(Q37731347)

22 August 2017

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title

Oxidative stress and aging: is methylglyoxal the hidden enemy? (English)

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22 August 2017

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Kaushik M Desai

1

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22 August 2017

Tuanjie Chang

2

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22 August 2017

Hui Wang

3

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22 August 2017

Ali Banigesh

4

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22 August 2017

Arti Dhar

5

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22 August 2017

Jianghai Liu

6

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22 August 2017

Ashley Untereiner

7

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22 August 2017

Lingyun Wu

8

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22 August 2017

publication date

1 March 2010

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Canadian Journal of Physiology and Pharmacology

22 August 2017

published in

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22 August 2017

volume

88

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22 August 2017

issue

3

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22 August 2017

page(s)

273-284

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Max Rubner--1854-1932. Energy physiologist

22 August 2017

cites work

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21 January 2018

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Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells

21 January 2018

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Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury

21 January 2018

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Forward and reverse selection for longevity in Drosophila is characterized by alteration of antioxidant gene expression and oxidative damage patterns.

21 January 2018

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Metabolism, not autoxidation, plays a role in alpha-oxoaldehyde- and reducing sugar-induced erythrocyte GSH depletion: relevance for diabetes mellitus

21 January 2018

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Ketosis leads to increased methylglyoxal production on the Atkins diet

21 January 2018

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Glycation (non-enzymic glycosylation) inactivates glutathione reductase

21 January 2018

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Biochemistry of oxygen toxicity

21 January 2018

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Methylglyoxal, oxidative stress, and hypertension

21 January 2018

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21 January 2018

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Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells

21 January 2018

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RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.

21 January 2018

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Aortic stiffness is an independent predictor of progression to hypertension in nonhypertensive subjects

21 January 2018

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Methylglyoxal induces oxidative stress-dependent cell injury and up-regulation of interleukin-1beta and nerve growth factor in cultured hippocampal neuronal cells

21 January 2018

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Semicarbazide-sensitive amine oxidase in vascular smooth muscle cells: differentiation-dependent expression and role in glucose uptake

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Alagebrium chloride protects the heart against oxidative stress in aging rats

21 January 2018

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21 January 2018

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Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon

21 January 2018

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Does chronic glycolysis accelerate aging? Could this explain how dietary restriction works?

21 January 2018

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21 January 2018

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21 January 2018

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Methylglyoxal-induced fibronectin gene expression through Ras-mediated NADPH oxidase activation in renal mesangial cells.

21 January 2018

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The regulation of Escherichia coli methylglyoxal synthase; a new control site in glycolysis?

21 January 2018

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The purification and properties of Escherichia coli methylglyoxal synthase

21 January 2018

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Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice

21 January 2018

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21 January 2018

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Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications

21 January 2018

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The tandem of free radicals and methylglyoxal

21 January 2018

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Has reactive oxygen a role in methylglyoxal toxicity? A study on cultured rat hepatocytes.

21 January 2018

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Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection

21 January 2018

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Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes.

21 January 2018

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Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

21 January 2018

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Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease

21 January 2018

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Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains

21 January 2018

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Aging and resistance to oxidative damage in Caenorhabditis elegans

21 January 2018

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Vitamin C. Biosynthesis, recycling and degradation in mammals

21 January 2018

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Aortic wall damage in mice unable to synthesize ascorbic acid

21 January 2018

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Glyoxalase I activity and immunoreactivity in the aging human lens

21 January 2018

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Mitochondrial DNA repair and aging

21 January 2018

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The evolution of free radicals and oxidative stress

21 January 2018

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An attempt at a rational classification of theories of ageing

21 January 2018

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Molecular mechanisms linking calorie restriction and longevity

21 January 2018

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Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

21 January 2018

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Trends in oxidative aging theories

21 January 2018

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Methylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts

21 January 2018

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Nitric oxide and peroxynitrite in health and disease

21 January 2018

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Modification of enzymatic antioxidants in retinal microvascular cells by glucose or advanced glycation end products

21 January 2018

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Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.

21 January 2018

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The overexpression of major antioxidant enzymes does not extend the lifespan of mice

21 January 2018

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The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach

21 January 2018

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The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal.

21 January 2018

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Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress

21 January 2018

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Oxidative stresses induced by glycoxidized human or bovine serum albumin on human monocytes.

21 January 2018

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Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

21 January 2018

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Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast

21 January 2018

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Extension of murine life span by overexpression of catalase targeted to mitochondria

21 January 2018

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Dicarbonyl-induced accelerated aging in vitro in human skin fibroblasts

21 January 2018

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21 January 2018

On the nature of aging

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Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons

21 January 2018

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Cardiovascular and renal effects of a collagen cross-link breaker (ALT 711) in adult and aged spontaneously hypertensive rats

21 January 2018

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Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension

21 January 2018

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Crosslink breakers: a new approach to cardiovascular therapy

21 January 2018

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Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

21 January 2018

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Transgenic methods for increasing Drosophila life span

21 January 2018

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Superoxide production by the mitochondrial respiratory chain

21 January 2018

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Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

21 January 2018

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Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging

21 January 2018

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Therapeutic potential of AGE inhibitors and breakers of AGE protein cross-links

21 January 2018

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21 January 2018

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Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus.

21 January 2018

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Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells

21 January 2018

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Vascular methylglyoxal metabolism and the development of hypertension

21 January 2018

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Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats.

21 January 2018

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Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure?

21 January 2018

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Invited review: Theories of aging.

21 January 2018

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Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells

21 January 2018

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Involvement of cerebrovascular semicarbazide-sensitive amine oxidase in the pathogenesis of Alzheimer's disease and vascular dementia.

21 January 2018

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Advanced glycation endproduct crosslink breaker (alagebrium) improves endothelial function in patients with isolated systolic hypertension.

21 January 2018

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Free Radicals in Biological Materials

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/Y10-001

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22 August 2017

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