(Q37634359)

21 August 2017

KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9. (English)

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21 August 2017

1 reference

X Wang

1

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21 August 2017

H Lu

2

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21 August 2017

A M Urvalek

3

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21 August 2017

T Li

4

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21 August 2017

L Yu

5

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21 August 2017

J Lamar

6

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21 August 2017

C M DiPersio

7

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21 August 2017

P J Feustel

8

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21 August 2017

J Zhao

9

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21 August 2017

language of work or name

English

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publication date

13 December 2010

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21 August 2017

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21 August 2017

30

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21 August 2017

1901-1911

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21 August 2017

16

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https://scigraph.springernature.com/pub.10.1038/onc.2010.563

21 August 2017

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Signal transduction by focal adhesion kinase in cancer

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An immortalization-dependent switch in integrin function up-regulates MMP-9 to enhance tumor cell invasion

23 August 2017

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A network of Krüppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo

23 August 2017

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Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells

23 August 2017

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Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion

23 August 2017

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23 August 2017

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Regulation of matrix metalloproteinase gene expression

23 August 2017

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MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation

23 August 2017

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KLF8 transcription factor participates in oncogenic transformation

23 August 2017

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Circulating tumor cells, disease progression, and survival in metastatic breast cancer

23 August 2017

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Expression of inappropriate cadherins by epithelial tumor cells promotes endocytosis and degradation of E-cadherin via competition for p120(ctn).

23 August 2017

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Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo

23 August 2017

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Matrix metalloproteinase inhibitors suppress transforming growth factor-beta-induced subcapsular cataract formation

23 August 2017

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Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

23 August 2017

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A functional screen for Krüppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element

23 August 2017

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Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

23 August 2017

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Multiple connections link FAK to cell motility and invasion

23 August 2017

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Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner

23 August 2017

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Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression

23 August 2017

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23 August 2017

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

23 August 2017

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Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription

23 August 2017

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Activation of KLF8 transcription by focal adhesion kinase in human ovarian epithelial and cancer cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

KLF8 recruits the p300 and PCAF co-activators to its amino terminal activation domain to activate transcription

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Therapeutic intervention of experimental breast cancer bone metastasis by indole-3-carbinol in SCID-human mouse model

14 September 2017

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Connexins act as tumor suppressors in three-dimensional mammary cell organoids by regulating differentiation and angiogenesis

14 September 2017

1 reference

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Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin

14 September 2017

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A versatile tool for conditional gene expression and knockdown

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Ischemia-induced cleavage of cadherins in NRK cells requires MT1-MMP (MMP-14).

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Alpha3beta1 integrin regulates MMP-9 mRNA stability in immortalized keratinocytes: a novel mechanism of integrin-mediated MMP gene expression.

14 September 2017

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p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

The Krüppel traffic report: cooperative signals direct KLF8 nuclear transport

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

A unique sequence in the N-terminal regulatory region controls the nuclear localization of KLF8 by cooperating with the C-terminal zinc-fingers

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Sumoylation delimits KLF8 transcriptional activity associated with the cell cycle regulation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

KLF8 sets the pace for the cell cycle through interactions with p300 and PCAF.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

New insights into KLF8-mediated transactivation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Upregulation of MMPs by soluble E-cadherin in human lung tumor cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3952074

Membrane type 1-matrix metalloproteinase expression is regulated by E-cadherin through the suppression of mitogen-activated protein kinase cascade

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2010.563

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.563

1 reference

21 August 2017

1 reference

21 August 2017

1 reference