(Q37629622)

21 August 2017

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title

A spectrum of gene regulatory phenomena at mammalian beta-globin gene loci (English)

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21 August 2017

George Fromm

1

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21 August 2017

Michael Bulger

series ordinal

2

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21 August 2017

publication date

1 October 2009

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Biochemistry and Cell Biology

21 August 2017

published in

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21 August 2017

volume

87

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21 August 2017

issue

5

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21 August 2017

page(s)

781-790

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21 August 2017

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Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region.

21 January 2018

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Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription

21 January 2018

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CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation

21 January 2018

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Developmental stage-specific epigenetic control of human beta-globin gene expression is potentiated in hematopoietic progenitor cells prior to their transcriptional activation

21 January 2018

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Lineage-specific activators affect beta-globin locus chromatin in multipotent hematopoietic progenitors

21 January 2018

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Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes

21 January 2018

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A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus

21 January 2018

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Hypersensitive site 2 specifies a unique function within the human beta-globin locus control region to stimulate globin gene transcription

21 January 2018

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Coregulation of GATA factors by the Friend of GATA (FOG) family of multitype zinc finger proteins

21 January 2018

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BCL11A represses HBG transcription in K562 cells

21 January 2018

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The role of transcriptional activator GATA-1 at human beta-globin HS2

21 January 2018

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Spatial organization of gene expression: the active chromatin hub.

21 January 2018

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Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.

21 January 2018

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The active spatial organization of the beta-globin locus requires the transcription factor EKLF

21 January 2018

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Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development

21 January 2018

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Synergistic and additive properties of the beta-globin locus control region (LCR) revealed by 5'HS3 deletion mutations: implication for LCR chromatin architecture

21 January 2018

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Controlling the double helix

21 January 2018

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Combinatorial effects of four histone modifications in transcription and differentiation

21 January 2018

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Position-independent, high-level expression of the human beta-globin gene in transgenic mice

21 January 2018

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Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death

21 January 2018

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A global role for EKLF in definitive and primitive erythropoiesis

21 January 2018

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CpG hypomethylation in a large domain encompassing the embryonic beta-like globin genes in primitive erythrocytes

21 January 2018

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Deletion of the core region of 5' HS2 of the mouse beta-globin locus control region reveals a distinct effect in comparison with human beta-globin transgenes

21 January 2018

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Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain

21 January 2018

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Functional selectivity of recombinant mammalian SWI/SNF subunits

21 January 2018

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A common precursor for primitive erythropoiesis and definitive haematopoiesis

21 January 2018

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Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequences

21 January 2018

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Nucleosome and transcription activator antagonism at human beta-globin locus control region DNase I hypersensitive sites

21 January 2018

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Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation.

21 January 2018

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"Maturational" globin switching in primary primitive erythroid cells

21 January 2018

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Reconstitution of human beta-globin locus control region hypersensitive sites in the absence of chromatin assembly.

21 January 2018

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DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

21 January 2018

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Individual LCR hypersensitive sites cooperate to generate an open chromatin domain spanning the human beta-globin locus

21 January 2018

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Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitment

21 January 2018

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Developmental- and differentiation-specific patterns of human gamma- and beta-globin promoter DNA methylation

21 January 2018

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Activation of the beta globin locus by transcription factors and chromatin modifiers

21 January 2018

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A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.

21 January 2018

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A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins

21 January 2018

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The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis

21 January 2018

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Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes

21 January 2018

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The histone acetyltransferase PCAF associates with actin and hnRNP U for RNA polymerase II transcription

21 January 2018

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Active genes dynamically colocalize to shared sites of ongoing transcription

21 January 2018

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Regulation of erythroid Krüppel-like factor (EKLF) transcriptional activity by phosphorylation of a protein kinase casein kinase II site within its interaction domain.

21 January 2018

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Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

21 January 2018

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Autonomous developmental control of human embryonic globin gene switching in transgenic mice.

21 January 2018

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Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

21 January 2018

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Activation of beta-major globin gene transcription is associated with recruitment of NF-E2 to the beta-globin LCR and gene promoter

21 January 2018

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The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation

21 January 2018

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Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the beta-globin locus

21 January 2018

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Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

21 January 2018

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Control of globin gene expression during development and erythroid differentiation

21 January 2018

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Looping and interaction between hypersensitive sites in the active beta-globin locus

21 January 2018

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Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1.

21 January 2018

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Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin

21 January 2018

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Phenotype-genotype relationships in monogenic disease: lessons from the thalassaemias.

21 January 2018

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Chromosomal subunits in active genes have an altered conformation

21 January 2018

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Sox6 directly silences epsilon globin expression in definitive erythropoiesis

21 January 2018

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Histone acetylation at the human beta-globin locus changes with developmental age.

21 January 2018

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Heme induces ubiquitination and degradation of the transcription factor Bach1

21 January 2018

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Site-specific acetylation by p300 or CREB binding protein regulates erythroid Krüppel-like factor transcriptional activity via its interaction with the SWI-SNF complex

21 January 2018

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Human γ-globin genes silenced independently of other genes in the β-globin locus

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O09-048

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21 August 2017

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