(Q37638199)

21 August 2017

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title

Tissue-mediated control of immunopathology in coeliac disease (English)

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21 August 2017

Bana Jabri

1

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21 August 2017

Ludvig M Sollid

series ordinal

2

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21 August 2017

publication date

1 December 2009

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Nature Reviews Immunology

21 August 2017

published in

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21 August 2017

volume

9

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21 August 2017

issue

12

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21 August 2017

page(s)

858-870

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https://scigraph.springernature.com/pub.10.1038/nri2670

21 August 2017

exact match

0 references

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The immune system evolved to discriminate infectious nonself from noninfectious self

31 March 2020

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Friendly and dangerous signals: is the tissue in control?

31 March 2020

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T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal

31 March 2020

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Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

31 March 2020

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

31 March 2020

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Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

31 March 2020

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Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia

31 March 2020

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IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway

31 March 2020

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Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer

31 March 2020

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HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7.

31 March 2020

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Concordance, disease progression, and heritability of coeliac disease in Italian twins

31 March 2020

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A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

31 March 2020

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Newly identified genetic risk variants for celiac disease related to the immune response

31 March 2020

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Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

31 March 2020

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Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease

31 March 2020

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Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease

31 March 2020

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Shared and distinct genetic variants in type 1 diabetes and celiac disease

31 March 2020

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Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

31 March 2020

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

31 March 2020

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Structural basis for gluten intolerance in celiac sprue

31 March 2020

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The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase

31 March 2020

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Structure of celiac disease-associated HLA-DQ8 and non-associated HLA-DQ9 alleles in complex with two disease-specific epitopes

31 March 2020

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Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

31 March 2020

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Gliadin activates HLA class I-restricted CD8+ T cells in celiac disease intestinal mucosa and induces the enterocyte apoptosis

31 March 2020

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In siblings of celiac children, rectal gluten challenge reveals gluten sensitization not restricted to celiac HLA.

31 March 2020

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Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease

31 March 2020

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A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease.

31 March 2020

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Growth factor-like activity of gliadin, an alimentary protein: implications for coeliac disease

31 March 2020

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Gliadin regulates the NK-dendritic cell cross-talk by HLA-E surface stabilization

31 March 2020

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Gliadin peptides activate blood monocytes from patients with celiac disease

31 March 2020

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Wheat gluten causes dendritic cell maturation and chemokine secretion.

31 March 2020

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Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3

31 March 2020

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Post-translational protein modifications in antigen recognition and autoimmunity

31 March 2020

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Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury

31 March 2020

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The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease

31 March 2020

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The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides

31 March 2020

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The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses

31 March 2020

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On the HLA-DQ(α1*0501, β1*0201)-associated susceptibility in celiac disease: A possible gene dosage effect ofDQB1*0201

31 March 2020

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HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease

31 March 2020

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HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease

31 March 2020

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Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation

31 March 2020

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HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

31 March 2020

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Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

31 March 2020

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A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

31 March 2020

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Restricted islet-cell reactive T cell repertoire of early pancreatic islet infiltrates in NOD mice

31 March 2020

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Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease

31 March 2020

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Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation

31 March 2020

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The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases

31 March 2020

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Unique peptide binding characteristics of the disease-associated DQ(alpha 1*0501, beta 1*0201) vs the non-disease-associated DQ(alpha 1*0201, beta 1*0202) molecule

31 March 2020

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T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

31 March 2020

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Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

31 March 2020

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Peripheral deletion of antigen-reactive T cells in oral tolerance.

31 March 2020

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Retinoic acid: an educational "vitamin elixir" for gut-seeking T cells

31 March 2020

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The yin and yang of intestinal epithelial cells in controlling dendritic cell function

31 March 2020

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31 March 2020

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Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls

31 March 2020

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Selective expansion of intraepithelial lymphocytes expressing the HLA-E–specific natural killer receptor CD94 in celiac disease

31 March 2020

1 reference

Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease

31 March 2020

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Interleukin 15 mediates epithelial changes in celiac disease

31 March 2020

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The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

31 March 2020

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Dendritic cells and cytokines in human inflammatory and autoimmune diseases

31 March 2020

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Role of interferon alpha in promoting T helper cell type 1 responses in the small intestine in coeliac disease

31 March 2020

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Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease

31 March 2020

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A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells

31 March 2020

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Onset of coeliac disease during treatment with interferon for chronic hepatitis C.

31 March 2020

1 reference

Rotavirus and celiac disease: clues to the pathogenesis and perspectives on prevention

31 March 2020

1 reference

Inhibition of TGF-β Signaling by IL-15: A New Role for IL-15 in the Loss of Immune Homeostasis in Celiac Disease

31 March 2020

1 reference

Interleukin 21 contributes to the mucosal T helper cell type 1 response in coeliac disease

31 March 2020

1 reference

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4+ T Lymphocytes

31 March 2020

1 reference

Expression of nonclassical class I molecules by intestinal epithelial cells

31 March 2020

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IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity

31 March 2020

1 reference

Autoantibodies in coeliac disease: tissue transglutaminase--guilt by association?

31 March 2020

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Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease

31 March 2020

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Fcgamma receptors as regulators of immune responses

31 March 2020

1 reference

Chronic intestinal graft-versus-host disease: clinical, histological and immunohistochemical analysis of 17 children

31 March 2020

1 reference

Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue')

31 March 2020

1 reference

Numbers of T cell receptor (TCR) alpha beta+ but not of TcR gamma delta+ intraepithelial lymphocytes correlate with the grade of villous atrophy in coeliac patients on a long term normal diet.

31 March 2020

1 reference

HLA-DQ determines the response to exogenous wheat proteins: a model of gluten sensitivity in transgenic knockout mice

31 March 2020

1 reference

Resistance to Celiac Disease in Humanized HLA-DR3-DQ2-Transgenic Mice Expressing Specific Anti-Gliadin CD4+ T Cells

31 March 2020

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Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes

31 March 2020

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NKG2D recognition mediates Toll-like receptor 3 signaling-induced breakdown of epithelial homeostasis in the small intestines of mice

31 March 2020

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NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment

31 March 2020

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Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease.

31 March 2020

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TCR specificity dictates CD94/NKG2A expression by human CTL.

31 March 2020

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Reprogramming of CTLs into natural killer-like cells in celiac disease

31 March 2020

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Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15.

31 March 2020

1 reference

5-Lipoxygenase: Cellular Biology and Molecular Pharmacology

31 March 2020

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Intraepithelial T cells of the TcR gamma/delta+ CD8- and V delta 1/J delta 1+ phenotypes are increased in coeliac disease

31 March 2020

1 reference

T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gamma delta T cells

31 March 2020

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Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity

31 March 2020

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Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease.

31 March 2020

1 reference

Increase in gamma/delta T cell receptor bearing lymphocytes in normal small bowel mucosa in latent coeliac disease

31 March 2020

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A Structural basis for the association of DAP12 with mouse, but not human, NKG2D

31 March 2020

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Refractory coeliac disease

31 March 2020

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Abnormal intestinal intraepithelial lymphocytes in refractory sprue

31 March 2020

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Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells.

31 March 2020

1 reference

Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis

31 March 2020

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NKG2D blockade prevents autoimmune diabetes in NOD mice

31 March 2020

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Development of type 1 diabetes mellitus during interferon alfa therapy for chronic HCV hepatitis

31 March 2020

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Thyroid autoimmune disorders in patients with chronic hepatitis C before and during interferon-alpha therapy

31 March 2020

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Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients

31 March 2020

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T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8.

31 March 2020

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Detecting shared pathogenesis from the shared genetics of immune-related diseases

31 March 2020

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Identification of tissue transglutaminase as the autoantigen of celiac disease

31 March 2020

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Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies

31 March 2020

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Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis?

31 March 2020

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Transglutaminases: crosslinking enzymes with pleiotropic functions

31 March 2020

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T cells from celiac disease lesions recognize gliadin epitopes deamidated in situ by endogenous tissue transglutaminase

31 March 2020

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Specificity of tissue transglutaminase explains cereal toxicity in celiac disease

31 March 2020

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A quantitative analysis of transglutaminase 2-mediated deamidation of gluten peptides: implications for the T-cell response in celiac disease

31 March 2020

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CTLA-4 gene polymorphism is associated with predisposition to coeliac disease

31 March 2020

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Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling

31 March 2020

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NKG2 receptor-mediated regulation of effector CTL functions in the human tissue microenvironment.

31 March 2020

1 reference

12 December 2020

Oral tolerance in humans. T cell but not B cell tolerance after antigen feeding

1 reference

12 December 2020

Classification of intractable diarrhea in infancy using clinical and immunohistological criteria

1 reference

12 December 2020

HLA in coeliac disease: Unravelling the complex genetics of a complex disorder

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12 December 2020

Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls

1 reference

12 December 2020

Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI2670

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Dimensions Publication ID

21 August 2017

1019656450

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