(Q37704372)

22 August 2017

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title

Stem cell-derived dopamine neurons for brain repair in Parkinson's disease (English)

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22 August 2017

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Rosemary A Fricker-Gates

series ordinal

1

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PubMed ID

20210586

22 August 2017

Monte A Gates

series ordinal

2

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22 August 2017

1 March 2010

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22 August 2017

Regenerative Medicine

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22 August 2017

5

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22 August 2017

2

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22 August 2017

267-278

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Cell therapy in Parkinson's disease

22 August 2017

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Growth and differentiation of aggregating fetal brain cells in a serum-free defined medium

21 January 2018

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Requirements for brain cell attachment, survival and growth in serum-free medium: effects of extracellular matrix, epidermal growth factor and fibroblast growth factor

21 January 2018

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A normal human brain cell aggregate model for neurobiological studies

21 January 2018

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Angiotensin II and interleukin-1 interact to increase generation of dopaminergic neurons from neurospheres of mesencephalic precursors

21 January 2018

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Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines

21 January 2018

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Combination of bFGF, heparin and laminin induce the generation of dopaminergic neurons from rat neural stem cells both in vitro and in vivo.

21 January 2018

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Dopaminergic neuron differentiation of ventral mesencephalic progenitors regulated by developmental signals in vitro

21 January 2018

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Dipyridamole-induced increase in production of rat dopaminergic neurons from mesencephalic precursors

21 January 2018

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Enhancement of dopaminergic differentiation in proliferating midbrain neuroblasts by sonic hedgehog and ascorbic acid.

21 January 2018

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Production of dopaminergic neurons for cell therapy in the treatment of Parkinson's disease

21 January 2018

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The controlled differentiation of human neural stem cells into TH-immunoreactive (ir) neurons in vitro

21 January 2018

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Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3

21 January 2018

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TAT-PAX6 protein transduction in neural progenitor cells: a novel approach for generation of dopaminergic neurones in vitro

21 January 2018

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Control of neurogenesis and tyrosine hydroxylase expression in neural progenitor cells through bHLH proteins and Nurr1.

21 January 2018

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Ngn2 and Nurr1 act in synergy to induce midbrain dopaminergic neurons from expanded neural stem and progenitor cells

21 January 2018

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Donor age affects differentiation of rat ventral mesencephalic stem cells.

21 January 2018

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Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors

21 January 2018

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Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system.

21 January 2018

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Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease.

21 January 2018

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The generation of dopaminergic neurons by human neural stem cells is enhanced by Bcl-XL, both in vitro and in vivo.

21 January 2018

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Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

21 January 2018

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Dopaminergic differentiation of grafted GFP transgenic neuroepithelial stem cells in the brain of a rat model of Parkinson's disease.

21 January 2018

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Distinct efficacy of pre-differentiated versus intact fetal mesencephalon-derived human neural progenitor cells in alleviating rat model of Parkinson's disease.

21 January 2018

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Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.

21 January 2018

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Studies on the differentiation of dopaminergic traits in human neural progenitor cells in vitro and in vivo

21 January 2018

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Functionally deficient neuronal differentiation of mouse embryonic neural stem cells in vitro

21 January 2018

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Embryonic neural progenitor cells: the effects of species, region, and culture conditions on long-term proliferation and neuronal differentiation.

21 January 2018

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Survival of expanded dopaminergic precursors is critical for clinical trials.

21 January 2018

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Induction of dopaminergic neurons from growth factor expanded neural stem/progenitor cell cultures derived from human first trimester forebrain.

21 January 2018

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Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

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Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro

21 January 2018

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Differentiation of embryonic stem cell-derived dopaminergic neurons is enhanced by survival-promoting factors.

21 January 2018

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Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

21 January 2018

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Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity.

21 January 2018

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Early specification of dopaminergic phenotype during ES cell differentiation

21 January 2018

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Behavioral changes in unilaterally 6-hydroxy-dopamine lesioned rats after transplantation of differentiated mouse embryonic stem cells without morphological integration

21 January 2018

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Efficient induction of dopaminergic neurons from embryonic stem cells for application to Parkinson's disease

21 January 2018

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Isolation and transplantation of dopaminergic neurons generated from mouse embryonic stem cells

21 January 2018

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Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro

21 January 2018

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Potential use of embryonic stem cells for the treatment of mouse parkinsonian models: improved behavior by transplantation of in vitro differentiated dopaminergic neurons from embryonic stem cells

21 January 2018

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Persistent dopamine functions of neurons derived from embryonic stem cells in a rodent model of Parkinson disease

21 January 2018

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Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation

21 January 2018

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Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype.

21 January 2018

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Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

21 January 2018

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The homeodomain transcription factor Pitx3 facilitates differentiation of mouse embryonic stem cells into AHD2-expressing dopaminergic neurons.

21 January 2018

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Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease

21 January 2018

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Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells

21 January 2018

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Identification of intrinsic determinants of midbrain dopamine neurons

21 January 2018

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Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons.

21 January 2018

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Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

21 January 2018

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Pharmacological characteristics of rotational behavior in hemiparkinsonian rats transplanted with mouse embryonic stem cell-derived neurons

21 January 2018

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Transplantation of mouse embryonic stem cell-derived neurons into the striatum, subthalamic nucleus and substantia nigra, and behavioral recovery in hemiparkinsonian rats

21 January 2018

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Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity.

21 January 2018

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Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft.

21 January 2018

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Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease

21 January 2018

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Embryonic stem cell lines derived from human blastocysts

21 January 2018

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Induced neuronal differentiation of human embryonic stem cells

21 January 2018

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Generation of dopaminergic neurons in vitro from human embryonic stem cells treated with neurotrophic factors

21 January 2018

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Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells.

21 January 2018

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One year survival and significant reversal of motor deficits in parkinsonian rats transplanted with hESC derived dopaminergic neurons

21 January 2018

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Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats

21 January 2018

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Noggin enhances dopamine neuron production from human embryonic stem cells and improves behavioral outcome after transplantation into Parkinsonian rats

21 January 2018

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Efficient generation of dopamine neurons from human embryonic stem cells

21 January 2018

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Human embryonic stem cell-derived neural precursors as a continuous, stable, and on-demand source for human dopamine neurons.

21 January 2018

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Dopaminergic differentiation of human embryonic stem cells

21 January 2018

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Derivation of midbrain dopamine neurons from human embryonic stem cells

21 January 2018

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Generation of tyrosine hydroxylase positive neurons from human embryonic stem cells after coculture with cellular substrates and exposure to GDNF.

21 January 2018

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Chemically defined sequential culture media for TH+ cell derivation from human embryonic stem cells

21 January 2018

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A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo

21 January 2018

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A novel combination of factors, termed SPIE, which promotes dopaminergic neuron differentiation from human embryonic stem cells

21 January 2018

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Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture

21 January 2018

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Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the bone morphogenic protein antagonist noggin.

21 January 2018

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Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in parkinsonian rats

21 January 2018

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Meningeal cells induce dopaminergic neurons from embryonic stem cells

21 January 2018

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Differentiation of dopaminergic neurons from human embryonic stem cells: modulation of differentiation by FGF-20.

21 January 2018

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Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells.

21 January 2018

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Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

21 January 2018

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Generation of germline-competent induced pluripotent stem cells

21 January 2018

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

21 January 2018

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Generation of human induced pluripotent stem cells from dermal fibroblasts

21 January 2018

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Reprogramming of human somatic cells to pluripotency with defined factors

21 January 2018

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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

21 January 2018

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Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

21 January 2018

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

21 January 2018

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Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

21 January 2018

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Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

21 January 2018

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Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

21 January 2018

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Generation of induced pluripotent stem cells using recombinant proteins

21 January 2018

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The adult rat hippocampus contains primordial neural stem cells

21 January 2018

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Identification of neural stem cells in the adult vertebrate brain

21 January 2018

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In vitro generation of dopaminergic neurons from adult subventricular zone neural progenitor cells

21 January 2018

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Survival and differentiation of adult rat-derived neural progenitor cells transplanted to the striatum of hemiparkinsonian rats.

21 January 2018

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Grafts of adult subependymal zone neuronal progenitor cells rescue hemiparkinsonian behavioral decline

21 January 2018

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Intrastriatal transforming growth factor alpha delivery to a model of Parkinson's disease induces proliferation and migration of endogenous adult neural progenitor cells without differentiation into dopaminergic neurons

21 January 2018

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Evidence for neurogenesis in the adult mammalian substantia nigra

21 January 2018

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Enhanced de novo neurogenesis and dopaminergic neurogenesis in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease-like mice

21 January 2018

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No evidence for new dopaminergic neurons in the adult mammalian substantia nigra

21 January 2018

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Adult bone marrow stromal cells differentiate into neural cells in vitro

21 January 2018

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Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow

21 January 2018

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From marrow to brain: expression of neuronal phenotypes in adult mice.

21 January 2018

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Changing potency by spontaneous fusion.

21 January 2018

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Neuroectodermal differentiation from mouse multipotent adult progenitor cells

21 January 2018

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Brain-derived neurotrophic factor facilitates maturation of mesenchymal stem cell-derived dopamine progenitors to functional neurons.

21 January 2018

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Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation

21 January 2018

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Adult human bone marrow stromal spheres express neuronal traits in vitro and in a rat model of Parkinson's disease

21 January 2018

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Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.

21 January 2018

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Fluorescence-activated cell sorting-based purification of embryonic stem cell-derived neural precursors averts tumor formation after transplantation.

21 January 2018

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Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/RME.10.3

1 reference

22 August 2017

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PubMed ID

20210586