(Q37718697)

English

Design, synthesis and pharmaco-toxicological assessment of 5-mercapto-1,2,4-triazole derivatives with antibacterial and antiproliferative activity

scientific article published on 14 March 2017

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28350123%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Design, synthesis and pharmaco-toxicological assessment of 5-mercapto-1,2,4-triazole derivatives with antibacterial and antiproliferative activity (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28350123%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

4

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14 March 2020

5

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14 March 2020

Dimitrios Spandidos

11

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14 March 2020

Aristidis Tsatsakis

12

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14 March 2020

Ludovic Kurunczi

13

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14 March 2020

author name string

Marius Mioc

1

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14 March 2020

Codruta Soica

2

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14 March 2020

Vasile Bercean

3

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14 March 2020

Dorina Coricovac

6

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14 March 2020

Roxana Ghiulai

7

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14 March 2020

Delia Muntean

8

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14 March 2020

Florina Andrica

9

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14 March 2020

Cristina Dehelean

10

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14 March 2020

publication date

14 March 2017

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14 March 2020

International Journal of Oncology

1 reference

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14 March 2020

Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)

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23 August 2017

Molecular docking and structure-based drug design strategies

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23 August 2017

The differential susceptibilities of MCF-7 and MDA-MB-231 cells to the cytotoxic effects of curcumin are associated with the PI3K/Akt-SKP2-Cip/Kips pathway.

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23 August 2017

Do we see what we should see? Describing non-covalent interactions in protein structures including precision.

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23 August 2017

NVP-BEZ235, a dual PI3K/mTOR inhibitor synergistically potentiates the antitumor effects of cisplatin in bladder cancer cells

1 reference

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23 August 2017

PIK3CA in Colorectal Cancer

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23 August 2017

3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer.

1 reference

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23 August 2017

Systemic cancer therapy: achievements and challenges that lie ahead

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23 August 2017

Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer

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23 August 2017

Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of EGFR kinase inhibitors in triple-negative breast cancer cells.

1 reference

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23 August 2017

Modulators of sensitivity and resistance to inhibition of PI3K identified in a pharmacogenomic screen of the NCI-60 human tumor cell line collection

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23 August 2017

Structure-based virtual screening for drug discovery: a problem-centric review

1 reference

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23 August 2017

Conformer generation with OMEGA: algorithm and validation using high quality structures from the Protein Databank and Cambridge Structural Database

1 reference

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23 August 2017

The long road to colorectal cancer therapy: searching for the right signals

1 reference

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23 August 2017

mTOR-targeted therapy of cancer with rapamycin derivatives

1 reference

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23 August 2017

The Protein Data Bank

1 reference

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23 August 2017

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells

1 reference

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6 September 2017

Current Challenges in Cancer Treatment

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6 September 2017

The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal kinase signaling in cancer: Alliance or contradiction? (Review).

1 reference

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6 September 2017

FDA-approved small-molecule kinase inhibitors.

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6 September 2017

Synthesis, docking and ADMET studies of novel chalcone triazoles for anti-cancer and anti-diabetic activity

1 reference

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6 September 2017

Targeting the PI3K/Akt pathway in prostate cancer: challenges and opportunities (review).

1 reference

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6 September 2017

The synergistic biologic activity of oleanolic and ursolic acids in complex with hydroxypropyl-γ-cyclodextrin.

1 reference

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6 September 2017

Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro.

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6 September 2017

Signatures of drug sensitivity in nonsmall cell lung cancer

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6 September 2017

Synthesis and antitumor activity of 1,2,4-triazoles having 1,4-benzodioxan fragment as a novel class of potent methionine aminopeptidase type II inhibitors

1 reference

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6 September 2017

Highly Selective and Potent Thiophenes as PI3K Inhibitors with Oral Antitumor Activity

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6 September 2017

Synthesis of some halogen-containing 1,2,4-triazolo-1,3,4-thiadiazines and their antibacterial and anticancer screening studies--part I.

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28 September 2017

Synthesis, antifungal and antibacterial activity of novel 1,2,4-triazole derivatives

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23 June 2018

Predicting the structures of complexes between phosphoinositide 3-kinase (PI3K) and romidepsin-related compounds for the drug design of PI3K/histone deacetylase dual inhibitors using computational docking and the ligand-based drug design approach.

1 reference

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1 September 2018

Synthesis and structure-activity relationships of PI3K/mTOR dual inhibitors from a series of 2-amino-4-methylpyrido[2,3-d]pyrimidine derivatives.

1 reference

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1 September 2018

FRED and HYBRID docking performance on standardized datasets.

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1 September 2018

Synthesis and evaluation of antitumor activities of novel chiral 1,2,4-triazole Schiff bases bearing γ-butenolide moiety

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triazoles: a valuable insight into recent developments and biological activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/28350123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3892/IJO.2017.3912

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28350123%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28350123%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28350123%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

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