(Q37738735)

22 August 2017

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title

Defects in insulin secretion and action in the pathogenesis of type 2 diabetes mellitus (English)

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22 August 2017

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Devjit Tripathy

1

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PubMed ID

20425581

22 August 2017

Alberto O Chavez

series ordinal

2

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22 August 2017

1 June 2010

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22 August 2017

Current diabetes report

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22 August 2017

10

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22 August 2017

3

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22 August 2017

184-191

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https://scigraph.springernature.com/pub.10.1007/s11892-010-0115-5

22 August 2017

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cites work

Familiality of metabolic abnormalities is dependent on age at onset and phenotype of the type 2 diabetic proband

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Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice

21 January 2018

1 reference

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https://api.crossref.org/works/10.1007%2FS11892-010-0115-5

Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia Study

21 January 2018

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12 December 2020

Insulin secretion and insulin sensitivity in diabetic subgroups: studies in the prediabetic and diabetic state

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

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The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study

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The autocrine and paracrine roles of adipokines.

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Glucose absorption and production following oral glucose: comparison of compartmental and arteriovenous-difference methods.

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Insular amyloidosis in spontaneously diabetic nonhuman primates.

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Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects

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12 December 2020

Lipid Infusion Decreases the Expression of Nuclear Encoded Mitochondrial Genes and Increases the Expression of Extracellular Matrix Genes in Human Skeletal Muscle

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12 December 2020

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

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12 December 2020

Pathogenesis of type 2 diabetes mellitus

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Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

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12 December 2020

The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

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12 December 2020

Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus

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12 December 2020

Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.

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12 December 2020

Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects

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12 December 2020

Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects

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12 December 2020

The role for endoplasmic reticulum stress in diabetes mellitus

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12 December 2020

Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus

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12 December 2020

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

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12 December 2020

Inflammation, stress, and diabetes

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Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

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12 December 2020

Proteomic profiling of non-obese type 2 diabetic skeletal muscle

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An update on lipotoxic endoplasmic reticulum stress in pancreatic beta-cells

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The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

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Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies

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Dipeptidyl peptidase-4 inhibition and the treatment of type 2 diabetes: preclinical biology and mechanisms of action

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Biology of incretins: GLP-1 and GIP

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Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

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12 December 2020

Obesity and insulin resistance in humans: a dose-response study.

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12 December 2020

The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7-37) in normal and diabetic subjects

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Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes

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12 December 2020

Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study

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12 December 2020

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

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12 December 2020

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

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Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: results from the Veterans Administration Genetic Epidemiology Study

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A genome-wide association study identifies novel risk loci for type 2 diabetes

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The enteroinsular axis may mediate the diabetogenic effects of TCF7L2 polymorphisms

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12 December 2020

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

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12 December 2020

Parallel manifestation of insulin resistance and beta cell decompensation is compatible with a common defect in Type 2 diabetes

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12 December 2020

Determinants of glucose tolerance in impaired glucose tolerance at baseline in the Actos Now for Prevention of Diabetes (ACT NOW) study

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12 December 2020

The metabolic profile of NIDDM is fully established in glucose-tolerant offspring of two Mexican-American NIDDM parents

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12 December 2020

Glucose clamp technique: a method for quantifying insulin secretion and resistance

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12 December 2020

Defective amplification of the late phase insulin response to glucose by GIP in obese Type II diabetic patients

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12 December 2020

Adipose tissue as an endocrine organ

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12 December 2020

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

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12 December 2020

Pancreatic islet amyloidosis, beta-cell apoptosis, and alpha-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons

1 reference

12 December 2020

Skeletal muscle insulin resistance is the primary defect in type 2 diabetes

1 reference

12 December 2020

Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals

1 reference

12 December 2020

Dose-response effect of elevated plasma free fatty acid on insulin signaling

1 reference

12 December 2020

Effect of short-term free Fatty acids elevation on mitochondrial function in skeletal muscle of healthy individuals

1 reference

12 December 2020

Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group.

1 reference

12 December 2020

Reduced skeletal muscle inhibitor of kappaB beta content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training

1 reference

12 December 2020

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

1 reference

12 December 2020

Beta-cell failure in type 2 diabetes mellitus

1 reference

12 December 2020

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

1 reference

12 December 2020

10.1007/S11892-010-0115-5

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20425581