(Q37670186)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

review article

1 reference

title

Emerging drugs in sepsis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Marc Leone

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Fabrice Michel

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Sandrine Wiramus

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Claude Martin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

1 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Emerging Drugs

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

41-52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20055688%20AND%20SRC:MED&resulttype=core&format=json

Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008

16 January 2020

cites work

1 reference

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Activated protein C for the treatment of severe sepsis

21 January 2018

1 reference

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The epidemiology of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Effectiveness of treatments for severe sepsis: a prospective, multicenter, observational study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Predictors of 30-day mortality and hospital costs in patients with ventilator-associated pneumonia attributed to potentially antibiotic-resistant gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

How to break the vicious circle of antibiotic resistances?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

New developments in carbapenems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Efficacy and safety of intravenous infusion of doripenem versus imipenem in ventilator-associated pneumonia: a multicenter, randomized study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Update on the treatment of Pseudomonas aeruginosa pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Comparative review of the carbapenems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Ventilator-associated pneumonia: breaking the vicious circle of antibiotic overuse.

21 January 2018

1 reference

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Efficacy and safety of linezolid compared with vancomycin in a randomized, double-blind study of febrile neutropenic patients with cancer

21 January 2018

1 reference

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Complicated skin and skin-structure infections and catheter-related bloodstream infections: noninferiority of linezolid in a phase 3 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Cost-effectiveness of linezolid vs vancomycin in suspected methicillin-resistant Staphylococcus aureus nosocomial pneumonia in Germany

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Cost-effectiveness of linezolid versus vancomycin for hospitalised patients with complicated skin and soft-tissue infections in Germany

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Cost-effectiveness analysis of linezolid vs. vancomycin in treating methicillin-resistant Staphylococcus aureus complicated skin and soft tissue infections using a decision analytic model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Ceftobiprole: a new broad spectrum cephalosporin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Activities of ceftobiprole, linezolid, vancomycin, and daptomycin against community-associated and hospital-associated methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Ceftaroline: a novel broad-spectrum cephalosporin with activity against meticillin-resistant Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Phase 2 study of ceftaroline versus standard therapy in treatment of complicated skin and skin structure infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Activity of the new cephalosporin ceftaroline against bacteraemia isolates from patients with community-acquired pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Colistin serum concentrations after intravenous administration in critically ill patients with serious multidrug-resistant, gram-negative bacilli infections: a prospective, open-label, uncontrolled study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Population pharmacokinetic analysis of colistin methanesulfonate and colistin after intravenous administration in critically ill patients with infections caused by gram-negative bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Inhaled colistin as monotherapy for multidrug-resistant gram (-) nosocomial pneumonia: a case series

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Animal models of sepsis: why does preclinical efficacy fail to translate to the clinical setting?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Early goal-directed therapy in severe sepsis and septic shock: a contemporary review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Plasticity of the systemic inflammatory response to acute infection during critical illness: development of the riboleukogram

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Experimental models of sepsis and their clinical relevance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Importance of hemostatic gene polymorphisms for susceptibility to and outcome of severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Randomized, double-blind, placebo-controlled trial of granulocyte colony-stimulating factor in patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Hydrocortisone therapy for patients with septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Efficacy and safety of recombinant human activated protein C for severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death

21 January 2018

1 reference

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Extended evaluation of recombinant human activated protein C United States Trial (ENHANCE US): a single-arm, phase 3B, multicenter study of drotrecogin alfa (activated) in severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Beneficial effects of recombinant human activated protein C in a ewe model of septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Rapid and beneficial hemodynamic effects of activated protein C in septic shock patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

EF6265, a novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor, protects against sepsis-induced organ dysfunction in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Enoxaparin attenuates endothelial damage with less bleeding compared with unfractionated heparin in endotoxemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Statins for sepsis: a critical and updated review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Statins for the prevention and treatment of infections: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Preadmission use of statins and outcomes after hospitalization with pneumonia: population-based cohort study of 29,900 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Statin therapy is associated with decreased mortality in patients with infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Reduction in mortality associated with statin therapy in patients with severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: a randomized double-blind placebo controlled clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Aspiration pneumonia and dysphagia in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Reduction of risk of pneumonia associated with use of angiotensin I converting enzyme inhibitors in elderly inpatients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Effects of an angiotensin-converting enzyme inhibitor on the inflammatory response in in vivo and in vitro models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Use of ACE inhibitors and risk of community-acquired pneumonia: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Involvement of central angiotensin II type 1 receptors in LPS-induced systemic vasopressin release and blood pressure regulation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Role of the renin-angiotensin system in ventilator-induced lung injury: an in vivo study in a rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Losartan prevents sepsis-induced acute lung injury and decreases activation of nuclear factor kappaB and mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

The catecholamine cytokine balance: interaction between the brain and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Beta-adrenergic blockade exacerbates sepsis-induced changes in tumor necrosis factor alpha and interleukin-6 in skeletal muscle and is associated with impaired translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

beta2 Adrenoreceptor blockade attenuates the hyperinflammatory response induced by traumatic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Combined milrinone and enteral metoprolol therapy in patients with septic myocardial depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Reversing established sepsis with antagonists of endogenous high-mobility group box 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

A1 adenosine receptor knockout mice exhibit increased mortality, renal dysfunction, and hepatic injury in murine septic peritonitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Cellular dysfunction in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis--there is nothing more practical than a good theory

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Mitochondria, endoplasmic reticulum, and alternative pathways of cell death in critical illness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

MitoQ administration prevents endotoxin-induced cardiac dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Poly(ADP-ribose) polymerase: a new therapeutic target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Antioxidant therapy in critically septic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Critically elucidating the role of selenium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Host-pathogen interactions in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

The pathophysiology and treatment of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Dysregulation of in vitro cytokine production by monocytes during sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Herpes simplex virus lung infection in patients undergoing prolonged mechanical ventilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Cytomegalovirus reactivation in critically ill immunocompetent patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860

Non-antibiotic treatment for bacterial infections: how to validate chance findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728210903559860