(Q37679991)

21 August 2017

1 reference

title

Transgenic animals modelling polyamine metabolism-related diseases (English)

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21 August 2017

Leena Alhonen

1

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21 August 2017

Anne Uimari

2

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21 August 2017

Marko Pietilä

3

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21 August 2017

Mervi T Hyvönen

4

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21 August 2017

Eija Pirinen

5

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21 August 2017

Tuomo A Keinänen

6

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21 August 2017

publication date

4 November 2009

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21 August 2017

published in

Essays in Biochemistry

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21 August 2017

volume

46

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21 August 2017

page(s)

125-144

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Activation of polyamine catabolism profoundly alters tissue polyamine pools and affects hair growth and female fertility in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Characterization of transgenic mice with widespread overexpression of spermine synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Animal disease models generated by genetic engineering of polyamine metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Elevated seizure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Overexpression of spermidine/spermine N1-acetyltransferase elevates the threshold to pentylenetetrazol-induced seizure activity in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Neuroprotective role of ornithine decarboxylase activation in transient focal cerebral ischaemia: a study using ornithine decarboxylase-overexpressing transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Spermidine/spermine N1-acetyltransferase overexpression in mice induces hypoactivity and spatial learning impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Spermidine/spermine-N1-acetyltransferase ablation protects against liver and kidney ischemia-reperfusion injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Suprabasal induction of ornithine decarboxylase in adult mouse skin is sufficient to activate keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Disturbed keratinocyte differentiation in transgenic mice and organotypic keratinocyte cultures as a result of spermidine/spermine N-acetyltransferase overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Activation of polyamine catabolism in transgenic rats induces acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

activated polyamine catabolism in acute pancreatitis: alpha-methylated polyamine analogues prevent trypsinogen activation and pancreatitis-associated mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

A polyamine analog bismethylspermine ameliorates severe pancreatitis induced by intraductal infusion of taurodeoxycholate

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N(1)-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Altered levels of growth-related and novel gene transcripts in reproductive and other tissues of female mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Transgenic mice over-expressing the human spermidine synthase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Polyamines are required for the initiation of rat liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Acute pancreatitis induced by activation of the polyamine catabolism in gene-modified mice and rats overexpressing spermidine/spermine N1-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Haploinsufficiency for odc modifies mouse skin tumor susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

The ornithine decarboxylase gene is essential for cell survival during early murine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBSE0460009

21 January 2018

Identifiers

DOI

10.1042/BSE0460009

1 reference

21 August 2017

1 reference