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Immunoglobulin gene transcription ceases upon deletion of a distant enhancer.
scientific article published on December 1995
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Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
title
Immunoglobulin gene transcription ceases upon deletion of a distant enhancer
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
author name string
R Lieberson
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
J Ong
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
X Shi
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
L A Eckhardt
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
language of work or name
English
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publication date
1 December 1995
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
volume
14
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
issue
24
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
page(s)
6229-6238
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
cites work
NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3' alpha enhancer at early stages of B-cell differentiation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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23 August 2017
The immunoglobulin heavy chain locus contains another B-cell-specific 3' enhancer close to the alpha constant region
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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23 August 2017
An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the beta-globin locus control region
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23 August 2017
Identification of 3' alpha-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation
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23 August 2017
Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity
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23 August 2017
Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation
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23 August 2017
Expression of immunoglobulin heavy chain at a high level in the absence of a proposed immunoglobulin enhancer element in cis
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23 August 2017
Products of a reciprocal chromosome translocation involving the c-myc gene in a murine plasmacytoma
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23 August 2017
The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene
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23 August 2017
Mouse immunoglobulin genes: a bacterial plasmid containing the entire coding sequence for a pre-γ 2a heavy chain
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23 August 2017
Rate of somatic mutation in immunoglobulin production by mouse myeloma cells
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23 August 2017
Synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells. I. Adaptation of the Merwin plasma cell tumor-11 to culture, cloning, and characterization of gamma globulin subunits
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23 August 2017
Evidence for transient requirement of the IgH enhancer
1 reference
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23 August 2017
Deletion of a B-cell-specific enhancer affects transfected, but not endogenous, immunoglobulin heavy-chain gene expression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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23 August 2017
Unequal sister chromatid exchange. A mechanism affecting Ig gene arrangement and expression
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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23 August 2017
Independent immunoglobulin class-switch events occurring in a single myeloma cell line
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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23 August 2017
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
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23 August 2017
DNA rearrangement causes a high rate of spontaneous mutation at the immunoglobulin heavy-chain locus of a mouse myeloma cell line
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23 August 2017
Myeloma mutant with a novel 3' flanking region: loss of normal sequence and insertion of repetitive elements leads to decreased transcription but normal processing of the alpha heavy-chain gene products
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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23 August 2017
Homologous recombination can restore normal immunoglobulin production in a mutant hybridoma cell line
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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23 August 2017
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
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PubMed Central
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23 August 2017
Nuclear matrix attachment occurs in several regions of the IgH locus
1 reference
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PubMed Central
reference URL
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23 August 2017
An enhancer at the 3' end of the mouse immunoglobulin heavy chain locus
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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23 August 2017
Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting
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23 August 2017
Activation of cellular oncogenes in hemopoietic cells by chromosome translocation
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14 September 2017
Electroporation in biology: methods, applications, and instrumentation
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14 September 2017
The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells
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14 September 2017
Linkage analysis using somatic cell hybrids
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PubMed Central
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14 September 2017
V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer
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PubMed Central
reference URL
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28 September 2017
Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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28 September 2017
Constitutively expressed Oct-2 prevents immunoglobulin gene silencing in myeloma × T cell hybrids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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28 September 2017
Characterization of immunoglobulin enhancer deletions in murine plasmacytomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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28 September 2017
Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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25 June 2018
DNA regions flanking the mouse Ig 3' alpha enhancer are differentially methylated and DNAase I hypersensitive during B cell differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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25 June 2018
Deletion of the IgH enhancer does not reduce immunoglobulin heavy chain production of a hybridoma IgD class switch variant
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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25 June 2018
Extinction of expression of the translocated myc gene in somatic cell hybrids between mouse myeloma and L-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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25 June 2018
Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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25 June 2018
Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
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1 September 2018
Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
retrieved
1 September 2018
A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
retrieved
1 September 2018
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
retrieved
1 September 2018
The mouse IgH 3'-enhancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394747
retrieved
1 September 2018
5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8557042
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A class switch control region at the 3′ end of the immunoglobulin heavy chain locus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8557042
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Lipopolysaccharide-dependent transactivation of the temporally regulated immunoglobulin heavy chain 3' enhancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8557042
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/J.1460-2075.1995.TB00313.X
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
PMC publication ID
394747
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
PubMed publication ID
8557042
1 reference
stated in
Europe PubMed Central
PMC publication ID
394747
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8557042%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 October 2019
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