(Q37684574)

22 August 2017

Genetic regulatory network motifs constrain adaptation through curvature in the landscape of mutational (co)variance (English)

1 reference

22 August 2017

Tyler D Hether

1

1 reference

PMC publication ID

3975670

22 August 2017

Paul A Hohenlohe

series ordinal

2

1 reference

22 August 2017

4 December 2013

1 reference

22 August 2017

15

1 reference

inferred from page(s)

published in

Evolution

1 reference

22 August 2017

68

1 reference

22 August 2017

4

1 reference

22 August 2017

950-964

1 reference

The effects of stochastic and episodic movement of the optimum on the evolution of the G-matrix and the response of the trait mean to selection.

22 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Parameters in dynamic models of complex traits are containers of missing heritability.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Negative feedback confers mutational robustness in yeast transcription factor regulation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Hierarchical cluster-based partial least squares regression (HC-PLSR) is an efficient tool for metamodelling of nonlinear dynamic models

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Dissecting genetic networks underlying complex phenotypes: the theoretical framework

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Phenomics: the next challenge

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Hundreds of variants clustered in genomic loci and biological pathways affect human height

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Common SNPs explain a large proportion of the heritability for human height

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

The genetic landscape of a cell

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Genotype-phenotype mapping and the end of the 'genes as blueprint' metaphor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Adaptation by introgression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Systematic mapping of genetic interaction networks

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Shadows of complexity: what biological networks reveal about epistasis and pleiotropy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Understanding quantitative genetics in the systems biology era.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Understanding the evolution and stability of the G-matrix

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Patterns of quantitative genetic variation in multiple dimensions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

From classical genetics to quantitative genetics to systems biology: modeling epistasis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

EVOLUTION IN MENDELIAN POPULATIONS

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Statistical epistasis is a generic feature of gene regulatory networks

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Uncovering cryptic genetic variation.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Estimating genetic parameters in natural populations using the "animal model"

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

A gene-coexpression network for global discovery of conserved genetic modules

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

The adaptive landscape as a conceptual bridge between micro- and macroevolution

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Variation, selection and evolution of function-valued traits

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Gene regulatory networks generating the phenomena of additivity, dominance and epistasis.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

On the origin of species by sympatric speciation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Comparing mutational variabilities.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

A stochastic model concerning the maintenance of genetic variability in quantitative characters

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Hybridization and speciation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Evolution in developmental phenotype space

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Evolutionary systems biology: historical and philosophical perspectives on an emerging synthesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Stability of the G-matrix in a population experiencing pleiotropic mutation, stabilizing selection, and genetic drift

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

A general mechanism for network-dosage compensation in gene circuits

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Systematic discovery of functional modules and context-specific functional annotation of human genome

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Properties of spontaneous mutational variance and covariance for wing size and shape in Drosophila melanogaster

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Rapid and unpredictable changes of the G-matrix in a natural bird population over 25 years

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Phenotypic plasticity facilitates mutational variance, genetic variance, and evolvability along the major axis of environmental variation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

An ecologist's guide to the animal model

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

How much do genetic covariances alter the rate of adaptation?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Measuring and comparing evolvability and constraint in multivariate characters.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

From genotype to phenotype: systems biology meets natural variation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

The evolution of genetic networks by non-adaptive processes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Evolution and stability of the G-matrix on a landscape with a moving optimum.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

How should we explain variation in the genetic variance of traits?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975670

Riemannian Geometry and Geometric Analysis

1 September 2018

1 reference

THE MEASUREMENT OF SELECTION ON CORRELATED CHARACTERS.

21 January 2018

1 reference

Parameter expansion to accelerate EM: the PX-EM algorithm

21 January 2018

1 reference

Perspective: Complex Adaptations and the Evolution of Evolvability

21 January 2018

1 reference

Population Dependent Fourier Decomposition of Fitness Landscapes over Recombination Spaces: Evolvability of Complex Characters

21 January 2018

1 reference

EFFECTS OF MIGRATION ON THE GENETIC COVARIANCE MATRIX

21 January 2018

1 reference

Comparative quantitative genetics: evolution of the G matrix

21 January 2018

1 reference

THE MUTATION MATRIX AND THE EVOLUTION OF EVOLVABILITY

21 January 2018

1 reference

12 December 2020

Effects of epistasis and the evolution of genetic architecture: exact results for a 2-locus model

1 reference

12 December 2020

THE MEASUREMENT OF SELECTION ON CORRELATED CHARACTERS

1 reference

12 December 2020

PERSPECTIVE: COMPLEX ADAPTATIONS AND THE EVOLUTION OF EVOLVABILITY.

1 reference

12 December 2020

ADAPTIVE RADIATION ALONG GENETIC LINES OF LEAST RESISTANCE.

1 reference

12 December 2020

QUANTITATIVE GENETIC ANALYSIS OF MULTIVARIATE EVOLUTION, APPLIED TO BRAIN:BODY SIZE ALLOMETRY.

1 reference

12 December 2020

Identifiers

DOI

10.1111/EVO.12313

1 reference

22 August 2017

1 reference

PMC publication ID

3975670

22 August 2017

PubMed publication ID

24219635

1 reference

PMC publication ID

3975670