(Q37761860)

22 August 2017

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title

HspB1 (Hsp 27) expression and neuroprotection in the retina (English)

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22 August 2017

Amanda M O'Reilly

1

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PubMed ID

20514530

22 August 2017

R William Currie

series ordinal

2

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PubMed ID

20514530

22 August 2017

David B Clarke

series ordinal

3

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22 August 2017

2 June 2010

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22 August 2017

Molecular Neurobiology

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22 August 2017

42

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22 August 2017

2

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22 August 2017

124-132

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https://scigraph.springernature.com/pub.10.1007/s12035-010-8143-3

22 August 2017

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cites work

Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8143-3

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-010-8143-3

In vivo chaperone activity of heat shock protein 70 and thermotolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8143-3

Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-010-8143-3

Identification of the phosphorylation sites of the murine small heat shock protein hsp25

21 January 2018

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12 December 2020

On the role of Hsp27 in regulating apoptosis

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12 December 2020

The expression of heat shock protein 27 in retinal ganglion and glial cells in a rat glaucoma model

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12 December 2020

Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo

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12 December 2020

Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

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12 December 2020

Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation

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12 December 2020

Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation.

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12 December 2020

A 25-kD inhibitor of actin polymerization is a low molecular mass heat shock protein

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12 December 2020

Neurodegeneration and cellular stress in the retina and optic nerve in rat cerebral ischemia and hypoperfusion models

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12 December 2020

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

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12 December 2020

Role of p38 mitogen-activated protein kinase in axotomy-induced apoptosis of rat retinal ganglion cells.

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12 December 2020

Hsp27 protects mitochondria of thermotolerant cells against apoptotic stimuli

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12 December 2020

Hsp27 phosphorylation in experimental glaucoma.

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12 December 2020

The number of people with glaucoma worldwide in 2010 and 2020

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12 December 2020

The mechanisms of hsp27 antibody-mediated apoptosis in retinal neuronal cells.

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12 December 2020

Immediate early gene expression in axotomized and regenerating retinal ganglion cells of the adult rat.

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12 December 2020

Dynamic processes that reflect anti-apoptotic strategies set up by HspB1 (Hsp27).

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12 December 2020

The heat-shock proteins

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12 December 2020

Characterization of 45-kDa/54-kDa HSP27 kinase, a stress-sensitive kinase which may activate the phosphorylation-dependent protective function of mammalian 27-kDa heat-shock protein HSP27.

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12 December 2020

Defined sequence segments of the small heat shock proteins HSP25 and alphaB-crystallin inhibit actin polymerization

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12 December 2020

Hsp27 as a negative regulator of cytochrome C release

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12 December 2020

Expression of Hsp27 in retinal ganglion cells of the rat during postnatal development

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12 December 2020

Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology

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12 December 2020

Hsp27 upregulation by HIF-1 signaling offers protection against retinal ischemia in rats.

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12 December 2020

Bax antisense oligonucleotides reduce axotomy-induced retinal ganglion cell death in vivo by reduction of Bax protein expression

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12 December 2020

Retinal preconditioning and the induction of heat-shock protein 27.

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12 December 2020

The toxic effects of glutamate and related compounds in the retina and the brain

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12 December 2020

Expression of small heat shock proteins and intermediate filaments in the human optic nerve head astrocytes exposed to elevated hydrostatic pressure in vitro

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12 December 2020

Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling

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12 December 2020

Apoptosis of Ewing's sarcoma cells is accompanied by accumulation of ubiquitinated proteins

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12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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12 December 2020

Small heat shock proteins are molecular chaperones.

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12 December 2020

Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats.

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12 December 2020

Free radicals in rabbit retina under ocular hyperpressure and functional consequences

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12 December 2020

Molecular chaperones and the cytoskeleton

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12 December 2020

Inhibition of Daxx-mediated apoptosis by heat shock protein 27

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12 December 2020

Subunit exchange of small heat shock proteins. Analysis of oligomer formation of alphaA-crystallin and Hsp27 by fluorescence resonance energy transfer and site-directed truncations

1 reference

12 December 2020

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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12 December 2020

Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27.

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12 December 2020

Hsp27 inhibits cytochrome c-mediated caspase activation by sequestering both pro-caspase-3 and cytochrome c.

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12 December 2020

Hsp25 and -90 immunoreactivity in the normal rat eye.

1 reference

12 December 2020

Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27.

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12 December 2020

HSP27 inhibits cytochrome c-dependent activation of procaspase-9.

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12 December 2020

Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death

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12 December 2020

Role of oxygen free radicals in carcinogenesis and brain ischemia

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12 December 2020

Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand

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12 December 2020

Increased incidence of paraproteinemia and autoantibodies in patients with normal-pressure glaucoma

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12 December 2020

Serum autoantibodies to heat shock proteins in glaucoma patients from Japan and the United States.

1 reference

12 December 2020

Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehydrogenase activity and by maintaining optimal cellular detoxifying machinery

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12 December 2020

Retinal ganglion cell death in glaucoma: mechanisms and neuroprotective strategies

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12 December 2020

Large unphosphorylated aggregates as the active form of hsp27 which controls intracellular reactive oxygen species and glutathione levels and generates a protection against TNFalpha in NIH-3T3-ras cells

1 reference

12 December 2020

Small heat shock protein Hsp27 prevents heat-induced aggregation of F-actin by forming soluble complexes with denatured actin

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12 December 2020

Phosphorylation and supramolecular organization of murine small heat shock protein HSP25 abolish its actin polymerization-inhibiting activity

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12 December 2020

Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27

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12 December 2020

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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12 December 2020

Regulated heat shock protein 27 expression in human retinal pigment epithelium

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12 December 2020

Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3.

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12 December 2020

Injury to retinal ganglion cells induces expression of the small heat shock protein Hsp27 in the rat visual system

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12 December 2020

Heat Shock Protein 27 Controls Apoptosis by Regulating Akt Activation

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12 December 2020

Analysis of chaperone properties of small Hsp's

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12 December 2020

Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II

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12 December 2020

Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector

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12 December 2020

Administration of brain-derived neurotrophic factor suppresses the expression of heat shock protein 27 in rat retinal ganglion cells following axotomy

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12 December 2020

Autoantibodies to small heat shock proteins in glaucoma.

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12 December 2020

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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12 December 2020

Enhanced expression of heat shock protein 27 is correlated with axonal regeneration in mature retinal ganglion cells

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12 December 2020

Immunohistochemical localization of heat shock protein 27 in the retina of pigs.

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12 December 2020

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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12 December 2020

Neuroprotective effects of virally delivered HSPs in experimental stroke

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12 December 2020

Heat shock protein 27 delays Ca2+-induced cell death in a caspase-dependent and -independent manner in rat retinal ganglion cells

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12 December 2020

Redox modulation of NMDA receptor-mediated Ca2+ flux in mammalian central neurons.

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12 December 2020

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

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12 December 2020

Transduced human PEP-1-heat shock protein 27 efficiently protects against brain ischemic insult

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12 December 2020

Protection of retinal ganglion cells from ischemia-reperfusion injury by electrically applied Hsp27.

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12 December 2020

Oxidative stress and TGF-beta2 increase heat shock protein 27 expression in human optic nerve head astrocytes

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12 December 2020

Modulation of actin microfilament dynamics and fluid phase pinocytosis by phosphorylation of heat shock protein 27.

1 reference

12 December 2020

Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels.

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12 December 2020

Hsp27 negatively regulates cell death by interacting with cytochrome c.

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12 December 2020

Death receptors: signaling and modulation

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12 December 2020

Heat shock proteins: regulators of stress response and apoptosis

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12 December 2020

10.1007/S12035-010-8143-3

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20514530