(Q37629201)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19896944%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

review article

1 reference

title

Eukaryotic and archaeal translation initiation factor 2: a heterotrimeric tRNA carrier (English)

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11 February 2020

3

1 reference

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11 February 2020

author name string

Emmanuelle Schmitt

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19896944%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Marie Naveau

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19896944%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

1 January 2010

1 reference

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11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19896944%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

584

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19896944%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19896944%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

405-412

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Protein Initiation in Eukaryotes: Formation and Function of a Ternary Complex Composed of a Partially Purified Ribosomal Factor, Methionyl Transfer RNA f , and Guanosine Triphosphate

11 February 2020

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1 reference

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GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae

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Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP.

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Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation

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Regulation of GTP hydrolysis prior to ribosomal AUG selection during eukaryotic translation initiation

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Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo

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Ancient ciphers: translation in Archaea

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Archaeal translation initiation revisited: the initiation factor 2 and eukaryotic initiation factor 2B alpha-beta-delta subunit families

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Solution structure of human initiation factor eIF2alpha reveals homology to the elongation factor eEF1B

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Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha

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Structural switch of the gamma subunit in an archaeal aIF2 alpha gamma heterodimer.

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In vitro phosphorylation of initiation factor 2 alpha (aIF2 alpha) from hyperthermophilic archaeon Pyrococcus horikoshii OT3.

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Specific interaction of eukaryotic translation initiation factor 5 (eIF5) with the beta-subunit of eIF2

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Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.

21 January 2018

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Structure of the archaeal translation initiation factor aIF2 from Methanobacterium thermoautotrophicum: Implications for translation initiation

21 January 2018

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Structure of archaeal translational initiation factor 2 betagamma-GDP reveals significant conformational change of the beta-subunit and switch 1 region

21 January 2018

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Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states

21 January 2018

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Translation initiation at non-AUG codons mediated by weakened association of eukaryotic initiation factor (eIF) 2 subunits.

21 January 2018

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The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors.

21 January 2018

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Crystal structure of the intact archaeal translation initiation factor 2 demonstrates very high conformational flexibility in the alpha- and beta-subunits

21 January 2018

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Intersubunit and interprotein interactions of alpha- and beta-subunits of human eIF2: Effect of phosphorylation.

21 January 2018

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Interaction of recombinant human eIF2 subunits with eIF2B and eIF2alpha kinases

21 January 2018

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X-ray structure of translation initiation factor eIF2gamma: implications for tRNA and eIF2alpha binding

21 January 2018

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New insights into the interactions of the translation initiation factor 2 from archaea with guanine nucleotides and initiator tRNA

21 January 2018

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The guanine nucleotide-binding switch in three dimensions

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Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex

21 January 2018

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Crystal structure of active elongation factor Tu reveals major domain rearrangements

21 January 2018

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Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog

21 January 2018

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GTP-dependent recognition of the methionine moiety on initiator tRNA by translation factor eIF2.

21 January 2018

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Functional molecular mapping of archaeal translation initiation factor 2.

21 January 2018

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Removal of beta subunit of the eukaryotic polypeptide chain initiation factor 2 by limited proteolysis

21 January 2018

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Rabbit reticulocyte initiation factor 2 contains two polypeptide chains of molecular weights 48,000 and 38,000

21 January 2018

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Affinity labeling of eukaryotic initiation factor 2 and elongation factor 1 alpha beta gamma with GTP analogs

21 January 2018

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An alpha subunit-deficient form of eukaryotic protein synthesis initiation factor eIF-2 from rabbit reticulocyte lysate and its activity in ternary complex formation

21 January 2018

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Biochemical analysis of the eIF2beta gamma complex reveals a structural function for eIF2alpha in catalyzed nucleotide exchange

21 January 2018

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tRNomics: analysis of tRNA genes from 50 genomes of Eukarya, Archaea, and Bacteria reveals anticodon-sparing strategies and domain-specific features

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Yeast initiator tRNA identity elements cooperate to influence multiple steps of translation initiation

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Thermodynamic analysis reveals that GTP binding affects the interaction between the alpha- and gamma-subunits of translation initiation factor 2.

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21 January 2018

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21 January 2018

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21 January 2018

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

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Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses

21 January 2018

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Translational regulation of GCN4 and the general amino acid control of yeast

21 January 2018

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Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p

21 January 2018

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eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA.

21 January 2018

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

21 January 2018

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

21 January 2018

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Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2

21 January 2018

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Translational control of long-lasting synaptic plasticity and memory

21 January 2018

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Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.

21 January 2018

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The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores

21 January 2018

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Regulation of translation initiation in eukaryotes: mechanisms and biological targets

21 January 2018

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Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon

21 January 2018

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Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange.

21 January 2018

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Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors

21 January 2018

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Structure and interactions of the translation initiation factor eIF1

21 January 2018

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Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex

21 January 2018

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Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

21 January 2018

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