in surgical patients by antibody to endotoxin core glycolipid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Detection of circulating tumor necrosis factor after endotoxin administration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Down syndrome clinical symptoms are manifested in transfected cells and transgenic mice overexpressing the human Cu/Zn-superoxide dismutase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

The balance between copper-zinc superoxide dismutase and catalase affects the sensitivity of mouse epidermal cells to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Down syndrome (DS) peripheral blood contains phenotypically mature CD3+TCR alpha, beta+ cells but abnormal proportions of TCR alpha, beta+, TCR gamma, delta+, and CD4+ CD45RA+ cells: evidence for an inefficient release of mature T cells by the DS th

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

25 June 2018

Hematopoietic progenitor cells of transgenic mice with increased copper/zinc-superoxide dismutase activity are resistant to tumor necrosis factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

1 September 2018

Transgenic mice overexpressing human copper/zinc-superoxide dismutase (Cu/Zn SOD) are not resistant to endotoxic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394602

1 September 2018

Rescue from programmed cell death in leukemic and normal myeloid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Premature aging changes in neuromuscular junctions of transgenic mice with an extra human CuZnSOD gene: A model for tongue pathology in Down's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of 2',7'-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics of Down's syndrome: overexpression of transfected human Cu/Zn-superoxide dismutase gene and the consequent physiological changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired neurotransmitter uptake in PC12 cells overexpressing human Cu/Zn-superoxide dismutase--implication for gene dosage effects in Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ALS, SOD and peroxynitrite

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant mice, Cu,Zn superoxide dismutase, and motor neuron degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cloning of normal ?Mast? cells in tissue culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The toxicity of high-dose superoxide dismutase suggests that superoxide can both initiate and terminate lipid peroxidation in the reperfused heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for oxygen radicals as second messengers

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down's syndrome: Abnormal neuromuscular junction in tongue of transgenic mice with elevated levels of human Cu/Zn-superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor beta 1 and cancer chemotherapy compounds in myeloid leukemic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse trisomy 16 as an animal model of human trisomy 21 (Down syndrome): Production of viable trisomy 16 ↔ diploid mouse chimeras

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzyme function of copper, zinc superoxide dismutase as a free radical generator

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down's syndrome: morphological remodelling and increased complexity in the neuromuscular junction of transgenic CuZn-superoxide dismutase mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic effects of expression of human superoxide dismutase in bovine adrenocortical cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7588627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1995.TB00181.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7588627%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7588627%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7588627%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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