(Q37705120)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20213494%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

HCN-related channelopathies (English)

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19 January 2020

1

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19 January 2020

author name string

Georgia Bottelli

2

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19 January 2020

Raffaella Milanesi

3

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19 January 2020

Jacopo C DiFrancesco

4

1 reference

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19 January 2020

Dario DiFrancesco

5

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19 January 2020

publication date

8 March 2010

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19 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20213494%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

460

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20213494%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

2

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19 January 2020

page(s)

405-415

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https://scigraph.springernature.com/pub.10.1007/s00424-010-0810-8

19 January 2020

exact match

0 references

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12 December 2020

Coupling between voltage sensors and activation gate in voltage-gated K+ channels

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The multiple personalities of h-channels

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Voltage-dependent gating of hyperpolarization-activated, cyclic nucleotide-gated pacemaker channels: molecular coupling between the S4-S5 and C-linkers.

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The human gene coding for HCN2, a pacemaker channel of the heart

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How does adrenaline accelerate the heart?

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Structural basis for modulation and agonist specificity of HCN pacemaker channels

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Structure and function of cardiac pacemaker channels

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Molecular mechanism of cAMP modulation of HCN pacemaker channels.

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The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel.

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Voltage sensor of Kv1.2: structural basis of electromechanical coupling

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Role of pacemaking current in cardiac nodes: insights from a comparative study of sinoatrial node and atrioventricular node

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12 December 2020

Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker

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12 December 2020

Organisation of the mouse sinoatrial node: structure and expression of HCN channels

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12 December 2020

Channelopathies in idiopathic epilepsy

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12 December 2020

Properties of the hyperpolarizing-activated current (if) in cells isolated from the rabbit sino-atrial node

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12 December 2020

The S4-S5 linker couples voltage sensing and activation of pacemaker channels.

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12 December 2020

C terminus-mediated control of voltage and cAMP gating of hyperpolarization-activated cyclic nucleotide-gated channels.

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12 December 2020

Ion channel transcript expression at the rabbit atrioventricular conduction axis.

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12 December 2020

Efficacy of ivabradine, a new selective I(f) inhibitor, compared with atenolol in patients with chronic stable angina

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12 December 2020

Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability

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12 December 2020

Differential distribution and function of hyperpolarization-activated channels in sensory neurons and mechanosensitive fibers.

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12 December 2020

Defective "pacemaker" current (Ih) in a zebrafish mutant with a slow heart rate

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12 December 2020

Mutations in the S4 domain of a pacemaker channel alter its voltage dependence

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12 December 2020

A homology model of the pore region of HCN channels.

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12 December 2020

Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart

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12 December 2020

HCN channels: structure, cellular regulation and physiological function

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12 December 2020

Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide

1 reference

12 December 2020

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

1 reference

12 December 2020

HCN1 ion channel immunoreactivity in spinal cord and medulla oblongata

1 reference

12 December 2020

HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice

1 reference

12 December 2020

The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

1 reference

12 December 2020

Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).

1 reference

12 December 2020

Characterization of the hyperpolarization-activated inward current in isolated human atrial myocytes

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12 December 2020

The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish

1 reference

12 December 2020

Pacemaker current (I(f)) in the human sinoatrial node.

1 reference

12 December 2020

Pacemaker mechanisms in cardiac tissue.

1 reference

12 December 2020

Chloride channelopathies

1 reference

12 December 2020

Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis

1 reference

12 December 2020

Electrophysiological Effects of a Single Intravenous Administration of Ivabradine (S 16257) in Adult Patients with Normal Baseline Electrophysiology

1 reference

12 December 2020

Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues

1 reference

12 December 2020

Action of internal pronase on the f-channel kinetics in the rabbit SA node.

1 reference

12 December 2020

Cardiomyopathic and channelopathic causes of sudden unexplained death in infants and children

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12 December 2020

Voltage gating of ion channels

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12 December 2020

Febrile seizures in the developing brain result in persistent modification of neuronal excitability in limbic circuits

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12 December 2020

Functional stabilization of weakened thalamic pacemaker channel regulation in rat absence epilepsy.

1 reference

12 December 2020

The cardiac hyperpolarizing-activated current, if. Origins and developments

1 reference

12 December 2020

Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel

1 reference

12 December 2020

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues

1 reference

12 December 2020

A family of hyperpolarization-activated mammalian cation channels

1 reference

12 December 2020

Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node

1 reference

12 December 2020

A new interpretation of the pace-maker current in calf Purkinje fibres

1 reference

12 December 2020

Differential distribution of four hyperpolarization-activated cation channels in mouse brain

1 reference

12 December 2020

Mechanisms of human inherited epilepsies

1 reference

12 December 2020

Integrated allosteric model of voltage gating of HCN channels

1 reference

12 December 2020

Properties of the hyperpolarization-activated current (I(f)) in isolated mouse sino-atrial cells

1 reference

12 December 2020

Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart

1 reference

12 December 2020

Developmental febrile seizures modulate hippocampal gene expression of hyperpolarization-activated channels in an isoform- and cell-specific manner

1 reference

12 December 2020

Inherited neuronal ion channelopathies: new windows on complex neurological diseases

1 reference

12 December 2020

Formation of heteromeric hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the hippocampus is regulated by developmental seizures

1 reference

12 December 2020

Two pacemaker channels from human heart with profoundly different activation kinetics

1 reference

12 December 2020

Electrophysiologic changes in heart failure: focus on pacemaker channels

1 reference

12 December 2020

Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS.

1 reference

12 December 2020

The voltage sensor in voltage-dependent ion channels

1 reference

12 December 2020

What keeps us ticking: a funny current, a calcium clock, or both?

1 reference

12 December 2020

Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: a randomized, double-blind, multicentered, placebo-controlled trial

1 reference

12 December 2020

I(f)-dependent modulation of pacemaker rate mediated by cAMP in the presence of ryanodine in rabbit sino-atrial node cells

1 reference

12 December 2020

Site of origin and molecular substrate of atrioventricular junctional rhythm in the rabbit heart

1 reference

12 December 2020

Electrophysiology and pacemaker function of the developing sinoatrial node.

1 reference

12 December 2020

An impaired neocortical Ih is associated with enhanced excitability and absence epilepsy.

1 reference

12 December 2020

Absence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methods

1 reference

12 December 2020

Effects of protein kinase inhibitors on canine Purkinje fibre pacemaker depolarization and the pacemaker current i(f)

1 reference

12 December 2020

Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and Post-S6.

1 reference

12 December 2020

Hyperpolarization-activated cation channels: from genes to function

1 reference

12 December 2020

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

1 reference

12 December 2020

Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node.

1 reference

12 December 2020

Modulation of rate by autonomic agonists in SAN cells involves changes in diastolic depolarization and the pacemaker current

1 reference

12 December 2020

Impaired regulation of thalamic pacemaker channels through an imbalance of subunit expression in absence epilepsy.

1 reference

12 December 2020

Modulation of cyclic nucleotide-regulated HCN channels by PIP(2) and receptors coupled to phospholipase C.

1 reference

12 December 2020

Hyperpolarization-activated cyclic nucleotide-gated channel 1 is a molecular determinant of the cardiac pacemaker current I(f).

1 reference

12 December 2020

HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals

1 reference

12 December 2020

Gating of HCN channels by cyclic nucleotides: residue contacts that underlie ligand binding, selectivity, and efficacy

1 reference

12 December 2020

Comparison of ion-channel subunit expression in canine cardiac Purkinje fibers and ventricular muscle

1 reference

12 December 2020

Queer current and pacemaker: the hyperpolarization-activated cation current in neurons

1 reference

12 December 2020

MiRP1 modulates HCN2 channel expression and gating in cardiac myocytes

1 reference

12 December 2020

Localization of pacemaker channels in lipid rafts regulates channel kinetics

1 reference

12 December 2020

The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium

1 reference

12 December 2020

Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node.

1 reference

12 December 2020

Associated changes in HCN2 and HCN4 transcripts and I(f) pacemaker current in myocytes

1 reference

12 December 2020

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

12 December 2020

Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia

1 reference

12 December 2020

Not so funny anymore: pacing channels are cloned.

1 reference

12 December 2020

HCN pacemaker channels and pain: a drug discovery perspective

1 reference

12 December 2020

A study of the ionic nature of the pace-maker current in calf Purkinje fibres

1 reference

12 December 2020

Evolution and structural diversification of hyperpolarization-activated cyclic nucleotide-gated channel genes

1 reference

12 December 2020

Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3

1 reference

12 December 2020

Hyperpolarization-activated cation currents: from molecules to physiological function

1 reference

12 December 2020

Tamoxifen-inducible gene deletion in the cardiac conduction system

1 reference

12 December 2020

Blocker state dependence and trapping in hyperpolarization-activated cation channels: evidence for an intracellular activation gate

1 reference

12 December 2020

Developmental change in the voltage-dependence of the pacemaker current, if, in rat ventricle cells.

1 reference

12 December 2020

Molecular identification of a hyperpolarization-activated channel in sea urchin sperm

1 reference

12 December 2020

Physiology and pharmacology of the cardiac pacemaker ("funny") current

1 reference

12 December 2020

Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain

1 reference

12 December 2020

Use-dependent inhibition of hHCN4 by ivabradine and relationship with reduction in pacemaker activity

1 reference

12 December 2020

Pacemaker channel dysfunction in a patient with sinus node disease

1 reference

12 December 2020

Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.

1 reference

12 December 2020

Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels

1 reference

12 December 2020

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

1 reference

12 December 2020

Functional heteromerization of HCN1 and HCN2 pacemaker channels

1 reference

12 December 2020

Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia

1 reference

12 December 2020

Molecular pathway for the localized formation of the sinoatrial node

1 reference

12 December 2020

Genesis and regulation of the heart automaticity.

1 reference

12 December 2020

Channelopathies as a genetic cause of epilepsy

1 reference

12 December 2020

Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels

1 reference

12 December 2020