(Q37634171)

English

Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure

scientific article published on July 1994

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

author name string

P Leboulch

1

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23 October 2019

G M Huang

2

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23 October 2019

R K Humphries

3

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23 October 2019

Y H Oh

4

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23 October 2019

C J Eaves

5

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23 October 2019

D Y Tuan

6

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23 October 2019

I M London

7

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Europe PubMed Central

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23 October 2019

language of work or name

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publication date

1 July 1994

1 reference

Europe PubMed Central

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23 October 2019

The EMBO Journal

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

13

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

13

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

3065-3076

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

The DNA sequence of the 5' flanking region of the human beta-globin gene: evolutionary conservation and polymorphic differences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Self-renewal of hemopoietic stem cells during mixed colony formation in vitro

1 reference

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23 August 2017

Mapping of DNase I-hypersensitive sites in the upstream DNA of human embryonic epsilon-globin gene in K562 leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

The "beta-like-globin" gene domain in human erythroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

A developmentally stable chromatin structure in the human beta-globin gene cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Expression of the human beta-globin gene following retroviral-mediated transfer into multipotential hematopoietic progenitors of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Design of retrovirus vectors for transfer and expression of the human beta-globin gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Molecular analysis of the human beta-globin locus activation region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Improved retroviral vectors for gene transfer and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Retrovirus-mediated gene transfer to purified hemopoietic stem cells with long-term lympho-myelopoietic repopulating ability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Detailed analysis of the site 3 region of the human beta-globin dominant control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

The beta-globin dominant control region: hypersensitive site 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Exon definition may facilitate splice site selection in RNAs with multiple exons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Hypersensitive site 4 of the human beta globin locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Combinatorial splicing of exon pairs by two-site binding of U1 small nuclear ribonucleoprotein particle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Characterization of large deletions occurring during a single round of retrovirus vector replication: novel deletion mechanism involving errors in strand transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Retroviral Recombination and Reverse Transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Specificities involved in the initiation of retroviral plus-strand DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

A 36-base-pair core sequence of locus control region enhances retrovirally transferred human beta-globin gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Proliferation of totipotent hematopoietic stem cells in vitro with retention of long-term competitive in vivo reconstituting ability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

23 August 2017

Characterization of a DNA binding activity in DNAse I hypersensitive site 4 of the human globin locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

14 September 2017

The basic science of gene therapy

1 reference

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28 September 2017

Establishment and characterization of BALB/c lymphoma lines with B cell properties

1 reference

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28 September 2017

A human beta-globin gene fused to the human beta-globin locus control region is expressed at high levels in erythroid cells of mice engrafted with retrovirus-transduced hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395197

25 June 2018

A transplantable myelomonocytic leukemia in BALB-c mice: cytology, karyotype, and muramidase content

1 reference

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25 June 2018

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice.

1 reference

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25 June 2018

Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

1 reference

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25 June 2018

Lineage-specific expression of a human beta-globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells

1 reference

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25 June 2018

Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells

1 reference

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Deletion in a recombinant retroviral vector resulting from a cryptic splice donor signal in the Moloney leukemia virus envelope gene

1 reference

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25 June 2018

Unexpected point mutations activate cryptic 3' splice sites by perturbing a natural secondary structure within a yeast intron

1 reference

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25 June 2018

Mechanisms of Alternative Pre-mRNA Splicing

1 reference

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25 June 2018

Developmental potential and dynamic behavior of hematopoietic stem cells.

1 reference

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1 September 2018

The regulated expression of β-globin genes introduced into mouse erythroleukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A minimal intron length but no specific internal sequence is required for splicing the large rabbit beta-globin intron

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal hematopoiesis demonstrated by X-linked DNA polymorphisms after allogeneic bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A normal level of beta-globin expression in erythroid cells after retroviral cells transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/8039501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1994.TB06605.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8039501%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

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