(Q37702015)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes (English)

1 reference

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13 March 2020

7

1 reference

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13 March 2020

Andrew J Murphy

12

1 reference

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13 March 2020

author name string

Lynn E Macdonald

1

1 reference

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13 March 2020

Margaret Karow

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Sean Stevens

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Wojtek Auerbach

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

William T Poueymirou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Jason Yasenchak

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

David M Valenzuela

8

1 reference

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13 March 2020

Cosmas C Giallourakis

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Frederick W Alt

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

George D Yancopoulos

11

1 reference

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13 March 2020

language of work or name

English

0 references

publication date

25 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

13 March 2020

published in

1 reference

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13 March 2020

volume

111

1 reference

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13 March 2020

issue

14

1 reference

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13 March 2020

page(s)

5147-5152

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

13 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Analysis of mice lacking DNaseI hypersensitive sites at the 5' end of the IgH locus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Randomized phase III trial results of panitumumab, a fully human anti-epidermal growth factor receptor monoclonal antibody, in metastatic colorectal cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Production and characterization of murine models of classic and intermediate maple syrup urine disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Denosumab in postmenopausal women with low bone mineral density

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyte-associated antigen 4 blockade and interleukin 2: a phase I/II study

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Human antibodies from transgenic animals

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Initial sequencing and comparative analysis of the mouse genome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

A new logic for DNA engineering using recombination in Escherichia coli

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Identification of the crossover site during FLP-mediated recombination in the Saccharomyces cerevisiae plasmid 2 microns circle

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Production of homozygous mutant ES cells with a single targeting construct

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Rapid modification of bacterial artificial chromosomes by ET-recombination.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

From XenoMouse technology to panitumumab, the first fully human antibody product from transgenic mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Identification of a candidate regulatory element within the 5' flanking region of the mouse Igh locus defined by pro-B cell-specific hypersensitivity associated with binding of PU.1, Pax5, and E2A.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Improved properties of FLP recombinase evolved by cycling mutagenesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

The human immunoglobulin kappa locus consists of two copies that are organized in opposite polarity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Manipulating the mouse genome to engineer precise functional syntenic replacements with human sequence.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

A humanized BAC transgenic/knockout mouse model for HbE/beta-thalassemia

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Elucidation of a downstream boundary of the 3' IgH regulatory region

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Differential expression of the inhibitory IgG Fc receptor FcgammaRIIB on germinal center cells: implications for selection of high-affinity B cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3986150

Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1323896111

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1323896111

A Theoretical Model of γ-Globulin Catabolism

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1323896111

DNA cloning by homologous recombination in Escherichia coli

21 January 2018

1 reference

12 December 2020

The immunoglobulin kappa locus: polymorphism and haplotypes of Caucasoid and non-Caucasoid individuals

1 reference

12 December 2020

Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions

1 reference

12 December 2020

Transcriptional behavior of LCR enhancer elements integrated at the same chromosomal locus by recombinase-mediated cassette exchange

1 reference

12 December 2020

Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange

1 reference

12 December 2020

Different role for mouse and human CD3delta/epsilon heterodimer in preT cell receptor (preTCR) function: human CD3delta/epsilon heterodimer restores the defective preTCR function in CD3gamma- and CD3gammadelta-deficient mice

1 reference

12 December 2020

Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1323896111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

24706858

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24706858%20AND%20SRC:MED&resulttype=core&format=json