(Q37728990)

English

Integrated molecular dissection of the epidermal growth factor receptor (EGFR) [corrected] oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer.

scientific article published on March 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

Europe PubMed Central

Integrated molecular dissection of the epidermal growth factor receptor (EGFR) [corrected] oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

colorectal cancer

1 reference

based on heuristic

inferred from title

corrigendum / erratum

Erratum to: Integrated molecular dissection of the epidermal growth factor receptor (EGFR) oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer

1 reference

10.1007/S11523-010-0142-9

12 July 2019

http://api.crossref.org/works?select=update-to&filter=doi:10.1007/S11523-010-0142-9

Andrea Sartore-Bianchi

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Federica Di Nicolantonio

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Alberto Bardelli

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Salvatore Siena

13

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Katia Bencardino

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Federico Pozzi

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Chiara Funaioli

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Valentina Gambi

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Andrea Cassingena

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Roberta Schiavo

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 March 2010

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Targeted oncology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

19-28

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20383783%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor gene copy number and clinical outcome of metastatic colorectal cancer treated with panitumumab

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR FISH assay predicts for response to cetuximab in chemotherapy refractory colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein overexpression and gene amplification of HER-2 and EGFR in colorectal cancers: an immunohistochemical and fluorescent in situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal Growth Factor Receptor (EGFR) gene copy number (GCN) correlates with clinical activity of irinotecan-cetuximab in K-RAS wild-type colorectal cancer: a fluorescence in situ (FISH) and chromogenic in situ hybridization (CISH) analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of BRAF V600E mutation by pyrosequencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of cetuximab efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RAF/RAS oncogenes and mismatch-repair status

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ras oncogenes in human cancer: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Untangling the ErbB signalling network

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased EGFR gene copy number detected by fluorescent in situ hybridization predicts outcome in non-small-cell lung cancer patients treated with cetuximab and chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential value of PTEN in predicting cetuximab response in colorectal cancer: an exploratory study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prevalence of PIK3CA mutations in gastric and colon cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helical domain and kinase domain mutations in p110alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor expression and gene amplification in colorectal carcinoma: an immunohistochemical and chromogenic in situ hybridization study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRAFMutation in Metastatic Colorectal Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20383783

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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