(Q37676684)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20080466%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

review article

1 reference

title

Molecular basis for the treatment of renal cell carcinoma (English)

1 reference

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16 January 2020

6

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16 January 2020

author name string

Cristina Suárez

1

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16 January 2020

Rafael Morales

2

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16 January 2020

Eva Muñoz

3

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16 January 2020

Jordi Rodón

4

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16 January 2020

Claudia M Valverde

5

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16 January 2020

publication date

1 January 2010

1 reference

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Clinical and Translational Oncology

16 January 2020

published in

1 reference

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16 January 2020

volume

12

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16 January 2020

issue

1

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16 January 2020

page(s)

15-21

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https://scigraph.springernature.com/pub.10.1007/s12094-010-0461-4

16 January 2020

exact match

0 references

cites work

Overproduction of vascular endothelial growth factor related to von Hippel-Lindau tumor suppressor gene mutations and hypoxia-inducible factor-1 alpha expression in renal cell carcinomas.

1 reference

12 December 2020

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

1 reference

12 December 2020

A phase II, open-label study of gefitinib (IRESSA) in patients with locally advanced, metastatic, or relapsed renal-cell carcinoma.

1 reference

12 December 2020

von Hippel-Lindau disease

1 reference

12 December 2020

Two North American families with hereditary papillary renal carcinoma and identical novel mutations in the MET proto-oncogene

1 reference

12 December 2020

Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

1 reference

12 December 2020

Molecular basis of the VHL hereditary cancer syndrome

1 reference

12 December 2020

Markedly increased amounts of messenger RNAs for vascular endothelial growth factor and placenta growth factor in renal cell carcinoma associated with angiogenesis

1 reference

12 December 2020

Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

1 reference

12 December 2020

Randomized phase II study of erlotinib combined with bevacizumab compared with bevacizumab alone in metastatic renal cell cancer

1 reference

12 December 2020

Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

1 reference

12 December 2020

Hereditary Multiple Fibrofolliculomas With Trichodiscomas and Acrochordons

1 reference

12 December 2020

Membrane-anchored growth factors, the epidermal growth factor family: beyond receptor ligands

1 reference

12 December 2020

Sorafenib in advanced clear-cell renal-cell carcinoma

1 reference

12 December 2020

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

1 reference

12 December 2020

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

1 reference

12 December 2020

VHL alterations in human clear cell renal cell carcinoma: association with advanced tumor stage and a novel hot spot mutation

1 reference

12 December 2020

Novel mutations of the MET proto-oncogene in papillary renal carcinomas.

1 reference

12 December 2020

Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome

1 reference

12 December 2020

Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study

1 reference

12 December 2020

The expression of epidermal growth factor receptor and transforming growth factor alpha in renal cell carcinoma

1 reference

12 December 2020

Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome

1 reference

12 December 2020

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

1 reference

12 December 2020

Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas

1 reference

12 December 2020

Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma

1 reference

12 December 2020

Molecular cytogenetics of renal cell tumors

1 reference

12 December 2020

Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

1 reference

12 December 2020

VEGF/VEGFR signalling as a target for inhibiting angiogenesis

1 reference

12 December 2020

Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells

1 reference

12 December 2020

Characterization of membranous and cytoplasmic EGFR expression in human normal renal cortex and renal cell carcinoma

1 reference

12 December 2020

The genetic basis of cancer of the kidney

1 reference

12 December 2020

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis

1 reference

12 December 2020

Von Hippel-Lindau Disease

1 reference

12 December 2020

Hypoxia inducible factor activates the transforming growth factor-alpha/epidermal growth factor receptor growth stimulatory pathway in VHL(-/-) renal cell carcinoma cells

1 reference

12 December 2020

Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America

1 reference

12 December 2020

Hereditary papillary renal cell carcinoma

1 reference

12 December 2020

Vascular endothelial growth factor expression is increased in renal cell carcinoma

1 reference

12 December 2020

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

1 reference

12 December 2020

Vascular endothelial growth factor overexpression is correlated with von Hippel-Lindau tumor suppressor gene inactivation in patients with sporadic renal cell carcinoma

1 reference

12 December 2020

Identification of the von Hippel-Lindau disease tumor suppressor gene

1 reference

12 December 2020

Genetics of human cancer

1 reference

12 December 2020

Hypoxia--a key regulatory factor in tumour growth

1 reference

12 December 2020

VHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma

1 reference

12 December 2020

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

1 reference

12 December 2020

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

1 reference

12 December 2020

Invasive growth: a MET-driven genetic programme for cancer and stem cells

1 reference

12 December 2020

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

1 reference

12 December 2020

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

1 reference

12 December 2020

Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer

1 reference

12 December 2020

Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial.

1 reference

12 December 2020

Phase II trial of antiepidermal growth factor receptor antibody C225 in patients with advanced renal cell carcinoma.

1 reference

12 December 2020

Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial

1 reference

12 December 2020

Phase I trial of the oral antiangiogenesis agent AG-013736 in patients with advanced solid tumors: pharmacokinetic and clinical results

1 reference

12 December 2020

Tumour suppression by the human von Hippel-Lindau gene product

1 reference

12 December 2020

Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

1 reference

12 December 2020

Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206

1 reference

12 December 2020

Growing roles for the mTOR pathway

1 reference

12 December 2020

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

1 reference

12 December 2020

Hereditary leiomyomatosis and renal cell cancer (HLRCC).

1 reference

12 December 2020

High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors.

1 reference

12 December 2020

Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis

1 reference

12 December 2020

Renal Tumors in the Birt-Hogg-Dubé Syndrome

1 reference

12 December 2020

Pazopanib: a novel multitargeted tyrosine kinase inhibitor

1 reference

12 December 2020

Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas.

1 reference

12 December 2020

Mouse-human chimeric anti-epidermal growth factor receptor antibody C225 inhibits the growth of human renal cell carcinoma xenografts in nude mice

1 reference

12 December 2020

Molecular design and clinical development of VEGFR kinase inhibitors

1 reference

12 December 2020

Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer

1 reference

12 December 2020

In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.

1 reference

12 December 2020

Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma

1 reference

12 December 2020

Role of VHL gene mutation in human cancer

1 reference

12 December 2020

10.1007/S12094-010-0461-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20080466%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference