(Q37624476)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

review article

1 reference

title

Targeting insulin-like growth factor type 1 receptor in cancer therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Tiffany A Traina

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Maria Teresa Ionta

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Bruno Massidda

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

publication date

30 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

255-266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies

11 February 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11523-009-0123-Z

Inhibition of insulin-like growth factor-1 receptor signaling enhances growth-inhibitory and proapoptotic effects of gefitinib (Iressa) in human breast cancer cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11523-009-0123-Z

Clinical development of inhibitors of the insulin-like growth factor receptor in oncology

21 January 2018

1 reference

12 December 2020

Increased expression of insulin-like growth factor i is associated with Ara-C resistance in leukemia

1 reference

12 December 2020

Circulating insulin-like growth factor peptides and prostate cancer risk: a systematic review and meta-analysis

1 reference

12 December 2020

Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains

1 reference

12 December 2020

Phase I dose escalation study of the anti insulin-like growth factor-I receptor monoclonal antibody CP-751,871 in patients with refractory solid tumors

1 reference

12 December 2020

Clinical pharmacodynamic effects of the growth hormone receptor antagonist pegvisomant: implications for cancer therapy

1 reference

12 December 2020

Functional responses and in vivo anti-tumour activity of h7C10: a humanised monoclonal antibody with neutralising activity against the insulin-like growth factor-1 (IGF-1) receptor and insulin/IGF-1 hybrid receptors

1 reference

12 December 2020

Expression and distribution of insulin-like growth factor-1 receptor in human carcinomas

1 reference

12 December 2020

Developmental regulation of the rat insulin-like growth factor I receptor gene

1 reference

12 December 2020

Safety, pharmacokinetics, and pharmacodynamics of the insulin-like growth factor type 1 receptor inhibitor figitumumab (CP-751,871) in combination with paclitaxel and carboplatin

1 reference

12 December 2020

Insulin, insulin-like growth factors and neoplasia

1 reference

12 December 2020

Growth hormone (GH) receptor blockade with a PEG-modified GH (B2036-PEG) lowers serum insulin-like growth factor-I but does not acutely stimulate serum GH.

1 reference

12 December 2020

Growth hormone-releasing hormone (GHRH) antagonists inhibit the proliferation of androgen-dependent and -independent prostate cancers.

1 reference

12 December 2020

Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice

1 reference

12 December 2020

The prognostic role of loss of insulin-like growth factor-binding protein-3 expression in head and neck carcinogenesis

1 reference

12 December 2020

Phase I, pharmacokinetic and pharmacodynamic study of the anti-insulinlike growth factor type 1 Receptor monoclonal antibody CP-751,871 in patients with multiple myeloma

1 reference

12 December 2020

Elevated serum insulin-like growth factor (IGF)-II and IGF binding protein-2 in patients with colorectal cancer

1 reference

12 December 2020

Circulating Insulin-Like Growth Factor-I and Binding Protein-3 and the Risk of Breast Cancer

1 reference

12 December 2020

Development of the monoclonal antibody figitumumab, targeting the insulin-like growth factor-1 receptor, for the treatment of patients with non-small-cell lung cancer

1 reference

12 December 2020

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

1 reference

12 December 2020

Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas

1 reference

12 December 2020

Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

1 reference

12 December 2020

Association of elevated IGFBP-1 with increased IGF-II concentration in patients with carcinoma of the liver

1 reference

12 December 2020

The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer.

1 reference

12 December 2020

Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation

1 reference

12 December 2020

Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells

1 reference

12 December 2020

Antitumor activity of the growth hormone receptor antagonist pegvisomant against human meningiomas in nude mice

1 reference

12 December 2020

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1 reference

12 December 2020

Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871.

1 reference

12 December 2020

Treatment of acromegaly with the GH receptor antagonist pegvisomant in clinical practice: safety and efficacy evaluation from the German Pegvisomant Observational Study

1 reference

12 December 2020

Mechanisms underlying lack of insulin-like growth factor-binding protein-3 expression in non-small-cell lung cancer.

1 reference

12 December 2020

Expression of insulin-like growth factor 1 receptor in primary breast cancer: immunohistochemical analysis

1 reference

12 December 2020

A recombinant humanized anti-insulin-like growth factor receptor type I antibody (h7C10) enhances the antitumor activity of vinorelbine and anti-epidermal growth factor receptor therapy against human cancer xenografts

1 reference

12 December 2020

Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

1 reference

12 December 2020

Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program

1 reference

12 December 2020

A humanised anti-IGF-1R monoclonal antibody (AVE1642) enhances Bortezomib-induced apoptosis in myeloma cells lacking CD45.

1 reference

12 December 2020

Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

1 reference

12 December 2020

Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling

1 reference

12 December 2020

Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer

1 reference

12 December 2020

An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation

1 reference

12 December 2020

Targeting insulin and insulin-like growth factor signalling in oncology

1 reference

12 December 2020

Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition

1 reference

12 December 2020

Structure of apo, unactivated insulin-like growth factor-1 receptor kinase at 1.5 Å resolution

1 reference

12 December 2020

Targeted therapies in Ewing's sarcoma.

1 reference

12 December 2020

Analysis of gene expression profiles associated with cisplatin resistance in human ovarian cancer cell lines and tissues using cDNA microarray.

1 reference

12 December 2020

Insulin-like growth factors and neoplasia.

1 reference

12 December 2020

Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.

1 reference

12 December 2020

Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib

1 reference

12 December 2020

Mortality and serum insulin-like growth factor (IGF)-I and IGF binding protein 3 concentrations.

1 reference

12 December 2020

Insulin-like growth factors and insulin-like growth factor-binding proteins in relation to disease status and incidence of hypoglycaemia in patients with a gastrointestinal stromal tumour

1 reference

12 December 2020

Growth inhibition of human prostate cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors

1 reference

12 December 2020

The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth

1 reference

12 December 2020

IMC-A12, a human IgG1 monoclonal antibody to the insulin-like growth factor I receptor

1 reference

12 December 2020

10.1007/S11523-009-0123-Z

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19876700%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference