(Q37731720)

22 August 2017

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title

WT1 (Wilms' tumor gene 1): biology and cancer immunotherapy (English)

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22 August 2017

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Haruo Sugiyama

1

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22 August 2017

publication date

15 April 2010

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Japanese Journal of Clinical Oncology

22 August 2017

published in

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22 August 2017

volume

40

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22 August 2017

issue

5

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22 August 2017

page(s)

377-387

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Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Monitoring minimal residual disease in leukemia using real-time quantitative polymerase chain reaction for Wilms tumor gene (WT1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

mRNA expression of leukemia-associated antigens in patients with acute myeloid leukemia for the development of specific immunotherapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Expression of the Wilms' tumor gene WT1 in solid tumors and its involvement in tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Overexpression of the Wilms' tumor gene W T1 in primary astrocytic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Overexpression of the Wilms' tumor gene WT1 in head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Overexpression of the Wilms' tumor gene WT1 in colorectal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Absence of mutations in the Wilms' tumor gene WT1 in primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

WT1-mediated growth suppression of Wilms tumor cells expressing a WT1 splicing variant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

A clinical overview of WT1 gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Cancer immunotherapy targeting Wilms' tumor gene WT1 product

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Constitutive expression of the Wilms' tumor gene WT1 inhibits the differentiation of myeloid progenitor cells but promotes their proliferation in response to granulocyte-colony stimulating factor (G-CSF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

The lck promoter-driven expression of the Wilms tumor gene WT1 blocks intrathymic differentiation of T-lineage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

The Wilms' tumor gene WT1 is a common marker of progenitor cells in fetal liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A*2402-binding residues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Identification of a novel WT1-derived peptide which induces human leucocyte antigen-A24-restricted anti-leukaemia cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Improved human T-cell responses against synthetic HLA-0201 analog peptides derived from the WT1 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Identification of a highly immunogenic HLA-A*01-binding T cell epitope of WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Peptide epitopes from the Wilms' tumor 1 oncoprotein stimulate CD4+ and CD8+ T cells that recognize and kill human malignant mesothelioma tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Identification of a WT1 protein-derived peptide, WT1, as a HLA-A 0206-restricted, WT1-specific CTL epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Prediction of an HLA-DR-binding peptide derived from Wilms' tumour 1 protein and demonstration of in vitro immunogenicity of WT1(124-138)-pulsed dendritic cells generated according to an optimised protocol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Synthetic peptides derived from the Wilms' tumor 1 protein sensitize human T lymphocytes to recognize chronic myelogenous leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Direct recognition and lysis of leukemia cells by WT1-specific CD4+ T lymphocytes in an HLA class II-restricted manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Defining MHC class II T helper epitopes for WT1 tumor antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

WT1 peptide-based immunotherapy for patients with lung cancer: report of two cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

A phase I/II trial of a WT1 (Wilms' tumor gene) peptide vaccine in patients with solid malignancy: safety assessment based on the phase I data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Wilms tumor gene WT1 peptide-based immunotherapy induced a minimal response in a patient with advanced therapy-resistant multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Clinical efficacy of WT1 peptide vaccination in patients with acute myelogenous leukemia and myelodysplastic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Detection of Wilms' tumor antigen--specific CTL in tumor-draining lymph nodes of patients with early breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

WT1 (Wilms tumor 1) peptide immunotherapy for childhood rhabdomyosarcoma: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Th1-biased humoral immune responses against Wilms tumor gene WT1 product in the patients with hematopoietic malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

WT1 IgG antibody for early detection of nonsmall cell lung cancer and as its prognostic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

CD8 T-cell responses to Wilms tumor gene product WT1 and proteinase 3 in patients with acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Ex vivo characterization of multiepitopic tumor-specific CD8 T cells in patients with chronic myeloid leukemia: implications for vaccine development and adoptive cellular immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Monitoring of WT1-specific cytotoxic T lymphocytes after allogeneic hematopoietic stem cell transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

CD8+ T-cell responses to tumor-associated antigens correlate with superior relapse-free survival after allo-SCT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Two distinct HLA-A0201-presented epitopes of the Wilms tumor antigen 1 can function as targets for leukemia-reactive CTL

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

Complete remission in a patient with recurrent acute myeloid leukemia induced by vaccination with WT1 peptide in the absence of hematological or renal toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJJCO%2FHYP194

21 January 2018

Identifiers

DOI

10.1093/JJCO/HYP194

1 reference

22 August 2017

1 reference