(Q37658846)

21 August 2017

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title

Inhibitors of diacylglycerol acyltransferase: a review of 2008 patents (English)

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21 August 2017

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Andrew J King

1

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21 August 2017

Andrew S Judd

series ordinal

2

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21 August 2017

Andrew J Souers

series ordinal

3

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21 August 2017

language of work or name

English

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publication date

1 January 2010

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Expert Opinion on Therapeutic Patents

21 August 2017

published in

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21 August 2017

volume

20

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21 August 2017

issue

1

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21 August 2017

page(s)

19-29

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Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Insulin resistance and steatosis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

The Monoglyceride Pathway of Fat Absorption in Man*

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Discovery of a potent, selective, and orally efficacious pyrimidinooxazinyl bicyclooctaneacetic acid diacylglycerol acyltransferase-1 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Diacylglycerol acyltransferase 1 inhibition lowers serum triglycerides in the Zucker fatty rat and the hyperlipidemic hamster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Development of the mammary gland requires DGAT1 expression in stromal and epithelial tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Lipopenia and skin barrier abnormalities in DGAT2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903499305

10.1517/13543770903499305

21 January 2018

Identifiers

DOI

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21 August 2017

1 reference