(Q37735748)

English

Mitochondrial DNA mutation-elicited oxidative stress, oxidative damage, and altered gene expression in cultured cells of patients with MERRF syndrome

scientific article published on 23 April 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 August 2017

1 reference

Europe PubMed Central

Mitochondrial DNA mutation-elicited oxidative stress, oxidative damage, and altered gene expression in cultured cells of patients with MERRF syndrome (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

mitochondrial DNA

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1 reference

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author name string

Shi-Bei Wu

1

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Yi-Shing Ma

2

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Yu-Ting Wu

3

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Yin-Chiu Chen

4

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Yau-Huei Wei

5

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

publication date

23 April 2010

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Molecular Neurobiology

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Europe PubMed Central

PubMed publication ID

22 August 2017

41

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Europe PubMed Central

PubMed publication ID

22 August 2017

2-3

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Europe PubMed Central

PubMed publication ID

22 August 2017

256-266

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8123-7

21 January 2018

Oxidants in mitochondria: from physiology to diseases

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8123-7

21 January 2018

Activation of PKCdelta and ERK1/2 in the sensitivity to UV-induced apoptosis of human cells harboring 4977 bp deletion of mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8123-7

21 January 2018

Inborn errors of the Krebs cycle: a group of unusual mitochondrial diseases in human

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8123-7

21 January 2018

Response to the increase of oxidative stress and mutation of mitochondrial DNA in aging.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8123-7

21 January 2018

Increasing organismal healthspan by enhancing mitochondrial protein quality control.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of protein carbonyls after two-dimensional electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial mitochondrial encephalomyopathy (MERRF): genetic, pathophysiological, and biochemical characterization of a mitochondrial DNA disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial PHB complex: roles in mitochondrial respiratory complex assembly, ageing and degenerative disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial diseases in man and mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox-dependent matrix metalloproteinase-1 expression is regulated by JNK through Ets and AP-1 promoter motifs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative effect of 4977 bp deletion of mitochondrial DNA on the susceptibility of human cells to UV-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative inactivation of mitochondrial aconitase results in iron and H2O2-mediated neurotoxicity in rat primary mesencephalic cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERp28, a human endoplasmic-reticulum-lumenal protein, is a member of the protein disulfide isomerase family but lacks a CXXC thioredoxin-box motif

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDH E1β deficiency with novel mutations in two patients with Leigh syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic and oxidative stress analysis in human brain samples of Huntington disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidant-antioxidant imbalance in the erythrocytes of sporadic amyotrophic lateral sclerosis patients correlates with the progression of disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional delivery of a cytosolic tRNA into mutant mitochondria of human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations of the mitochondrial proteome caused by the absence of mitochondrial DNA: A proteomic view

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of manganese-superoxide dismutase in fibroblasts of patients with CPEO syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of human intervertebral disc stromelysin and its involvement in matrix degradation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of brain mitochondrial Lon protease by peroxynitrite precedes electron transport chain dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prohibitins and the functional compartmentalization of mitochondrial membranes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide-driven aconitase FE-S center cycling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new mitochondrial transfer RNAPro gene mutation associated with myoclonic epilepsy with ragged-red fibers and other neurological features

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased activities of antioxidant enzymes and decreased ATP concentration in cultured myoblasts with the 3243A-->G mutation in mitochondrial DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in endoplasmic reticulum stress proteins and aldolase A in cells exposed to dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress in human aging and mitochondrial disease-consequences of defective mitochondrial respiration and impaired antioxidant enzyme system

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of reactive oxygen species-elicited apoptosis in the pathophysiology of mitochondrial and neurodegenerative diseases associated with mitochondrial DNA mutations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpressions of myoglobin and antioxidant enzymes in ragged‐red fibers of skeletal muscle from patients with mitochondrial encephalomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of superoxide dismutase induces collagen production in cardiac fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in anti-oxidative defence enzymes in erythrocytes from sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do Mitochondria Produce Oxygen Radicals in vivo?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of reactive oxygen species and antioxidant defenses in complex I deficient patients revealed a specific increase in superoxide dismutase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen peroxide (H2O2) increases the steady-state mRNA levels of collagenase/MMP-1 in human dermal fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA mutations associated with aging and degenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial redox control of matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress biomarkers in mitochondrial myopathies, basally and after cysteine donor supplementation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyruvate dehydrogenase deficiency. Clinical presentation and molecular genetic characterization of five new patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demyelinating disease of central and peripheral nervous systems associated with a A8344G mutation in tRNALys

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased mitochondrial tRNALys steady-state levels and aminoacylation are associated with the pathogenic G8313A mitochondrial DNA mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species-mediated inactivation of pyruvate dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA G8363A mutation in the tRNA Lys gene: clinical, biochemical and pathological study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperammonemia and hepatic encephalopathy stimulate rat cerebral synaptic mitochondrial glutamate dehydrogenase activity specifically in the direction of glutamate oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of matrix metalloproteinase 1 and disruption of mitochondrial network in skin fibroblasts of patients with MERRF syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide anion radical (O2-.), superoxide dismutases, and related matters

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased ATP synthesis is phenotypically expressed during increased energy demand in fibroblasts containing mitochondrial tRNA mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of oxidative stress around the stroke-like lesions of MELAS patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The unique neuroradiology of complex I deficiency due to NDUFA12L defect

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of cDNA encoding the human 150 kDa oxygen-regulated protein, ORP150

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective kinetics of cytochrome c oxidase and alteration of mitochondrial membrane potential in fibroblasts and cytoplasmic hybrid cells with the mutation for myoclonus epilepsy with ragged-red fibres ('MERRF') at position 8344 nt.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic identification of oxidized mitochondrial proteins following experimental traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA mutations and oxidative stress in mitochondrial diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential distribution of the enzymes glutamate dehydrogenase and aspartate aminotransferase in cortical synaptic mitochondria contributes to metabolic compartmentation in cortical synaptic terminals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic study of neuron and astrocyte cultures from senescence-accelerated mouse SAMP8 reveals degenerative changes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial encephalomyopathies: the enigma of genotype versus phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases and their multiple roles in neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative modification of proteins in the frontal cortex of Alzheimer's disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased mitochondrial oxidative damage and oxidative DNA damage contributes to the neurodegenerative process in sporadic amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function and biogenesis of iron-sulphur proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cells bearing mutations causing Leber's hereditary optic neuropathy are sensitized to Fas-Induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteome analysis of human substantia nigra in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 8,344 mutation in mitochondrial DNA: a comparison between the proportion of mutant DNA and clinico-pathologic findings.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of reactive oxygen species in integrin and matrix metalloproteinase expression and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological markers of oxidative stress in mitochondrial myopathies with progressive external ophthalmoplegia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Lon protease is a human stress protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible redox-dependent modulation of mitochondrial aconitase and proteolytic activity during in vivo cardiac ischemia/reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Point mutations in the mitochondrial tRNA(Lys) gene: implications for pathogenesis and mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional consequences of mitochondrial tRNA Trp and tRNA Arg mutations causing combined OXPHOS defects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endoplasmic reticulum quality control and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20411357

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12035-010-8123-7

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

release_26hnnx6hzfbcnpsf2vrg3xbr2m

1 reference

https://api.fatcat.wiki/v0/release/26hnnx6hzfbcnpsf2vrg3xbr2m

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 August 2017

ResearchGate publication ID

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