(Q37683331)

English

Fatty acid chain elongation in palmitate-perfused working rat heart: mitochondrial acetyl-CoA is the source of two-carbon units for chain elongation

scientific article published on 20 February 2014

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Fatty acid chain elongation in palmitate-perfused working rat heart: mitochondrial acetyl-CoA is the source of two-carbon units for chain elongation (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

0 references

1 reference

based on heuristic

inferred from title

author name string

Janos Kerner

1

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Paul E Minkler

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Edward J Lesnefsky

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Charles L Hoppel

4

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

language of work or name

0 references

publication date

20 February 2014

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

289

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

14

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

10223-10234

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Insulin resistance: metabolic mechanisms and consequences in the heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

The continuing evolution of the Langendorff and ejecting murine heart: new advances in cardiac phenotyping.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Succinyl-CoA ligase deficiency: a mitochondrial hepatoencephalomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Elovl6: a new player in fatty acid metabolism and insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Fatty acid chain-elongation in perfused rat heart: synthesis of stearoylcarnitine from perfused palmitate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Fatty acid elongases in mammals: their regulation and roles in metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Elongation of long-chain fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Cloning, expression, characterization, and interaction of two components of a human mitochondrial fatty acid synthase. Malonyltransferase and acyl carrier protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

The subcellular localization of acetyl-CoA carboxylase 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

The fatty acid chain elongation system of mammalian endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 August 2017

Stearoyl-CoA desaturase: rogue or innocent bystander?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

6 September 2017

Very long-chain fatty acids: elongation, physiology and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

6 September 2017

Novel qualitative aspects of tissue fatty acids related to metabolic regulation: lessons from Elovl6 knockout

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

6 September 2017

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

6 September 2017

Malonyl-CoA metabolism in cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

6 September 2017

Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

14 September 2017

Mechanisms and physiological roles of fatty acid chain elongation in microsomes and mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

14 September 2017

Nicotinamide adenine dinucleotide phosphate-converting enzymes and adenosine triphosphate citrate lyase in some tissues and organs of New Zealand obese mice with special reference to the enzyme pattern of the pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

14 September 2017

Carnitine and derivatives in rat tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 June 2018

Reversible sensitization and desensitization of carnitine palmitoyltransferase I to inhibition by malonyl-CoA in isolated rat liver mitochondria. Significance for the mechanism of malonyl-CoA-induced sensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 June 2018

Purification and some kinetic properties of rat liver ATP citrate lyase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 June 2018

Characterization of the fatty acid elongation system in soluble extracts and membrane preparations of rat liver mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 June 2018

Palmityl-CoA and palmitylcarnitine interactions in mitochondrial fatty acid elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 June 2018

Hysteretic behaviour of carnitine palmitoyltransferase. The effect of preincubation with malonyl-CoA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 June 2018

Identification of ATP citrate lyase as a phosphoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

23 June 2018

The novel mutation p.Asp251Asn in the β-subunit of succinate-CoA ligase causes encephalomyopathy and elevated succinylcarnitine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Mass spectrometric demonstration of the presence of liver carnitine palmitoyltransferase-I (CPT-I) in heart mitochondria of adult rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Quantification of carnitine and acylcarnitines in biological matrices by HPLC electrospray ionization-mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

An algorithm for the deconvolution of mass spectroscopic patterns in isotope labeling studies. Evaluation for the hydrogen-deuterium exchange reaction in ketones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Peroxisomal fatty acid oxidation is a substantial source of the acetyl moiety of malonyl-CoA in rat heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Infantile mitochondrial DNA depletion syndrome associated with methylmalonic aciduria and 3‐methylcrotonyl‐CoA and propionyl‐CoA carboxylase deficiencies in two unrelated patients: A new phenotype of mtDNA depletion syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Probing the link between citrate and malonyl-CoA in perfused rat hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Rates of mitochondrial and peroxisomal beta-oxidation of palmitate change during postnatal development and food deprivation in liver, kidney and heart of pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Differential fatty acid accretion in heart, liver and adipose tissues of rats fed beef tallow, fish oil, olive oil and safflower oils at three levels of energy intake.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Interaction of malonyl-CoA and related compounds with mitochondria from different rat tissues. Relationship between ligand binding and inhibition of carnitine palmitoyltransferase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974991

1 September 2018

Linoleic Acid Metabolism in Primary Cultures of Adult Rat Cardiomyocytes Is Impaired by Aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5'-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The malonyl-CoA-sensitive form of carnitine palmitoyltransferase is not localized exclusively in the outer membrane of rat liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of chronic ethanol consumption on fatty acid profile of heart tissue in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisomal fatty acid oxidation in rat and human tissues. Effect of nutritional state, clofibrate treatment and postnatal development in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carnitine acetyltransferase is not a cytosolic enzyme in rat heart and therefore cannot function in the energy-linked regulation of cardiac fatty acid oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of unsaturated acylcarnitine molecular species during acute myocardial ischemia: metabolic compartmentalization of products of fatty acyl chain elongation in the acylcarnitine pool

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous quantification of acylcarnitine isomers containing dicarboxylic acylcarnitines in human serum and urine by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of long-chain polyunsaturated fatty acids in isolated cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of long chain fatty acid activation in heart muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of pH and acyl-CoA chain length on the conversion of heart mitochondrial CPT-I/CPTo to a high affinity, malonyl-CoA-inhibited state

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of malonyl-coenzyme A in tissue specimens by high-performance liquid chromatography/mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Fatty Acid Utilization in Isolated Perfused Rat Hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24558043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.524314

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37683331&oldid=2167138427"