(Q37668615)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24683533%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Effects of mutations and deletions in the human optineurin gene (English)

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12 March 2020

3

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12 March 2020

author name string

Sanja Turturro

1

1 reference

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12 March 2020

Xiang Shen

2

1 reference

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12 March 2020

Beatrice Yjt Yue

4

1 reference

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12 March 2020

Hongyu Ying

5

1 reference

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12 March 2020

publication date

19 February 2014

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12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24683533%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

3

1 reference

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12 March 2020

page(s)

99

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https://scigraph.springernature.com/pub.10.1186/2193-1801-3-99

12 March 2020

exact match

0 references

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Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations

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Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

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Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation

23 August 2017

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Impairment of protein trafficking upon overexpression and mutation of optineurin

23 August 2017

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Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone

23 August 2017

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Mutations of optineurin in amyotrophic lateral sclerosis

23 August 2017

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23 August 2017

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Protein conformational pathology in Alzheimer's and other neurodegenerative diseases; new targets for therapy

23 August 2017

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Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection

23 August 2017

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Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene

23 August 2017

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Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth

23 August 2017

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NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.

23 August 2017

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Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus

23 August 2017

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The genetics of primary open-angle glaucoma: a review

23 August 2017

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The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration

23 August 2017

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Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP

23 August 2017

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23 August 2017

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23 August 2017

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Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types

23 August 2017

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Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains

23 August 2017

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23 August 2017

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A forensic path to RGC-5 cell line identification: lessons learned

23 August 2017

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Myosin VI and its cargo adaptors - linking endocytosis and autophagy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

A yeast model of optineurin proteinopathy reveals a unique aggregation pattern associated with cellular toxicity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Optineurin with amyotrophic lateral sclerosis-related mutations abrogates inhibition of interferon regulatory factor-3 activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Primary open-angle glaucoma genes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Recharacterization of the RGC-5 retinal ganglion cell line

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Soluble CD44 is cytotoxic to trabecular meshwork and retinal ganglion cells in vitro.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Optineurin suppression causes neuronal cell death via NF-κB pathway.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967732

The majority of the genetic risk for Paget’s disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F2193-1801-3-99

Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation

21 January 2018

1 reference

12 December 2020

Optineurin: a new vision of cell division control

1 reference

12 December 2020

The cell and molecular biology of complex forms of glaucoma: updates on genetic, environmental, and epigenetic risk factors

1 reference

12 December 2020

Screening of OPTN in French familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene

1 reference

12 December 2020

Optineurin in neurodegenerative diseases

1 reference

12 December 2020

Identifiers

DOI

10.1186/2193-1801-3-99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24683533%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24683533%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24683533%20AND%20SRC:MED&resulttype=core&format=json