(Q37746957)

22 August 2017

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title

Partial unfolding and oligomerization of stromal interaction molecules as an initiation mechanism of store operated calcium entry (English)

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22 August 2017

Peter B Stathopulos

1

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22 August 2017

Mitsuhiko Ikura

series ordinal

2

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22 August 2017

publication date

1 April 2010

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Biochemistry and Cell Biology

22 August 2017

published in

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22 August 2017

volume

88

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22 August 2017

issue

2

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22 August 2017

page(s)

175-183

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Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum

22 August 2017

cites work

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The endoplasmic reticulum: a multifunctional signaling organelle

21 January 2018

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Calcium signalling: dynamics, homeostasis and remodelling

21 January 2018

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STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels

21 January 2018

1 reference

Molecular evolution and functional divergence of the Ca(2+) sensor protein in store-operated Ca(2+) entry: stromal interaction molecule

21 January 2018

1 reference

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

21 January 2018

1 reference

STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels

21 January 2018

1 reference

Functional stoichiometry of the unitary calcium-release-activated calcium channel

21 January 2018

1 reference

Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation

21 January 2018

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STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

21 January 2018

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Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.

21 January 2018

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The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions

21 January 2018

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Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

21 January 2018

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STIM1: a novel phosphoprotein located at the cell surface.

21 January 2018

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Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

21 January 2018

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Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

21 January 2018

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A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

21 January 2018

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Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

21 January 2018

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STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

21 January 2018

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STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation

21 January 2018

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Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

21 January 2018

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STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity

21 January 2018

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Orai1 is an essential pore subunit of the CRAC channel

21 January 2018

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A model for receptor-regulated calcium entry

21 January 2018

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New molecular players in capacitative Ca2+ entry

21 January 2018

1 reference

21 January 2018

The many faces of SAM

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STIM1, an essential and conserved component of store-operated Ca2+ channel function

21 January 2018

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STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ Entry

21 January 2018

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Orai1 and STIM reconstitute store-operated calcium channel function

21 January 2018

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Stored Ca2+ depletion-induced oligomerization of stromal interaction molecule 1 (STIM1) via the EF-SAM region: An initiation mechanism for capacitive Ca2+ entry

21 January 2018

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Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry

21 January 2018

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Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics

21 January 2018

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CRACM1 multimers form the ion-selective pore of the CRAC channel.

21 January 2018

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Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins

21 January 2018

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Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation

21 January 2018

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Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane

21 January 2018

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Diversity of conformational states and changes within the EF-hand protein superfamily

21 January 2018

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Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai

21 January 2018

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SOAR and the polybasic STIM1 domains gate and regulate Orai channels

21 January 2018

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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

21 January 2018

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Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2

21 January 2018

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The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels

21 January 2018

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Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1

21 January 2018

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Visualization and Manipulation of Plasma Membrane-Endoplasmic Reticulum Contact Sites Indicates the Presence of Additional Molecular Components within the STIM1-Orai1 Complex

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O09-125

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22 August 2017

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