(Q37691064)

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A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 trans-signaling in a murine model

scientific article published on January 2013

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scholarly article

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Europe PubMed Central

22 August 2017

A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 trans-signaling in a murine model (English)

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Europe PubMed Central

22 August 2017

1 reference

based on heuristic

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based on heuristic

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5

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13 June 2020

author name string

Keunhee Oh

1

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13 June 2020

Ok-Young Lee

2

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13 June 2020

Suh Youn Shon

3

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13 June 2020

Onyou Nam

4

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13 June 2020

Myung Won Seo

6

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13 June 2020

Dong-Sup Lee

7

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13 June 2020

publication date

1 January 2013

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22 August 2017

Breast Cancer Research

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13 June 2020

15

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13 June 2020

5

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13 June 2020

R79

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13 June 2020

describes a project that uses

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11 June 2022

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based on heuristic

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https://scigraph.springernature.com/pub.10.1186/bcr3473

0 references

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979084

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S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites.

1 reference

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1 reference

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Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment

1 reference

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23 August 2017

Transglutaminase 2 facilitates the distant hematogenous metastasis of breast cancer by modulating interleukin-6 in cancer cells

1 reference

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23 August 2017

Breast cancer stem cells, cytokine networks, and the tumor microenvironment

1 reference

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23 August 2017

Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice

1 reference

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23 August 2017

Leukocyte ADAM17 regulates acute pulmonary inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979084

23 August 2017

Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks

1 reference

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23 August 2017

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

1 reference

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23 August 2017

Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung

1 reference

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Mechanism of T cell tolerance induced by myeloid-derived suppressor cells.

1 reference

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23 August 2017

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

1 reference

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23 August 2017

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

1 reference

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23 August 2017

Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model

1 reference

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23 August 2017

The liver is a site for tumor-induced myeloid-derived suppressor cell accumulation and immunosuppression

1 reference

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23 August 2017

Myeloid-derived suppressor cells as regulators of the immune system

1 reference

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23 August 2017

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

1 reference

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23 August 2017

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

1 reference

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23 August 2017

Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.

1 reference

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23 August 2017

Cutting edge: soluble IL-6R is produced by IL-6R ectodomain shedding in activated CD4 T cells

1 reference

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23 August 2017

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

1 reference

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23 August 2017

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

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23 August 2017

Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979084

23 August 2017

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

1 reference

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23 August 2017

Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

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23 August 2017

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

1 reference

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23 August 2017

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

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23 August 2017

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

1 reference

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23 August 2017

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

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Clinical validity/utility, change in practice patterns, and economic implications of risk stratifiers to predict outcomes for early-stage breast cancer: a systematic review

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6 September 2017

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6 September 2017

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IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer

1 reference

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Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells

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14 September 2017

ADAM17-mediated shedding of the IL6R induces cleavage of the membrane stub by gamma-secretase

1 reference

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14 September 2017

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1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24021059

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/BCR3473

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24021059%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Dimensions Publication ID

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24021059%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24021059%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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