(Q37737327)

22 August 2017

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title

Cancer-germline antigen vaccines and epigenetic enhancers: future strategies for cancer treatment (English)

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22 August 2017

author name string

Morten Frier Gjerstorff

series ordinal

1

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22 August 2017

Jorge Burns

series ordinal

2

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22 August 2017

Henrik Jorn Ditzel

series ordinal

3

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22 August 2017

language of work or name

English

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publication date

1 July 2010

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Expert Opinion on Biological Therapy

22 August 2017

published in

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22 August 2017

volume

10

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22 August 2017

issue

7

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22 August 2017

page(s)

1061-1075

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Cancer/testis antigens, gametogenesis and cancer

22 August 2017

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21 January 2018

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Immunohistochemical analysis of NY-ESO-1 antigen expression in normal and malignant human tissues

21 January 2018

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Expression of MAGE and GAGE genes in medulloblastoma and modulation of resistance to chemotherapy. Laboratory investigation

21 January 2018

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An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members

21 January 2018

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Molecular mechanisms underlying human synovial sarcoma development

21 January 2018

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NY-ESO-1 and CTp11 expression may correlate with stage of progression in melanoma

21 January 2018

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Detection of MAGE-A transcripts in bone marrow is an independent prognostic factor in operable non-small-cell lung cancer

21 January 2018

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Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer

21 January 2018

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Concise review: cancer/testis antigens, stem cells, and cancer.

21 January 2018

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Cancer/testis antigen expression in human mesenchymal stem cells: down-regulation of SSX impairs cell migration and matrix metalloproteinase 2 expression

21 January 2018

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DNA methylation-associated repression of cancer-germline genes in human embryonic and adult stem cells

21 January 2018

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Epigenetic modulation of cancer-germline antigen gene expression in tumorigenic human mesenchymal stem cells: implications for cancer therapy

21 January 2018

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Cancer testis antigens in human melanoma stem cells: expression, distribution, and methylation status

21 January 2018

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Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells.

21 January 2018

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The melanoma-associated antigen A3 mediates fibronectin-controlled cancer progression and metastasis.

21 January 2018

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MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription

21 January 2018

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MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents

21 January 2018

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MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines

21 January 2018

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Select cancer testes antigens of the MAGE-A, -B, and -C families are expressed in mast cell lines and promote cell viability in vitro and in vivo

21 January 2018

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Melanoma antigen A4 is expressed in non-small cell lung cancers and promotes apoptosis

21 January 2018

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MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity

21 January 2018

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Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family

21 January 2018

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Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein

21 January 2018

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Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilization

21 January 2018

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MAGE Xp-2: a member of the MAGE gene family isolated from an expression library using systemic lupus erythematosus sera

21 January 2018

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A survey of the humoral immune response of cancer patients to a panel of human tumor antigens

21 January 2018

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Proteasome-assisted identification of a SSX-2-derived epitope recognized by tumor-reactive CTL infiltrating metastatic melanoma

21 January 2018

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Monitoring CD8 T cell responses to NY-ESO-1: correlation of humoral and cellular immune responses.

21 January 2018

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A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening

21 January 2018

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NY-ESO-1: review of an immunogenic tumor antigen

21 January 2018

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Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes

21 January 2018

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Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: correlation with antibody responses

21 January 2018

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Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer

21 January 2018

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Expression of MAGE genes in primary and metastatic cutaneous melanoma

21 January 2018

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Prognostic relevance of MAGE-A4 tumor antigen expression in transitional cell carcinoma of the urinary bladder: a tissue microarray study

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Immune and clinical outcomes in patients with stage IV melanoma vaccinated with peptide-pulsed dendritic cells derived from CD34+ progenitors and activated with type I interferon.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Generation of chimeric HBc proteins with epitopes in E.coli: formation of virus-like particles and a potent inducer of antigen-specific cytotoxic immune response and anti-tumor effect in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Heat shock protein 70 / MAGE-1 tumor vaccine can enhance the potency of MAGE-1-specific cellular immune responses in vivo

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

The use of filamentous bacteriophage fd to deliver MAGE-A10 or MAGE-A3 HLA-A2-restricted peptides and to induce strong antitumor CTL responses

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

GSK's antigen-specific cancer immunotherapy programme: pilot results leading to Phase III clinical development

21 January 2018

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Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMATRIX vaccine in patients with advanced malignant melanoma

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Tumor-reactive CD8+ T-cell clones in patients after NY-ESO-1 peptide vaccination

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Safety and immunogenicity study of NY-ESO-1b peptide and montanide ISA-51 vaccination of patients with epithelial ovarian cancer in high-risk first remission.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Immunization with a lentivector that targets tumor antigen expression to dendritic cells induces potent CD8+ and CD4+ T-cell responses

21 January 2018

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Adoptive cell therapy for the treatment of patients with metastatic melanoma

21 January 2018

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Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Rapid alphabeta TCR-mediated responses in gammadelta T cells transduced with cancer-specific TCR genes.

21 January 2018

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Update on anti-CTLA-4 antibodies in clinical trials

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Promoter-dependent mechanism leading to selective hypomethylation within the 5' region of gene MAGE-A1 in tumor cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Epigenetic modulation of solid tumors as a novel approach for cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Characterization and expression of CT45 in Hodgkin's lymphoma

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

De novo induction of a cancer/testis antigen by 5-aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

5-Aza-2'-deoxycytidine (decitabine) treatment of hematopoietic malignancies: a multimechanism therapeutic approach?

21 January 2018

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Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura

21 January 2018

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Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors

21 January 2018

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Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2'-deoxycytidine in cutaneous melanoma: immunotherapeutic implications.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Methylation-regulated expression of HLA class I antigens in melanoma

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Histone deacetylase inhibitors: mechanisms of cell death and promise in combination cancer therapy

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

The synergy of panobinostat plus doxorubicin in acute myeloid leukemia suggests a role for HDAC inhibitors in the control of DNA repair

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

HDAC inhibitor-based therapies and haematological malignancy

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: potential implications for the immunosurveillance of cancer.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Deacetylase inhibition promotes the generation and function of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Intertumor and intratumor NY-ESO-1 expression heterogeneity is associated with promoter-specific and global DNA methylation status in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Heterogeneity of embryonic and adult stem cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

ISCOMATRIX adjuvant induces efficient cross-presentation of tumor antigen by dendritic cells via rapid cytosolic antigen delivery and processing via tripeptidyl peptidase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

NY-ESO-1 protein formulated in ISCOMATRIX adjuvant is a potent anticancer vaccine inducing both humoral and CD8+ t-cell-mediated immunity and protection against NY-ESO-1+ tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

A dendritic cell-based tumour vaccine for lung cancer: full-length XAGE-1b protein-pulsed dendritic cells induce specific cytotoxic T lymphocytes in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Helper T-cell responses and clinical activity of a melanoma vaccine with multiple peptides from MAGE and melanocytic differentiation antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Vaccine-induced CD4+ T cell responses to MAGE-3 protein in lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Immunologic analysis of a phase I/II study of vaccination with MAGE-3 protein combined with the AS02B adjuvant in patients with MAGE-3-positive tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

GM-CSF plus antigenic peptide vaccination in locally advanced melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Phase I/II study of immunotherapy with T-cell peptide epitopes in patients with stage IV melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Autoimmunogenicity of the human sperm protein Sp17 in vasectomized men and identification of linear B cell epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

Prolonged Upregulation of the Expression of HLA Class I Antigens and Co stimulatory Molecules on Melanoma Cells Treated with 5-aza-2??-deoxycytidine (5-AZA-CdR)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2010.485188

10.1517/14712598.2010.485188

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference