(Q37693152)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

review article

1 reference

title

Toxicity of the antimalarial artemisinin and its dervatives (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Bernd Kaina

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

1 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

Critical Reviews in Toxicology

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

405-421

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

Artesunate combinations for treatment of malaria: meta-analysis

18 January 2020

cites work

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Malaria parasites can develop stable resistance to artemisinin but lack mutations in candidate genes atp6 (encoding the sarcoplasmic and endoplasmic reticulum Ca2+ ATPase), tctp, mdr1, and cg10.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

The oral route for the administration of cytotoxic drugs: strategies to increase the efficiency and consistency of drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artesunate. A review of its pharmacology and therapeutic efficacy in the treatment of malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Electrocardiographic monitoring in severe falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Toxicity of artemisinin [Artemisia annua L.] in two different periods of pregnancy in Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Monitoring and evaluation of malaria in pregnancy - developing a rational basis for control

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Plasmodicidal effect of desferrioxamine B in human vivax or falciparum malaria from Thailand

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Topical application of artesunate on guinea pig allergic contact dermatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Embryotoxicity of the artemisinin antimalarials and potential consequences for use in women in the first trimester

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artesunate: developmental toxicity and toxicokinetics in monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Clinical pharmacology and therapeutic potential of artemisinin and its derivatives in the treatment of malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

The safety of artemisinins during pregnancy: a pressing question

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artemisinin combination therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artemisinins target the SERCA of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Willmar Schwabe Award 2006: antiplasmodial and antitumor activity of artemisinin--from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Activity of drugs from traditional Chinese medicine toward sensitive and MDR1- or MRP1-overexpressing multidrug-resistant human CCRF-CEM leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Molecular modes of action of artesunate in tumor cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Some pregnancy-related effects of artemether in laboratory animals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Evaluation of the developmental toxicity of artemether during different phases of rat pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Haemoglobinuria in a 38-year-old French expatriate man living in Cameroon following artemisinin-based antimalarial treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Neurotoxicity due to antimalarial therapy associated with misdiagnosis of malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Behavioral and neural toxicity of arteether in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Behavioral and neural toxicity of the artemisinin antimalarial, arteether, but not artesunate and artelinate, in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Effects of arteether on an auditory radial-arm maze task in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Antimalarial drugs modulate the expression of monocyte receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artemisinin derivatives: toxic for laboratory animals, safe for humans?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

A controlled trial of artemether or quinine in Vietnamese adults with severe falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Arteether administration in humans: preliminary studies of pharmacokinetics, safety and tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

The role of downstream signaling pathways of the epidermal growth factor receptor for Artesunate's activity in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artemisinins: mechanisms of action and potential for resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Severe allergic reactions to oral artesunate: a report of two cases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Yeast model uncovers dual roles of mitochondria in action of artemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Dihydroarteannuin ameliorates lupus symptom of BXSB mice by inhibiting production of TNF-alpha and blocking the signaling pathway NF-kappa B translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Toxicity evaluation of artesunate and artelinate in Plasmodium berghei-infected and uninfected rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artesunate derived from traditional Chinese medicine induces DNA damage and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Embryotoxicity of artesunate in animal species related to drug tissue distribution and toxicokinetic profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

In vivo and in vitro investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) using the Frog Embryo Teratogenesis Assay-Xenopus (FETAX).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Vaccines against malaria - an update

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Randomized comparison of quinine-clindamycin versus artesunate in the treatment of falciparum malaria in pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Ataxia and slurred speech after artesunate treatment for falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

New developments in anthracycline-induced cardiotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Pharmacokinetics of artemisinin-type compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Intramuscular bioavailability and clinical efficacy of artesunate in gabonese children with severe malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Antimalarial drugs in pregnancy: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Antimalarial compounds: from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Toxic brainstem encephalopathy after artemisinin treatment for breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Safety assessment of peroxide antimalarials: clinical and chemical perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Arteether-induced brain injury in Macaca mulatta. I. The precerebellar nuclei: the lateral reticular nuclei, paramedian reticular nuclei, and perihypoglossal nuclei.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Pharmacovigilance in developing countries

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Effect of artesunate on immune cells in ret-transgenic mouse melanoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Comment on: Audiometric changes associated with the treatment of uncomplicated falciparum malaria with co-artemether.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

The economic and social burden of malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Neurotoxic mode of action of artemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Neurotoxicity and toxicokinetics of artelinic acid following repeated oral administration in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Enhanced in vitro neurotoxicity of artemisinin derivatives in the presence of haemin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

The role of glutathione in the neurotoxicity of artemisinin derivatives in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Monitoring antimalarial safety and tolerability in clinical trials: a case study from Uganda

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

A meta-analysis using individual patient data of trials comparing artemether with quinine in the treatment of severe falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Pharmacovigilance of antimalarial treatment in Africa: is it possible?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Antimalarial Drug Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Comparative bioavailability of oral, rectal, and intramuscular artemether in healthy subjects: use of simultaneous measurement by high performance liquid chromatography and bioassay

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Effects of weight, age, and time on artemether-lumefantrine associated ototoxicity and evidence of irreversibility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Audiometric changes associated with the treatment of uncomplicated falciparum malaria with co-artemether

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Response to: artemisinin derivatives: toxic for laboratory animals, safe for humans?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

A trial of artemether or quinine in children with cerebral malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Anti-inflammatory properties and regulatory mechanism of a novel derivative of artemisinin in experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

The Antimalaria Agent Artemisinin Exerts Antiangiogenic Effects in Mouse Embryonic Stem Cell-Derived Embryoid Bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

The effect of artemisinin on granulocyte function assessed by flow cytometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Neurotoxicity of artemisinin analogs in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artemisinin: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Neurological dysfunction following malaria: disease- or drug-related?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Sensitive periods for developmental toxicity of orally administered artesunate in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Recent investigations of artemether, a novel agent for the prevention of schistosomiasis japonica, mansoni and haematobia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Risk assessment and therapeutic indices of artesunate and artelinate in Plasmodium berghei-infected and uninfected rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

Induction of apoptosis by artemisinin relieving the severity of inflammation in caerulein-induced acute pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408441003610571

10.3109/10408441003610571

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20158370%20AND%20SRC:MED&resulttype=core&format=json

release_ljwdz2lvkzd5bpsarun7bdmhdm

18 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ljwdz2lvkzd5bpsarun7bdmhdm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference