(Q37639314)

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A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.

scientific article published on December 1994

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30 October 2019

A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation (English)

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30 October 2019

African clawed frog

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M Dasso

1

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30 October 2019

T Seki

2

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30 October 2019

Y Azuma

3

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30 October 2019

T Ohba

4

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30 October 2019

T Nishimoto

5

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30 October 2019

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1 December 1994

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30 October 2019

The EMBO Journal

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30 October 2019

13

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30 October 2019

23

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30 October 2019

5732-5744

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30 October 2019

GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

The Saccharomyces cerevisiae SDC25 C-domain gene product overcomes the dominant inhibitory activity of Ha-Ras Asn-17.

1 reference

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23 August 2017

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

A G protein involved in nucleocytoplasmic transport: the role of Ran

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Roles of cytosol and cytoplasmic particles in nuclear envelope assembly and sperm pronuclear formation in cell-free preparations from amphibian eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

A trypsin-sensitive receptor on membrane vesicles is required for nuclear envelope formation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Nuclear import can be separated into distinct steps in vitro: nuclear pore binding and translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Cloning of Xenopus RCC1 cDNA, a homolog of the human RCC1 gene: complementation of tsBN2 mutation and identification of the product.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

The GTPase superfamily: a conserved switch for diverse cell functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Systems for the study of nuclear assembly, DNA replication, and nuclear breakdown in Xenopus laevis egg extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

RCC1, a regulator of mitosis, is essential for DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

23 August 2017

Effects of mutant Ran/TC4 proteins on cell cycle progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

6 September 2017

Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

6 September 2017

Amino acid residues in the Ras-like GTPase Rab3A that specify sensitivity to factors that regulate the GTP/GDP cycling of Rab3A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

6 September 2017

RCC1 in the cell cycle: the regulator of chromosome condensation takes on new roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

28 September 2017

A fission yeast RCC1-related protein is required for the mitosis to interphase transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

28 September 2017

Assembly of spaced chromatin promoted by DNA synthesis in extracts from Xenopus eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

28 September 2017

Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

28 September 2017

Prp20, the Saccharomyces cerevisiae homolog of the regulator of chromosome condensation, RCC1, interacts with double-stranded DNA through a multi-component complex containing GTP-binding proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

25 June 2018

Chromatin transitions during early Xenopus embryogenesis: changes in histone H4 acetylation and in linker histone type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

25 June 2018

Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

25 June 2018

Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: studies in Xenopus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

25 June 2018

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

25 June 2018

Premature of chromosome condensation in a ts DNA- mutant of BHK cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

25 June 2018

Absence of somatic histone H1 in oocytes and preblastula embryos of Xenopus laevis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

1 September 2018

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395539

1 September 2018

A family of proteins that stabilize the Ran/TC4 GTPase in its GTP-bound conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7988569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthesis of protein(S) for chromosome condensation may be regulated by a post-transcriptional mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/7988569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the nuclear lamina composition during early development of Xenopus laevis

1 reference

https://pubmed.ncbi.nlm.nih.gov/7988569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear reconstitution in vitro: stages of assembly around protein-free DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/7988569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure to caffeine and suppression of DNA replication combine to stabilize the proteins and RNA required for premature mitotic events

1 reference

https://pubmed.ncbi.nlm.nih.gov/7988569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1994.TB06911.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7988569%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7988569%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7988569%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

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