(Q37645697)

English

AICAR positively regulate glycogen synthase activity and LDL receptor expression through Raf-1/MEK/p42/44MAPK/p90RSK/GSK-3 signaling cascade

scientific article published on September 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

AICAR positively regulate glycogen synthase activity and LDL receptor expression through Raf-1/MEK/p42/44MAPK/p90RSK/GSK-3 signaling cascade (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

author name string

Hsiang-Ming Wang

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Sonya Mehta

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Rishipal Bansode

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Wei Huang

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Kamal D Mehta

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

language of work or name

0 references

publication date

1 September 2007

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Biochemical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

75

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

457-467

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Glycogen branches out: new perspectives on the role of glycogen metabolism in the integration of metabolic pathways.

1 reference

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23 August 2017

Selective repression of low-density lipoprotein receptor expression by SP600125: coupling of histone H3-Ser10 phosphorylation and Sp1 occupancy

1 reference

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23 August 2017

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

1 reference

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23 August 2017

Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

1 reference

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23 August 2017

AMP-activated protein kinase regulates gene expression by direct phosphorylation of nuclear proteins

1 reference

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23 August 2017

Role of mitogen-activated protein kinases and protein kinase C in regulating low-density lipoprotein receptor expression

1 reference

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23 August 2017

A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta

1 reference

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23 August 2017

Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway

1 reference

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23 August 2017

Role of AMP-activated protein kinase in mechanism of metformin action

1 reference

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23 August 2017

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3

1 reference

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23 August 2017

The AMP-activated protein kinase prevents ceramide synthesis de novo and apoptosis in astrocytes

1 reference

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23 August 2017

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

1 reference

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23 August 2017

Regulation of glycogen synthesis by amino acids in cultured human muscle cells.

1 reference

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23 August 2017

MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism

1 reference

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23 August 2017

A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

Troglitazone prevents and reverses dexamethasone induced insulin resistance on glycogen synthesis in 3T3 adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

New insights into the role and mechanism of glycogen synthase activation by insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

23 August 2017

Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

6 September 2017

Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

6 September 2017

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

14 September 2017

Increases in intracellular calcium dephosphorylate histone H3 at serine 10 in human hepatoma cells: potential role of protein phosphatase 2A-protein kinase CbetaII complex

1 reference

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14 September 2017

Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

14 September 2017

Dual regulation of glycogen synthase kinase-3beta by the alpha1A-adrenergic receptor

1 reference

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28 September 2017

Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

28 September 2017

Dissection of the protein phosphorylation cascades involved in insulin and growth factor action

1 reference

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28 September 2017

The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells

1 reference

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28 September 2017

Inhibition of glycogen synthase kinase-3 by insulin in cultured human skeletal muscle myoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

28 September 2017

Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

25 June 2018

5-Aminoimidazole-4-carboxamide riboside induces apoptosis in Jurkat cells, but the AMP-activated protein kinase is not involved.

1 reference

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25 June 2018

Amino acid- and lipid-induced insulin resistance in rat heart: molecular mechanisms

1 reference

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25 June 2018

The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells

1 reference

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25 June 2018

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

25 June 2018

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

Long-term AICAR administration and exercise prevents diabetes in ZDF rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside causes acute hepatic insulin resistance in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

AMP-activated protein kinase activation by AICAR increases both muscle fatty acid and glucose uptake in white muscle of insulin-resistant rats in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312663

1 September 2018

Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise

1 reference

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3 December 2018

The 5'-AMP-activated protein kinase inhibits the transcriptional stimulation by glucose in liver cells, acting through the glucose response complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel cis-acting element participating in maximal induction of the human low density lipoprotein receptor gene transcription in response to low cellular cholesterol levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin and exercise decrease glycogen synthase kinase-3 activity by different mechanisms in rat skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of glycogen synthase by hierarchal protein phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One-way cross-talk between p38(MAPK) and p42/44(MAPK). Inhibition of p38(MAPK) induces low density lipoprotein receptor expression through activation of the p42/44(MAPK) cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of multisite phosphorylation and inactivation of rabbit muscle glycogen synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMP-activated protein kinase counteracted the inhibitory effect of glucose on the phosphoenolpyruvate carboxykinase gene expression in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glucocorticoid-induced apoptosis with 5-aminoimidazole-4-carboxamide ribonucleoside, a cell-permeable activator of AMP-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human muscle glycogen resynthesis after exercise: insulin-dependent and -independent phases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17945190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BCP.2007.08.028

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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