(Q37711271)

22 August 2017

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title

Molecular signaling of the epithelial to mesenchymal transition in generating and maintaining cancer stem cells (English)

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22 August 2017

neoplastic stem cells

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Gaoliang Ouyang

1

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22 August 2017

Zhe Wang

2

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22 August 2017

Xiaoguang Fang

3

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22 August 2017

Jia Liu

4

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22 August 2017

Chaoyong James Yang

5

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22 August 2017

18 March 2010

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Cellular and Molecular Life Sciences

22 August 2017

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22 August 2017

67

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22 August 2017

2605-2618

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22 August 2017

15

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https://scigraph.springernature.com/pub.10.1007/s00018-010-0338-2

22 August 2017

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cites work

Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression

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Crossref

https://api.crossref.org/works/10.1007%2FS00018-010-0338-2

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

21 January 2018

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12 December 2020

Cancer stem cells: mirage or reality?

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12 December 2020

Chemotherapy and cancer stem cells

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12 December 2020

NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells

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12 December 2020

Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression

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12 December 2020

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

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12 December 2020

A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis

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12 December 2020

Targeting cancer stem cells through L1CAM suppresses glioma growth

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12 December 2020

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

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12 December 2020

Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway

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12 December 2020

TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

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12 December 2020

Embryonic stem cell-specific microRNAs promote induced pluripotency

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12 December 2020

Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content

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12 December 2020

Molecular requirements for epithelial-mesenchymal transition during tumor progression

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12 December 2020

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

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12 December 2020

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

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12 December 2020

RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis

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12 December 2020

Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells

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12 December 2020

Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells

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12 December 2020

MicroRNAs: novel regulators in the hallmarks of human cancer

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12 December 2020

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

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12 December 2020

Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.

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12 December 2020

Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition

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12 December 2020

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

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12 December 2020

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12 December 2020

The multifaceted role of periostin in tumorigenesis

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12 December 2020

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

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12 December 2020

Microenvironmental regulation of cancer development

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12 December 2020

Epithelial-mesenchymal transitions in development and disease

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12 December 2020

The basics of epithelial-mesenchymal transition

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12 December 2020

Hypoxia signalling in cancer and approaches to enforce tumour regression

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12 December 2020

Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration

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12 December 2020

Epithelial-mesenchymal transitions: twist in development and metastasis

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12 December 2020

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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12 December 2020

Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins.

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12 December 2020

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

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12 December 2020

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

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12 December 2020

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

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12 December 2020

The Hallmarks of Cancer

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12 December 2020

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

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12 December 2020

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

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12 December 2020

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

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12 December 2020

let-7 regulates self renewal and tumorigenicity of breast cancer cells

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12 December 2020

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression

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12 December 2020

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

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12 December 2020

Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma

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12 December 2020

Endogenous human microRNAs that suppress breast cancer metastasis

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12 December 2020

Micromanagers of malignancy: role of microRNAs in regulating metastasis

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12 December 2020

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

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12 December 2020

Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

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12 December 2020

Identification of selective inhibitors of cancer stem cells by high-throughput screening

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12 December 2020

Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression

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12 December 2020

CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis

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12 December 2020

Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

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12 December 2020

Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer

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12 December 2020

Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation

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12 December 2020

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration

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12 December 2020

A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer

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12 December 2020

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

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12 December 2020

The epithelial-mesenchymal transition generates cells with properties of stem cells

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12 December 2020

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

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12 December 2020

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

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12 December 2020

Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

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12 December 2020

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

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12 December 2020

Osteopontin promotes ovarian cancer progression and cell survival and increases HIF-1alpha expression through the PI3-K/Akt pathway

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12 December 2020

Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity

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12 December 2020

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

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12 December 2020

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

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12 December 2020

Pten, tumorigenesis, and stem cell self-renewal

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12 December 2020

Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition

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12 December 2020

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

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12 December 2020

Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma

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12 December 2020

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

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12 December 2020

Putting tumours in context

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12 December 2020

New signals from the invasive front

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12 December 2020

Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

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12 December 2020

Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition.

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12 December 2020

Hedgehog signaling is dispensable for adult hematopoietic stem cell function

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12 December 2020

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

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12 December 2020

The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling

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12 December 2020

Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition

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12 December 2020

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

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12 December 2020

TGF-beta signaling in tumor suppression and cancer progression

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12 December 2020

Slug, a highly conserved zinc finger transcriptional repressor, protects hematopoietic progenitor cells from radiation-induced apoptosis in vivo.

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12 December 2020

Molecular definition of breast tumor heterogeneity

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12 December 2020

Hypoxia-inducible factors, stem cells, and cancer

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12 December 2020

Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth

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12 December 2020

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

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12 December 2020

Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature

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12 December 2020

The Spemann organizer gene, Goosecoid, promotes tumor metastasis

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12 December 2020

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

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12 December 2020

Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation

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12 December 2020

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

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12 December 2020

Systemic endocrine instigation of indolent tumor growth requires osteopontin

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12 December 2020

Stromal fibroblasts in cancer initiation and progression

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12 December 2020

Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size

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12 December 2020

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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12 December 2020

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

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12 December 2020

YB-1 provokes breast cancer through the induction of chromosomal instability that emerges from mitotic failure and centrosome amplification.

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12 December 2020

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

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12 December 2020

Wnt signalling in stem cells and cancer

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12 December 2020

MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA

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12 December 2020

Complex networks orchestrate epithelial-mesenchymal transitions

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12 December 2020

Generation of breast cancer stem cells through epithelial-mesenchymal transition

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12 December 2020

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

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12 December 2020

Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

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12 December 2020

Prospective identification of tumorigenic breast cancer cells

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12 December 2020

Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment?

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12 December 2020

MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

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12 December 2020

Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients

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12 December 2020

MicroRNAs--the micro steering wheel of tumour metastases

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12 December 2020

Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

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12 December 2020

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

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12 December 2020

Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation

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12 December 2020

Roots and stems: stem cells in cancer.

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12 December 2020

TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma.

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12 December 2020

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

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12 December 2020

MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells

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12 December 2020

Direct regulation of TWIST by HIF-1alpha promotes metastasis

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12 December 2020

Role of hypoxia in the hallmarks of human cancer

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12 December 2020

Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells

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12 December 2020

MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.

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12 December 2020

EMT, the cytoskeleton, and cancer cell invasion

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12 December 2020

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

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12 December 2020

TWIST family of basic helix-loop-helix transcription factors mediate human mesenchymal stem cell growth and commitment.

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12 December 2020

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

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12 December 2020

10.1007/S00018-010-0338-2

Identifiers

DOI

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22 August 2017

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