(Q37657055)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016506%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

review article

1 reference

title

Mechanisms maintaining peripheral tolerance (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016506%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016506%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Daniel L Mueller

series ordinal

1

1 reference

21 August 2017

language of work or name

English

0 references

publication date

17 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016506%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016506%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016506%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016506%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

21-27

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016506%20AND%20SRC:MED&resulttype=core&format=json

Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

15 January 2020

cites work

1 reference

12 December 2020

Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

1 reference

12 December 2020

Langerhans cells are not required for the CD8 T cell response to epidermal self-antigens

1 reference

12 December 2020

Tolerance and autoimmunity in TCR transgenic mice specific for myelin basic protein.

1 reference

12 December 2020

CD4+ T cell tolerance to parenchymal self-antigens requires presentation by bone marrow-derived antigen-presenting cells

1 reference

12 December 2020

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

1 reference

12 December 2020

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1 reference

12 December 2020

CTLA-4 regulates induction of anergy in vivo

1 reference

12 December 2020

Treatment of murine lupus with CTLA4Ig

1 reference

12 December 2020

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self

1 reference

12 December 2020

Natural adjuvants: endogenous activators of dendritic cells

1 reference

12 December 2020

Checkpoints in lymphocyte development and autoimmune disease

1 reference

12 December 2020

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

1 reference

12 December 2020

Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node

1 reference

12 December 2020

Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation

1 reference

12 December 2020

CD25+Foxp3+ regulatory T cells facilitate CD4+ T cell clonal anergy induction during the recovery from lymphopenia

1 reference

12 December 2020

Adaptive tolerance of CD4+ T cells in vivo: multiple thresholds in response to a constant level of antigen presentation

1 reference

12 December 2020

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

1 reference

12 December 2020

Antagonistic roles for CTLA-4 and the mammalian target of rapamycin in the regulation of clonal anergy: enhanced cell cycle progression promotes recall antigen responsiveness.

1 reference

12 December 2020

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

12 December 2020

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

1 reference

12 December 2020

Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

1 reference

12 December 2020

Distinct roles for B7-1 (CD-80) and B7-2 (CD-86) in the initiation of experimental allergic encephalomyelitis

1 reference

12 December 2020

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

1 reference

12 December 2020

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

12 December 2020

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

12 December 2020

Control of T cell viability

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12 December 2020

Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation

1 reference

12 December 2020

Self-reactive T cells selected on thymic cortical epithelium are polyclonal and are pathogenic in vivo.

1 reference

12 December 2020

Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4.

1 reference

12 December 2020

Immune cell migration as a means to control immune privilege: lessons from the CNS and tumors

1 reference

12 December 2020

Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin.

1 reference

12 December 2020

Tissue expression of PD-L1 mediates peripheral T cell tolerance.

1 reference

12 December 2020

The molecular signature of CD8+ T cells undergoing deletional tolerance

1 reference

12 December 2020

Toll-dependent control mechanisms of CD4 T cell activation.

1 reference

12 December 2020

Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection

1 reference

12 December 2020

Clonal anergy is maintained independently of T cell proliferation

1 reference

12 December 2020

T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity

1 reference

12 December 2020

Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen

1 reference

12 December 2020

TAM receptors are pleiotropic inhibitors of the innate immune response

1 reference

12 December 2020

Low avidity recognition of self-antigen by T cells permits escape from central tolerance.

1 reference

12 December 2020

CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity

1 reference

12 December 2020

The link between lymphocyte deficiency and autoimmunity: roles of endogenous T and B lymphocytes in tolerance

1 reference

12 December 2020

CTLA-4 control over Foxp3+ regulatory T cell function

1 reference

12 December 2020

Maintenance of peripheral tolerance through controlled tissue homing of antigen-specific T cells in K14-mOVA mice.

1 reference

12 December 2020

Visualizing the generation of memory CD4 T cells in the whole body

1 reference

12 December 2020

Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.

1 reference

12 December 2020

Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells

1 reference

12 December 2020

Selective Rac1 inhibition in dendritic cells diminishes apoptotic cell uptake and cross-presentation in vivo

1 reference

12 December 2020

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

12 December 2020

Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex

1 reference

12 December 2020

Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells

1 reference

12 December 2020

The microanatomy of T-cell responses

1 reference

12 December 2020

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

1 reference

12 December 2020

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

1 reference

12 December 2020

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

1 reference

12 December 2020

Tolerogenic dendritic cells and the quest for transplant tolerance

1 reference

12 December 2020

Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4

1 reference

12 December 2020

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

1 reference

12 December 2020

Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE

1 reference

12 December 2020

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

1 reference

12 December 2020

Egr-2 and Egr-3 are negative regulators of T cell activation.

1 reference

12 December 2020

Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation

1 reference

12 December 2020

Immune tolerance after delivery of dying cells to dendritic cells in situ

1 reference

12 December 2020

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

12 December 2020

Pathway analysis of seven common diseases assessed by genome-wide association

1 reference

12 December 2020

mTOR at the crossroads of T cell proliferation and tolerance

1 reference

12 December 2020

CTLA-4 can function as a negative regulator of T cell activation

1 reference

12 December 2020

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

1 reference

12 December 2020

Transcriptional mechanisms underlying lymphocyte tolerance.

1 reference

12 December 2020

A role for the endoplasmic reticulum protein retrotranslocation machinery during crosspresentation by dendritic cells

1 reference

12 December 2020

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

1 reference

12 December 2020

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

12 December 2020

Cutting edge: contributions of apoptosis and anergy to systemic T cell tolerance

1 reference

12 December 2020

Projection of an immunological self shadow within the thymus by the aire protein

1 reference

12 December 2020

Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.

1 reference

12 December 2020

MerTK is required for apoptotic cell-induced T cell tolerance

1 reference

12 December 2020

Dendritic cells and the control of immunity

1 reference

12 December 2020

Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family

1 reference

12 December 2020

Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction

1 reference

12 December 2020

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

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12 December 2020

Real-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activation

1 reference

12 December 2020

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

1 reference

12 December 2020

Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity

1 reference

12 December 2020

Clonal anergy is induced in vitro by T cell receptor occupancy in the absence of proliferation

1 reference

12 December 2020

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

1 reference

12 December 2020

Preferential localization of effector memory cells in nonlymphoid tissue

1 reference

12 December 2020