(Q37689880)

English

The Soluble Epoxide Hydrolase Inhibitor AR9281 Decreases Blood Pressure, Ameliorates Renal Injury and Improves Vascular Function in Hypertension

scientific article published on 18 December 2009

In more languages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

The Soluble Epoxide Hydrolase Inhibitor AR9281 Decreases Blood Pressure, Ameliorates Renal Injury and Improves Vascular Function in Hypertension (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Soluble epoxide hydrolase

0 references

author name string

John D Imig

1

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Margaret A Carpenter

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Sean Shaw

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

publication date

18 December 2009

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Pharmaceuticals

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

217-227

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

copyright license

Creative Commons Attribution 4.0 International

18 December 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Soluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Soluble epoxide hydrolase, a target with multiple opportunities for cardiovascular drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Regulation of T-cell function by endogenously produced angiotensin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Arachidonic acid cytochrome P450 epoxygenase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Cardiovascular therapeutic aspects of soluble epoxide hydrolase inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Soluble epoxide hydrolase is a therapeutic target for acute inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Epoxide hydrolases: their roles and interactions with lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Nitric oxide, angiotensin II, and reactive oxygen species in hypertension and atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Traditional and emerging cardiovascular risk factors in end-stage renal disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Immunosuppressive treatment protects against angiotensin II-induced renal damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Renin-angiotensin system and renal damage: emerging data on angiotensin II as a proinflammatory mediator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 August 2017

Discovery of spirocyclic secondary amine-derived tertiary ureas as highly potent, selective and bioavailable soluble epoxide hydrolase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

14 September 2017

Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

23 June 2018

Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension

1 reference

https://api.crossref.org/works/10.3390%2FPH2030217

21 January 2018

Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats.

1 reference

https://api.crossref.org/works/10.3390%2FPH2030217

21 January 2018

Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

1 reference

https://api.crossref.org/works/10.3390%2FPH2030217

21 January 2018

Interaction between P450 eicosanoids and nitric oxide in the control of arterial tone in mice

1 reference

https://api.crossref.org/works/10.3390%2FPH2030217

21 January 2018

Role of pressure in angiotensin II-induced renal injury: chronic servo-control of renal perfusion pressure in rats.

1 reference

https://api.crossref.org/works/10.3390%2FPH2030217

21 January 2018

Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-gamma

1 reference

https://api.crossref.org/works/10.3390%2FPH2030217

21 January 2018

Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3978544

1 September 2018

Renin-angiotensin system blockade improves endothelial dysfunction in hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/27713235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II, interstitial inflammation, and the pathogenesis of salt-sensitive hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/27713235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/27713235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/PH2030217

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

ResearchGate publication ID

0 references

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