(Q37641746)

21 August 2017

1 reference

title

Cardiovascular effects of leptin (English)

1 reference

21 August 2017

1 reference

Gary Sweeney

1

1 reference

PubMed ID

19949425

21 August 2017

language of work or name

English

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publication date

1 December 2009

1 reference

Nature Reviews Cardiology

21 August 2017

1 reference

21 August 2017

7

1 reference

21 August 2017

1

1 reference

21 August 2017

22-29

1 reference

Echocardiographic assessment of cardiac function in diabetic db/db and transgenic db/db-hGLUT4 mice

21 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Adiposity of the heart, revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Decreased p110alpha catalytic activity accompanies increased myocyte apoptosis and cardiac hypertrophy in leptin deficient ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Protein kinase cascades in the regulation of cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Extracellular matrix profiles in the progression to heart failure. European Young Physiologists Symposium Keynote Lecture-Bratislava 2007.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Angiotensin-converting enzyme inhibition attenuates hypofibrinolysis and reduces cardiac perivascular fibrosis in genetically obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Cardiac remodeling in obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Unraveling the mechanisms linking obesity and heart failure: the role of adipokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Rat heart is a site of leptin production and action

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Adipocytokines and proinflammatory mediators from abdominal and epicardial adipose tissue in patients with coronary artery disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Epicardial fat: properties, function and relationship to obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Epicardial adipose tissue extent: relationship with age, body fat distribution, and coronaropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Clinical significance of epicardial fat measured using cardiac multislice computed tomography

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Influence of excess fat on cardiac morphology and function: study in uncomplicated obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Epicardial adipose tissue and insulin resistance in obese subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Aerobic exercise training reduces epicardial fat in obese men.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Effects of weight loss after bariatric surgery on epicardial fat measured using echocardiography

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Substantial changes in epicardial fat thickness after weight loss in severely obese subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Do cardiac and perivascular adipose tissue play a role in atherosclerosis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Perivascular fat: innocent bystander or active player in vascular disease?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin and mechanisms of endothelial dysfunction and cardiovascular disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Mature adipocytes and perivascular adipose tissue stimulate vascular smooth muscle cell proliferation: effects of aging and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin resistance and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin and cardiovascular disease: response to therapeutic interventions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Cardiac lipid accumulation associated with diastolic dysfunction in obese mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Effect of leptin on arterial thrombosis following vascular injury in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin and atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin as a potential treatment for obesity: progress to date

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Role of leptin in the cardiovascular and endocrine complications of metabolic syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Insulin resistance induces hyperleptinemia, cardiac contractile dysfunction but not cardiac leptin resistance in ventricular myocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Cardiac energy metabolism in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Stimulation of cardiac fatty acid oxidation by leptin is mediated by a nitric oxide-p38 MAPK-dependent mechanism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Distinct effects of short- and long-term leptin treatment on glucose and fatty acid uptake and metabolism in HL-1 cardiomyocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Uptake of long chain free fatty acids is selectively up-regulated in adipocytes of Zucker rats with genetic obesity and non-insulin-dependent diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Acute stimulation of glucose metabolism in mice by leptin treatment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Insulin-like effect of low-dose leptin on glucose transport in Langendorff rat hearts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Role of apoptosis in cardiovascular disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Apoptosis in myocytes in end-stage heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Apoptosis in the failing human heart

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Hypoxia-induced cleavage of caspase-3 and DFF45/ICAD in human failed cardiomyocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Matrix metalloproteinase-2 degrades the cytoskeletal protein α-actinin in peroxynitrite mediated myocardial injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Functional consequences of caspase activation in cardiac myocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin protects H9c2 rat cardiomyocytes from H2O2-induced apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin attenuates cardiac apoptosis after chronic ischaemic injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin, the obesity-associated hormone, exhibits direct cardioprotective effects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Lipotoxic heart disease in obese rats: implications for human obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

The cardioprotective actions of leptin are lost in the Zucker obese (fa/fa) rat.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Left ventricular remodelling: common process in patients with different primary myocardial disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Structural basis for heart failure. Ventricular remodeling and its pharmacological inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Cardiac hypertrophy: the good, the bad, and the ugly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Hypertrophy of the heart: a new therapeutic target?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

The obesity-associated peptide leptin induces hypertrophy in neonatal rat ventricular myocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin induces hypertrophy via endothelin-1-reactive oxygen species pathway in cultured neonatal rat cardiomyocytes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin and endothelin-1 mediated increased extracellular matrix protein production and cardiomyocyte hypertrophy in diabetic heart disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin-induced cardiomyocyte hypertrophy involves selective caveolae and RhoA/ROCK-dependent p38 MAPK translocation to nuclei

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin induces elongation of cardiac myocytes and causes eccentric left ventricular dilatation with compensation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin does not induce hypertrophy, cell cycle alterations, or production of MCP-1 in cultured rat and mouse cardiomyocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

A neutralizing leptin receptor antibody mitigates hypertrophy and hemodynamic dysfunction in the postinfarcted rat heart

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

The biochemical response of the heart to hypertension and exercise

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin signalling reduces the severity of cardiac dysfunction and remodelling after chronic ischaemic injury.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Cardiac remodeling and failure From molecules to man (Part II).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Cardiac remodeling and failure: from molecules to man (Part I).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Implications of myocardial matrix remodeling by adipokines in obesity-related heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Salutary effects of attenuation of angiotensin II on coronary perivascular fibrosis associated with insulin resistance and obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Reduced cardiac expression of plasminogen activator inhibitor 1 and transforming growth factor beta1 in obese Zucker rats by perindopril

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Improvement of chronic heart failure by dexamethasone is not associated with downregulation of leptin in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Inflammation in chronic heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Role of inflammation in the progression of heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Systemic inflammation in heart failure--the whys and wherefores

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Role of Toll like receptor signaling pathway in ischemic coronary artery disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin-dependent toll-like receptor expression and responsiveness in preadipocytes and adipocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Role of leptin in obesity-related hypertension

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Role of selective leptin resistance in diet-induced obesity hypertension.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin antagonist reverses hypertension caused by leptin overexpression, but fails to normalize obesity-related hypertension.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Hypertension and disrupted blood pressure circadian rhythm in type 2 diabetic db/db mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Obesity increases blood pressure, cerebral vascular remodeling, and severity of stroke in the Zucker rat.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Signaling components involved in leptin-induced amplification of the atherosclerosis-related properties of human monocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin-induced endothelial dysfunction in obesity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin receptors are expressed in coronary arteries, and hyperleptinemia causes significant coronary endothelial dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin-stimulated endothelial nitric-oxide synthase via an adenosine 5'-monophosphate-activated protein kinase/Akt signaling pathway is attenuated by interaction with C-reactive protein.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin resistance extends to the coronary vasculature in prediabetic dogs and provides a protective adaptation against endothelial dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Links between adipose tissue and thrombosis in the mouse

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin promotes aggregation of human platelets via the long form of its receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Absence of leptin resistance in platelets from morbidly obese individuals may contribute to the increased thrombosis risk in obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin-mediated activation of human platelets: involvement of a leptin receptor and phosphodiesterase 3A-containing cellular signaling complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRCARDIO.2009.224

Leptin attenuates hypoxia/reoxygenation-induced activation of the intrinsic pathway of apoptosis in rat H9c2 cells

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19949425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRCARDIO.2009.224

1 reference

21 August 2017

1 reference

PubMed ID

19949425