(Q37688945)

22 August 2017

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title

Genetically modified mice-successes and failures of a widely used technology (English)

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22 August 2017

Hayo Castrop

1

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22 August 2017

publication date

6 February 2010

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22 August 2017

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22 August 2017

volume

459

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22 August 2017

issue

4

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22 August 2017

page(s)

557-567

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High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors

22 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00424-009-0770-Z

Enhanced release of prostaglandins contributes to flow-induced arteriolar dilation in eNOS knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0770-Z

Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0770-Z

Functional expression of the cre-lox site-specific recombination system in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-009-0770-Z

The pharmacology and clinical uses of tamoxifen

21 January 2018

1 reference

12 December 2020

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

1 reference

12 December 2020

The Flp recombinase of the 2-microns plasmid of Saccharomyces cerevisiae.

1 reference

12 December 2020

Activation of the interferon system by short-interfering RNAs

1 reference

12 December 2020

Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.

1 reference

12 December 2020

DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages

1 reference

12 December 2020

Towards an integrated view of Wnt signaling in development

1 reference

12 December 2020

1 reference

12 December 2020

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

1 reference

12 December 2020

Elevated blood pressures in mice lacking endothelial nitric oxide synthase.

1 reference

12 December 2020

Mouse development and cell proliferation in the absence of D-cyclins.

1 reference

12 December 2020

Ligand-activated site-specific recombination in mice

1 reference

12 December 2020

Direct removal in the mouse of a floxed neo gene from a three-loxP conditional knockout allele by two novel approaches

1 reference

12 December 2020

EDHF mediates flow-induced dilation in skeletal muscle arterioles of female eNOS-KO mice

1 reference

12 December 2020

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse

1 reference

12 December 2020

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

12 December 2020

High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells.

1 reference

12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

12 December 2020

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

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12 December 2020

Review of the toxicology of tamoxifen

1 reference

12 December 2020

Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression

1 reference

12 December 2020

Tissue-specific transgenic, conditional knockout and knock-in mice of genes in the canonical Wnt signaling pathway

1 reference

12 December 2020

The knockout mouse project

1 reference

12 December 2020

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

1 reference

12 December 2020

Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors

1 reference

12 December 2020

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

1 reference

12 December 2020

Reporter gene recombination in juxtaglomerular granular and collecting duct cells by human renin promoter-Cre recombinase transgene.

1 reference

12 December 2020

Macula densa control of renin secretion and preglomerular resistance in mice with selective deletion of the B isoform of the Na,K,2Cl co-transporter

1 reference

12 December 2020

A public gene trap resource for mouse functional genomics

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12 December 2020

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

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12 December 2020

Site-specific insertion of DNA into a pseudorabies virus vector

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12 December 2020

Arachidonic acid metabolism

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12 December 2020

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

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12 December 2020

Brief expression of a GFP cre fusion gene in embryonic stem cells allows rapid retrieval of site-specific genomic deletions

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12 December 2020

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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12 December 2020

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

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12 December 2020

Multiplex Cre/lox recombination permits selective site-specific DNA targeting to both a natural and an engineered site in the yeast genome

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12 December 2020

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

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12 December 2020

Regulation and mechanisms of mammalian double-strand break repair

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12 December 2020

Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened

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12 December 2020

Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells

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12 December 2020

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

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12 December 2020

Small interfering RNA and gene silencing in transgenic mice and rats

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12 December 2020

The mechanism of naked DNA uptake and expression

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12 December 2020

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

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12 December 2020

Gene structure prediction and alternative splicing analysis using genomically aligned ESTs

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12 December 2020

Mutant mice and neuroscience: recommendations concerning genetic background. Banbury Conference on genetic background in mice

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12 December 2020

Influence of genetic background and gender on hypertension and renal failure in COX-2-deficient mice

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12 December 2020

In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family

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12 December 2020

Comparative toxicity of oxytetracycline and its semisynthetic derivatives, methacycline and doxycycline

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12 December 2020

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

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12 December 2020

RNA interference: the molecular immune system

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12 December 2020

Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice

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12 December 2020

Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect.

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12 December 2020

Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells

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12 December 2020

Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

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12 December 2020

Abrogation of protein uptake through megalin-deficient proximal tubules does not safeguard against tubulointerstitial injury

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12 December 2020

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference

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12 December 2020

Embryonic origin and lineage of juxtaglomerular cells

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12 December 2020

Knockout rats via embryo microinjection of zinc-finger nucleases

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12 December 2020

Inducible suppression of Fgfr2 and Survivin in ES cells using a combination of the RNA interference (RNAi) and the Cre-LoxP system.

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12 December 2020

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

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12 December 2020

Renal function in mice with targeted disruption of the A isoform of the Na-K-2Cl co-transporter.

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12 December 2020

A detailed study of the substrate specificity of a chimeric restriction enzyme.

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12 December 2020

An enhanced U6 promoter for synthesis of short hairpin RNA.

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12 December 2020

RNA interference in adult mice.

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12 December 2020

Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice

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12 December 2020

Inducible gene targeting in mice using the Cre/lox system

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12 December 2020

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

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12 December 2020

A story of mice and men.

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12 December 2020

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

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12 December 2020

Genetic transformation of mouse embryos by microinjection of purified DNA

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12 December 2020

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

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12 December 2020

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

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12 December 2020

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

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12 December 2020

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

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12 December 2020

Targeted manipulation of mammalian genomes using designed zinc finger nucleases

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12 December 2020

Inhibition of hepatitis B virus in mice by RNA interference

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12 December 2020

Molecular mechanisms of RNAi: implications for development and disease.

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12 December 2020

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

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12 December 2020

Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites

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12 December 2020

RNA interference is mediated by 21- and 22-nucleotide RNAs

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12 December 2020

10.1007/S00424-009-0770-Z

Identifiers

DOI

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22 August 2017

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